Bio-activation of simeprevir in liver microsomes and characterization of its glutathione conjugates by liquid chromatography coupled to ultrahigh-resolution quadrupole time-of-flight mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2021.462095 ◽

2021 ◽

pp. 462095

Author(s):

Mohamed M.Y. Kaddah ◽

Susan Billig ◽

Ramona Oehme ◽

Claudia Birkemeyer

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Liver Microsomes ◽

Time Of Flight ◽

Ultrahigh Resolution ◽

Glutathione Conjugates ◽

Flight Mass Spectrometry

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1-(Benzo[b]thiophen-4-yl)piperazine Ring Induced Bioactivation of Brexpiprazole in Liver Microsomes: Identification and Characterization of Reactive Conjugates Using Ultra-High-Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry

European Journal of Drug Metabolism and Pharmacokinetics ◽

10.1007/s13318-020-00606-8 ◽

2020 ◽

Vol 45 (3) ◽

pp. 393-403

Author(s):

Disha Thakkar ◽

Abhijeet S. Kate

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Performance ◽

Liver Microsomes ◽

Time Of Flight ◽

Piperazine Ring ◽

Flight Mass Spectrometry ◽

Identification And Characterization

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Characterization of metabolism of (+)-praeruptorin B and (+)-praeruptorin E in human and rat liver microsomes by liquid chromatography coupled with ion trap mass spectrometry and time-of-flight mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.4922 ◽

2011 ◽

Vol 25 (6) ◽

pp. 719-730 ◽

Cited By ~ 18

Author(s):

Yue-Lin Song ◽

Ru Yan ◽

Wang-Hui Jing ◽

Hai-Yu Zhao ◽

Yi-Tao Wang

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Rat Liver ◽

Ion Trap ◽

Liver Microsomes ◽

Time Of Flight ◽

Ion Trap Mass Spectrometry ◽

Rat Liver Microsomes ◽

Flight Mass Spectrometry

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Characterization of in vitro metabolites of trimethoprim and diaveridine in pig liver microsomes by liquid chromatography combined with hybrid ion trap/time-of-flight mass spectrometry

Biomedical Chromatography ◽

10.1002/bmc.1754 ◽

2011 ◽

Vol 26 (9) ◽

pp. 1101-1108 ◽

Cited By ~ 15

Author(s):

Zhao-Ying Liu ◽

Yong Wu ◽

Zhi-Liang Sun ◽

Leren Wan

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Trap ◽

Liver Microsomes ◽

Time Of Flight ◽

Pig Liver ◽

Flight Mass Spectrometry

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Characterization of glutathione conjugates of chloroacetanilide pesticides using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and liquid chromatography/ion trap mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3308 ◽

2007 ◽

Vol 21 (24) ◽

pp. 4017-4022 ◽

Cited By ~ 11

Author(s):

Sandra Pérez ◽

Michael Farkas ◽

Damià Barceló ◽

Diana S. Aga

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Trap ◽

Time Of Flight ◽

Ultra Performance Liquid Chromatography ◽

Ion Trap Mass Spectrometry ◽

Glutathione Conjugates ◽

Flight Mass Spectrometry

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Characterization of in vitro phase I metabolites of methamnetamine in human liver microsomes by liquid chromatography-quadrupole time-of-flight mass spectrometry

International Journal of Legal Medicine ◽

10.1007/s00414-021-02594-z ◽

2021 ◽

Author(s):

Young-ki Hong ◽

Young-Hoon Kim ◽

Jin-Moo Lee ◽

Hye Hyun Yoo ◽

Sun-Ok Choi ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Phase I ◽

Human Liver ◽

Liver Microsomes ◽

Time Of Flight ◽

Human Liver Microsomes ◽

Flight Mass Spectrometry

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Characterization of metabolism feature and potential pharmacological changes of morusin-a promising anti-tumor drug-by ultra-high-performance liquid chromatography coupled time-of-flight mass spectrometry and network pharmacology

Arabian Journal of Chemistry ◽

10.1016/j.arabjc.2020.102964 ◽

2020 ◽

pp. 102964

Author(s):

Feng-xiang Zhang ◽

Yu-lin-lan Yuan ◽

Jing-yun Wang ◽

Zi-ting Li ◽

Shuang-shuang Cui ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Performance ◽

Time Of Flight ◽

Network Pharmacology ◽

Flight Mass Spectrometry

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Systematic screening and characterization of astragalosides in an oral solution of Radix Astragali by liquid chromatography with quadrupole time-of-flight mass spectrometry and Peakview software

Journal of Separation Science ◽

10.1002/jssc.201501278 ◽

2016 ◽

Vol 39 (6) ◽

pp. 1099-1109 ◽

Cited By ~ 8

Author(s):

Chang-Yin Li ◽

Hui-Ting Song ◽

Shi-Jia Liu ◽

Qiong Wang ◽

Guo-Liang Dai ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Time Of Flight ◽

Oral Solution ◽

Radix Astragali ◽

Systematic Screening ◽

Flight Mass Spectrometry

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Biotransformation and Metabolic Profile of Limonin in Rat Liver Microsomes, Bile, and Urine by High-Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry

Journal of Agricultural and Food Chemistry ◽

10.1021/acs.jafc.8b02057 ◽

2018 ◽

Vol 66 (40) ◽

pp. 10388-10393 ◽

Cited By ~ 5

Author(s):

Shijia Liu ◽

Guoliang Dai ◽

Luning Sun ◽

Bingting Sun ◽

Du Chen ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Rat Liver ◽

Metabolic Profile ◽

High Performance ◽

Liver Microsomes ◽

Time Of Flight ◽

Rat Liver Microsomes ◽

Flight Mass Spectrometry

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Comprehensive profiling and characterization of coumarins from roots, stems, leaves, branches, and seeds of Chimonanthus nitens Oliv. using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry combined with modified mass defect filter

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2017.04.016 ◽

2017 ◽

Vol 141 ◽

pp. 140-148 ◽

Cited By ~ 12

Author(s):

Ting Tan ◽

Yun Luo ◽

Chen-Cong Zhong ◽

Xu Xu ◽

Yulin Feng

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Time Of Flight ◽

Ultra Performance Liquid Chromatography ◽

Mass Defect ◽

Flight Mass Spectrometry ◽

Mass Defect Filter

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Characterization of protostane triterpenoids inAlisma orientalisby ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.4548 ◽

2010 ◽

Vol 24 (11) ◽

pp. 1514-1522 ◽

Cited By ~ 40

Author(s):

Xin Liu ◽

Song-Lin Li ◽

Yan Zhou ◽

Jing-Zheng Song ◽

Yun-Feng Zheng ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Time Of Flight ◽

Ultra Performance Liquid Chromatography ◽

Flight Mass Spectrometry

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