Roles of high apolipoprotein E blood levels and HDL in development of familial dysbetalipoproteinemia in ε2ε2 subjects

2018 ◽  
Vol 52 ◽  
pp. 67-72 ◽  
Author(s):  
James P. Corsetti ◽  
Charles E. Sparks ◽  
Stephan J.L. Bakker ◽  
Eke G. Gruppen ◽  
Robin P.F. Dullaart
Keyword(s):  
Apolipoprotein E ◽  
Blood Levels ◽  
Familial Dysbetalipoproteinemia

Apolipoprotein E Polymorphisms and the Genetic Heterogeneity of Familial Dysbetalipoproteinemia

1991 ◽  
pp. 71-77
Author(s):  
Louis M. Havekes ◽  
Arn M. J. M. van den Maagdenberg ◽  
Peter de Knijff ◽  
Monique Mulder ◽  
Rune R. Frants
Keyword(s):  
Apolipoprotein E ◽  
Genetic Heterogeneity ◽  
Familial Dysbetalipoproteinemia

scholarly journals Enhanced β2-microglobulin binding of a “navigator” molecule bearing a single-chain variable fragment antibody for artificial switching of metabolic processing pathways

2021 ◽  
Author(s):  
Yusuke Kambe ◽  
Ken Kuwahara ◽  
Mitsuru Sato ◽  
Takahiko Nakaoki ◽  
Tetsuji Yamaoka
Keyword(s):  
Fusion Protein ◽  
Apolipoprotein E ◽  
Blood Levels ◽  
Single Chain Variable Fragment ◽  
Single Chain ◽  
Kidney Dysfunction ◽  
Β2 Microglobulin ◽  
Terminal Domain ◽  
Processing Pathways

Kidney dysfunction increases the blood levels of β2-microglobulin (β2-m), triggering dialysis-related amyloidosis. Previously, we developed a navigator molecule, consisting of a fusion protein of the N-terminal domain of apolipoprotein E...

scholarly journals Variable expression of familial dysbetalipoproteinemia in apolipoprotein E*2 (Lys146-->Gln) Allele carriers.

1994 ◽  
Vol 94 (3) ◽  
pp. 1252-1262 ◽  
Author(s):  
P de Knijff ◽  
A M van den Maagdenberg ◽  
D I Boomsma ◽  
A F Stalenhoef ◽  
A H Smelt ◽  
...  
Keyword(s):  
Apolipoprotein E ◽  
Variable Expression ◽  
Familial Dysbetalipoproteinemia
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