Extension of the linear solvent strength retention model including a parameter that describes the elution strength changes in liquid chromatography

2020 ◽  
Vol 1615 ◽  
pp. 460757 ◽  
Author(s):  
J.J. Baeza-Baeza ◽  
M.C. García-Alvarez-Coque
Keyword(s):  
Liquid Chromatography ◽  
Retention Model ◽  
Solvent Strength ◽  
Strength Retention

scholarly journals Analysis of Non-Ionic Surfactant Triton X-100 Using Hydrophilic Interaction Liquid Chromatography and Mass Spectrometry

Molecules ◽  
2019 ◽  
Vol 24 (7) ◽  
pp. 1223 ◽  
Author(s):  
Evelin Farsang ◽  
Violetta Gaál ◽  
Ottó Horváth ◽  
Erzsébet Bárdos ◽  
Krisztián Horváth
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
High Performance ◽  
Gradient Elution ◽  
Water Soluble ◽  
Ionic Surfactant ◽  
Hydrophilic Interaction ◽  
Retention Model ◽  
Mass Unit ◽  
Triton X

It is well known that surfactants increase the solubility of hydrophobic organic compounds and cause adverse environmental effects. The removal of these compounds from the contaminated soil or ground-water is particularly difficult due to their water soluble feature. In this work, an ultra-high performance hydrophilic interaction liquid chromatographic method was developed for the separation of oligomers of Triton X-100 octylphenol-polyethoxylate non-ionic surfactant. Liquid chromatography-mass spectrometry (LC-MS) was used to identify the Triton X-100 compounds. There was a 44 mass unit difference between two adjacent peaks that is the molar mass of one ethylene oxide group (–CH 2 CH 2 O–). A quadratic retention model was applied for the estimation of retention of the examined non-ionic surfactant and the optimization of gradient elution conditions. The optimized method was suitable for the baseline separation of 28 Triton X-100 oligomers in five minutes.

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