Serum human epididymis protein 4 vs. carbohydrate antigen 125 in ovarian cancer follow-up

2018 ◽  
Vol 60 ◽  
pp. 84-90 ◽  
Author(s):  
Simona Ferraro ◽  
Cristina Robbiano ◽  
Nicoletta Tosca ◽  
Andrea Panzeri ◽  
Anna Maria Paganoni ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Carbohydrate Antigen ◽  
Human Epididymis Protein 4 ◽  
Carbohydrate Antigen 125 ◽  
Human Epididymis

scholarly journals Serum human epididymis protein 4 vs carbohydrate antigen 125 for ovarian cancer diagnosis: a systematic review

2013 ◽  
Vol 66 (4) ◽  
pp. 273-281 ◽  
Author(s):  
Simona Ferraro ◽  
Federica Braga ◽  
Monica Lanzoni ◽  
Patrizia Boracchi ◽  
Elia Mario Biganzoli ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ovarian Cancer ◽  
Cancer Diagnosis ◽  
Carbohydrate Antigen ◽  
Human Epididymis Protein 4 ◽  
Carbohydrate Antigen 125 ◽  
Human Epididymis

Is HE4 Superior over CA-125 in the Follow-up of Patients with Epithelial Ovarian Cancer?

2020 ◽  
Vol 21 (10) ◽  
pp. 1026-1033
Author(s):  
Khalid El Bairi ◽  
Said Afqir ◽  
Mariam Amrani
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Survival Rates ◽  
Carbohydrate Antigen ◽  
Ca 125 ◽  
Poor Survival ◽  
Human Epididymis Protein 4 ◽  
Carbohydrate Antigen 125 ◽  
Improved Accuracy

Notwithstanding important advances in the treatment of epithelial ovarian cancer (EOC), this disease is still a leading cause of global high mortality from gynecological malignancies. Recurrence in EOC is inevitable and it is responsible for poor survival rates. There is a critical need for novel effective biomarkers with improved accuracy compared to the standard carbohydrate antigen-125 (CA-125) for follow-up. The human epididymis protein 4 (HE4) is used for early detection of EOC (ROMA algorithm) as well as for predicting optimal cytoreduction after neoadjuvant chemotherapy and survival outcomes. Notably, the emerging HE4 is a promising prognostic biomarker that has displayed better accuracy in various recent studies for detecting recurrent disease. In this mini-review, we discussed the potential of HE4 as an accurate predictor of EOC recurrence.

Diagnostic value of serum human epididymis protein 4 versus carbohydrate antigen 125 in ovarian cancer

2014 ◽  
Vol 4 (2) ◽  
pp. 66-71
Author(s):  
Moustafa I. Ibrahim ◽  
Ahmed Ibrahim ◽  
Ahmed M. Bahaa ◽  
Marwa M. Yehia ◽  
Mounir M. Fawzy
Keyword(s):  
Ovarian Cancer ◽  
Diagnostic Value ◽  
Carbohydrate Antigen ◽  
Human Epididymis Protein 4 ◽  
Carbohydrate Antigen 125 ◽  
Human Epididymis

scholarly journals Identification of high-risk patients by human epididymis protein 4 levels during follow-up of ovarian cancer

2016 ◽  
Vol 11 (6) ◽  
pp. 3967-3974 ◽  
Author(s):  
KARINA DAHL STEFFENSEN ◽  
MARIANNE WALDSTRØM ◽  
IVAN BRANDSLUND ◽  
BENTE LUND ◽  
SARAH MEJER SØRENSEN ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
High Risk ◽  
Human Epididymis Protein 4 ◽  
High Risk Patients ◽  
Human Epididymis ◽  
Risk Patients
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