107 Pericardiectomy - The Montréal Heart Institute Experience

2012 ◽  
Vol 28 (5) ◽  
pp. S128
Author(s):  
C. Chen ◽  
M. Laflamme ◽  
D. Bouchard ◽  
Y. Hébert ◽  
M. Carrier ◽  
...  
Keyword(s):  
Montreal Heart Institute ◽  
Heart Institute

Abstract 17214: Differential Relationships Between Serum Cholesterol Efflux Capacities Measured From Three Cell Models and Coronary Artery Disease Status in the Montreal Heart Institute Biobank

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
David Rhainds ◽  
Low-Kam Cecile ◽  
Boulé Marie ◽  
Alem Sonia ◽  
Mongrain Ian ◽  
...  
Keyword(s):  
Cholesterol Efflux ◽  
Hdl Cholesterol ◽  
Disease Status ◽  
Cell Types ◽  
P Value ◽  
Montreal Heart Institute ◽  
Cholesterol Efflux Capacity ◽  
Heart Institute ◽  
Control Serum ◽  
The Difference

Recent clinical trials and Mendelian randomization studies suggest that raising HDL-cholesterol (HDL-C) concentration by itself is insufficient to lower cardiovascular (CV) risk, despite the established inverse relationship between HDL-C and cardiovascular risk. CV protection may derive from other characteristics of HDL. Such characteristics include the cholesterol efflux capacity of serum, the process by which HDL particles accept cholesterol from macrophages and other cell types. Recently, higher cholesterol efflux capacity was inversely associated with incident CV events over a >9 year period of follow-up, with a 67% risk reduction in the highest quartile of efflux. In our study, cholesterol efflux capacity was measured for 2000 patients from the Montreal Heart Institute Biobank as the ratio of pooled control serum. When comparing unadjusted cholesterol efflux values between 1000 controls and 1000 cases with previous myocardial infarction (MI), we observed significant decreases of efflux capacity in cases with J774 macrophages in basal and cAMP-stimulated conditions, with human HepG2 hepatocytes and with BHK cells expressing human ABCA1. In regression models of MI status against efflux variables, also adjusted for age, sex, HDL-C, triglycerides and statin use, the reduction in cholesterol efflux capacity in cases vs. controls remained highly significant for J774 cells in basal (p value = 5.8x10-11) and cAMP-stimulated conditions (p = 5.3x10-8), while the difference was lost with HepG2 cells (p=0.16) and was reversed for ABCA1-dependent efflux using BHK-ABCA1 cells (p=5.9x10-4). Thus, the relationship of cholesterol efflux capacity of serum HDL and cardiovascular status is heterogeneous, which suggest that the repertoire of cholesterol transporters expressed in cells and samples characteristics, such as the HDL proteome and lipidome, interact in a unique manner for each cell type. Future work will consist in identifying sources of such differences at the molecular level.

scholarly journals Targeted Temperature Management After Cardiac Arrest: The Montreal Heart Institute Experience

CJC Open ◽  
2019 ◽  
Vol 1 (5) ◽  
pp. 238-244
Author(s):  
Nadia Boulé-Laghzali ◽  
Laura Dominguez Pérez ◽  
Katia Dyrda ◽  
Jean-François Tanguay ◽  
Malorie Chabot-Blanchet ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Targeted Temperature Management ◽  
Temperature Management ◽  
Montreal Heart Institute ◽  
Heart Institute

Seven-year experience with rabbit antithymocyte globulin after cardiac transplantation at the Montreal Heart Institute

1997 ◽  
Vol 29 (7) ◽  
pp. 10S-12S ◽  
Author(s):  
M. Beaufigeau ◽  
D. Dumesnil ◽  
M. Carrier ◽  
M. White ◽  
G.B. Pelletier
Keyword(s):  
Antithymocyte Globulin ◽  
Cardiac Transplantation ◽  
Montreal Heart Institute ◽  
Heart Institute ◽  
Rabbit Antithymocyte Globulin

Restenosis after successful percutaneous transluminal coronary angioplasty: The montreal heart institute experience

1987 ◽  
Vol 60 (3) ◽  
pp. 50-55 ◽  
Author(s):  
Pere Guiteras Val ◽  
Martial G. Bourassa ◽  
Paul Robert David ◽  
Raoul Bonan ◽  
Jacques Crépeau ◽  
...  
Keyword(s):  
Coronary Angioplasty ◽  
Percutaneous Transluminal Coronary Angioplasty ◽  
Montreal Heart Institute ◽  
Heart Institute ◽  
Transluminal Coronary Angioplasty ◽  
Percutaneous Transluminal

Institutional Profile: The Beaulieu-Saucier Université de Montréal Pharmacogenomics Centre at the Montreal Heart Institute

2013 ◽  
Vol 14 (2) ◽  
pp. 131-136
Author(s):  
Marie-Pierre Dubé ◽  
Jean-Claude Tardif
Keyword(s):  
Montreal Heart Institute ◽  
Heart Institute ◽  
Institutional Profile

scholarly journals PROLONGED TEMPORARY PACING WITH BIPOLAR ACTIVE FIXATION PACEMAKER LEADS: INSIGHTS FROM THE MONTRÉAL HEART INSTITUTE EXPERIENCE

2015 ◽  
Vol 31 (10) ◽  
pp. S260
Author(s):  
M.S. Ascoeta ◽  
B. Casteigt ◽  
J. Palazzolo ◽  
S. Venier ◽  
J. Cadrin-Tourigny ◽  
...  
Keyword(s):  
Montreal Heart Institute ◽  
Heart Institute ◽  
Temporary Pacing ◽  
Active Fixation ◽  
Pacemaker Leads

scholarly journals Pericardiectomy for Constrictive Pericarditis: 20 Years of Experience at the Montreal Heart Institute

2015 ◽  
Vol 100 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Nicola Vistarini ◽  
Christina Chen ◽  
Amine Mazine ◽  
Denis Bouchard ◽  
Yves Hebert ◽  
...  
Keyword(s):  
Constrictive Pericarditis ◽  
Years Of Experience ◽  
Montreal Heart Institute ◽  
Heart Institute

Long-term Results of Coronary Artery Bypass Graft Surgery: Experience of the Montreal Heart Institute

1988 ◽  
pp. 542-553
Author(s):  
Lucien Campeau ◽  
Marc Enjalbert ◽  
Claude M. Grondin ◽  
Jacques Lespérance ◽  
Martial G. Bourassa
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Long Term Results ◽  
Artery Bypass Graft ◽  
Montreal Heart Institute ◽  
Heart Institute
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