The role of body symmetry in patients with low back pain, herniated discs and asymptomatic volunteers

Vata Vyadhi is one of the most prevailing health problems in our day today clinical practice, Gridhrasi is one among them. Gridhrasi is Shoola Pradhana Nanatmaja Vatavyadhi, affecting the locomotor system and disable from daily routine activity. Gridhrasi the name itself indicates the way of gait shown by the patient due to extreme pain i.e. like Gridhra or Vulture. Gridhrasi is a condition characterized by Ruk, Toda, Stambha, Spandana in Sphik Pradesha and radiates downwards to Kati, Prusta, Uru, Janu, Jangha and Pada. Gridhrasi can be compared with Sciatica. Pain is the chief cause of person to visit a doctor. Although low back pain is a common condition that affects as many as 80 to 90 percent of people during their lifetime. Gridhrasi can be cured by the help of Vaitarana Basti. Hence in the case study of male patient of age 30 yrs presenting with cardinal clinical sign and symptoms of Gridhrasi are Ruka, Toda and Muhu Spandana in the Sphika, Kati, Uru, Janu, Jangha and Pada in order and Sakthikshepanigraha that is restricted lifting of the leg.

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Role of growth plate (apophyseal ring fracture) in causing modic type changes in pediatric low back pain patients

European Spine Journal ◽

10.1007/s00586-021-06885-2 ◽

2021 ◽

Author(s):

Hiroaki Manabe ◽

Toshinori Sakai ◽

Yasuyuki Omichi ◽

Kosuke Sugiura ◽

Masatoshi Morimoto ◽

...

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Growth Plate ◽

Low Back ◽

Ring Fracture ◽

Modic Type ◽

Pain Patients ◽

Apophyseal Ring Fracture

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Non-Specific Low Back Pain and Lumbar Radiculopathy: Comparison of Morphologic and Compositional MRI as Assessed by gagCEST Imaging at 3T

Diagnostics ◽

10.3390/diagnostics11030402 ◽

2021 ◽

Vol 11 (3) ◽

pp. 402

Author(s):

Miriam Frenken ◽

Sven Nebelung ◽

Christoph Schleich ◽

Anja Müller-Lutz ◽

Karl Ludger Radke ◽

...

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Mixed Model ◽

Linear Mixed Model ◽

Chemical Exchange ◽

Clinical Pathology ◽

Chemical Exchange Saturation Transfer ◽

Low Back ◽

Intervertebral Disks ◽

Asymptomatic Volunteers

Using glycosaminoglycan Chemical Exchange Saturation Transfer (gagCEST) magnetic resonance imaging (MRI), this study comparatively evaluated the GAG contents of lumbar intervertebral disks (IVDs) of patients with non-specific low back pain (nsLBP), radiculopathy, and asymptomatic volunteers to elucidate the association of clinical manifestation and compositional correlate. A total of 18 patients (mean age 57.5 ± 22.5 years) with radiculopathy, 16 age-matched patients with chronic nsLBP and 20 age-matched volunteers underwent standard morphologic and compositional gagCEST MRI on a 3T scanner. In all cohorts, GAG contents of lumbar IVDs were determined using gagCEST MRI. An assessment of morphologic IVD degeneration based on the Pfirrmann classification and T2-weighted sequences served as a reference. A linear mixed model adjusted for multiple confounders was used for statistical evaluation. IVDs of patients with nsLBP showed lower gagCEST values than those of volunteers (nsLBP: 1.3% [99% confidence intervals (CI): 1.0; 1.6] vs. volunteers: 1.9% [99% CI: 1.6; 2.2]). Yet, IVDs of patients with radiculopathy (1.8% [99% CI: 1.4; 2.1]) were not different from patients with nsLBP or volunteers. In patients with radiculopathy, IVDs directly adjacent to IVD extrusions demonstrated lower gagCEST values than distant IVDs (adjacent: 0.9% [99% CI: 0.3; 1.5], distant: 2.1% [99% CI: 1.7; 2.5]). Advanced GAG depletion in nsLBP and directly adjacent to IVD extrusions in radiculopathy indicates close interrelatedness of clinical pathology and compositional degeneration.

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