267 Transcatheter left atrial appendage closure in high-risk patients with atrial fibrillation who are not eligible for long-term anticoagulation therapy: Initial experience with the amplatzer cardiac plug

2011 ◽  
Vol 27 (5) ◽  
pp. S160
Author(s):  
J. Rodés-Cabau ◽  
J. Champagne ◽  
M. Bernier ◽  
J. Paradis ◽  
J. Sarrazin ◽  
...  
2013 ◽  
Vol 154 (7) ◽  
pp. 262-265
Author(s):  
Zsuzsanna Kis ◽  
Csaba Földesi ◽  
Mátyás Pál ◽  
Zoltán Som ◽  
Andrea Csillik ◽  
...  

The “gold standard” of the prevention of atrial fibrillation related thromboembolic events is anticoagulation therapy with oral vitamin K antagonists. A certain proportion of high-risk patients with atrial fibrillation are not receiving effective antithrombotic therapy because of problems associated with its use. Resolution of subsequent left atrial appendage thrombi is quite a great challenge in patients who are not tolerating “standard” antithrombotic drugs. According to the knowledge of the authors, this is the first report of a patient with non-valvular persistent atrial fibrillation and high stroke risk, who was intolerant to “standard” anticoagulant therapy and had persistent left atrial appendage thrombi following the use of a wide variety of “standard” anticoagulants. Successful resolution of left atrial appendage thrombi with dabigatran and successful percutaneous left atrial appendage closure were performed in this case. Orv. Hetil., 2013, 154, 262–265.


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