Hyporheic hydraulic geometry: Conceptualizing relationships among hyporheic exchange, storage, and water age

Hyporheic exchange is now widely acknowledged as a key driver of ecosystem processes in many streams. Yet stream ecologists have been slow to adopt nuanced hydrologic frameworks developed and applied by engineers and hydrologists to describe the relationship between water storage, water age, and water balance in finite hydrosystems such as hyporheic zones. Here, in the context of hyporheic hydrology, we summarize a well-established mathematical framework useful for describing hyporheic hydrology, while also applying the framework heuristically to visualize the relationships between water age, rates of hyporheic exchange, and water volume within hyporheic zones. Building on this heuristic application, we discuss how improved accuracy in the conceptualization of hyporheic exchange can yield a deeper understanding of the role of the hyporheic zone in stream ecosystems. Although the equations presented here have been well-described for decades, our aim is to make the mathematical basis as accessible as possible and to encourage broader understanding among aquatic ecologists of the implications of tailed age distributions commonly observed in water discharged from and stored within hyporheic zones. Our quantitative description of “hyporheic hydraulic geometry,” associated visualizations, and discussion offer a nuanced and realistic understanding of hyporheic hydrology to aid in considering hyporheic exchange in the context of river and stream ecosystem science and management.

Improved Accuracy and Safety of Pedicle Screw Placement by Using a Probe with an Electrical Conductivity-Measuring Device during Severe Syndromic and Neuromuscular Scoliosis Spine Surgery

An electrical conductivity-measuring device (ECD) has recently been developed to support pedicle screw placement. However, no evidence exists regarding its efficacy for syndromic/neuromuscular scoliosis with extremely difficult screwing. We retrospectively reviewed 2010–2016 medical records of 21 consecutive syndromic/neuromuscular scoliosis patients undergoing free-hand segmental fixation surgery at our institution and compared the pedicle screw insertion accuracy and safety between 10 with a conventional non-ECD probe (2010–2013) and 11 with an ECD probe (2014–2016). We analyzed preoperative pedicle shape and postoperative screw placement in computed tomography. There were no significant differences between ECD and non-ECD groups in demographic, clinical, and treatment characteristics including scoliosis severity and pedicle diameter. The abandonment rate due to liquorrhea or perforation was lower in ECD (12.3%) than in non-ECD (26.7%) (p < 0.01). Acceptable insertion without perforation or <2-mm lateral/cranial position was more frequent in ECD (67.1%) than in non-ECD (56.9%) (p = 0.02). Critical ≥5-mm medial/caudal malposition was not seen in ECD (0.0%) but in non-ECD (2.4%) (p = 0.02). The perforation distance was shorter in ECD (2.2 ± 1.1 mm) than in non-ECD (2.6 ± 1.7 mm) (p = 0.01). Results involve small sample size, selection, performance, and learning curve biases; nevertheless, ECD could be useful for more accurate and safer pedicle screw placement in severe syndromic/neuromuscular scoliosis.

A 2-Gene Host Signature for Improved Accuracy of COVID-19 Diagnosis Agnostic to Viral Variants

The continued emergence of SARS-CoV-2 variants is one of several factors that may cause false negative viral PCR test results. Such tests are also susceptible to false positive results due to trace contamination from high viral titer samples. Host immune response markers provide an orthogonal indication of infection that can mitigate these concerns when combined with direct viral detection. Here, we leverage nasopharyngeal swab RNA-seq data from patients with COVID-19, other viral acute respiratory illnesses and non-viral conditions (n=318) to develop support vector machine classifiers that rely on a parsimonious 2-gene host signature to predict COVID-19. Optimal classifiers achieve an area under the receiver operating characteristic curve (AUC) greater than 0.9 when evaluated on an independent RNA-seq cohort (n=553). We show that a classifier relying on a single interferon-stimulated gene, such as IFI6 or IFI44, measured in RT-qPCR assays (n=144) achieves AUC values as high as 0.88. Addition of a second gene, such as GBP5, significantly improves the specificity compared to other respiratory viruses. The performance of a clinically practical 2-gene RT-qPCR classifier is robust across common SARS-CoV-2 variants, including Omicron, and is unaffected by cross-contamination, demonstrating its utility for improving accuracy of COVID-19 diagnostics.

A Comparison of Various Correction and Blending Techniques for Creating an Improved Satellite-Gauge Rainfall Dataset over Australia

Satellites offer a way of estimating rainfall away from rain gauges which can be utilised to overcome the limitations imposed by gauge density on traditional rain gauge analyses. In this study, Australian station data along with the Japan Aerospace Exploration Agency’s (JAXA) Global Satellite Mapping of Precipitation (GSMaP) and the Bureau of Meteorology’s (BOM) Australian Gridded Climate Dataset (AGCD) rainfall analysis are combined to develop an improved satellite-gauge rainfall analysis over Australia that uses the strengths of the respective data sources. We investigated a variety of correction and blending methods with the aim of identifying the optimal blended dataset. The correction methods investigated were linear corrections to totals and anomalies, in addition to quantile-to-quantile matching. The blending methods tested used weights based on the error variance to MSWEP (Multi-Source Weighted Ensemble Product), distance to the closest gauge, and the error from a triple collocation analysis to ERA5 and Soil Moisture to Rain. A trade-off between away-from- and at-station performances was found, meaning there was a complementary nature between specific correction and blending methods. The most high-performance dataset was one corrected linearly to totals and subsequently blended to AGCD using an inverse error variance technique. This dataset demonstrated improved accuracy over its previous version, largely rectifying erroneous patches of excessive rainfall. Its modular use of individual datasets leads to potential applicability in other regions of the world.

A 2-Gene Host Signature for Improved Accuracy of COVID-19 Diagnosis Agnostic to Viral Variants

The continued emergence of SARS-CoV-2 variants is one of several factors that may cause false negative viral PCR test results. Such tests are also susceptible to false positive results due to trace contamination from high viral titer samples. Host immune response markers provide an orthogonal indication of infection that can mitigate these concerns when combined with direct viral detection. Here, we leverage nasopharyngeal swab RNA-seq data from patients with COVID-19, other viral acute respiratory illnesses and non-viral conditions (n=318) to develop support vector machine classifiers that rely on a parsimonious 2-gene host signature to predict COVID-19. Optimal classifiers achieve an area under the receiver operating characteristic curve (AUC) greater than 0.9 when evaluated on an independent RNA-seq cohort (n=553). We show that a classifier relying on a single interferon-stimulated gene, such as IFI6 or IFI44, measured in RT-qPCR assays (n=144) achieves AUC values as high as 0.88. Addition of a second gene, such as GBP5, significantly improves the specificity compared to other respiratory viruses. The performance of a clinically practical 2-gene RT-qPCR classifier is robust across common SARS-CoV-2 variants, including Omicron, and is unaffected by cross-contamination, demonstrating its utility for improving accuracy of COVID-19 diagnostics.

Automated Aircraft Dent Inspection via a Modified Fourier Transform Profilometry Algorithm

The search for dents is a consistent part of the aircraft inspection workload. The engineer is required to find, measure, and report each dent over the aircraft skin. This process is not only hazardous, but also extremely subject to human factors and environmental conditions. This study discusses the feasibility of automated dent scanning via a single-shot triangular stereo Fourier transform algorithm, designed to be compatible with the use of an unmanned aerial vehicle. The original algorithm is modified introducing two main contributions. First, the automatic estimation of the pass-band filter removes the user interaction in the phase filtering process. Secondly, the employment of a virtual reference plane reduces unwrapping errors, leading to improved accuracy independently of the chosen unwrapping algorithm. Static experiments reached a mean absolute error of ∼0.1 mm at a distance of 60 cm, while dynamic experiments showed ∼0.3 mm at a distance of 120 cm. On average, the mean absolute error decreased by ∼34%, proving the validity of the proposed single-shot 3D reconstruction algorithm and suggesting its applicability for future automated dent inspections.

Analysis of Bluetooth RSSI for Proximity Detection of Ship Passengers

Concern about the health of people who traveled onboard was raised during the COVID-19 outbreak on the Diamond Princess cruise ship. The ship’s narrow space offers an environment conducive to the virus’s spread. Close contact isolation remains one of the most critical current measures to stop the virus’s rapid spread. Contacts can be identified efficiently by detecting intelligent devices nearby. The smartphone’s Bluetooth RSSI signal is essential data for proximity detection. This paper analyzes Bluetooth RSSI signals available to the public and compares RSSI signals in two distinct poses: standing and sitting. These features can improve accuracy and provide an essential basis for creating algorithms for proximity detection. This allows for improved accuracy in identifying close contacts and can help ships sustainably manage persons onboard in the post-epidemic era.

Accurate Prediction of Voltage of Battery Electrode Materials Using Attention Based Graph Neural Networks

Performing first principle calculations to discover electrodes’ properties in the large chemical space is a challenging task. While machine learning (ML) has been applied to effectively accelerate those discoveries, most of the applied methods ignore the materials’ spatial information and only use pre-defined features: based only on chemical compositions. We propose two attention-based graph convolutional neural network techniques to learn the average voltage of electrodes. Our proposed method, which combines both atomic composition and atomic coordinates in 3D-space, improves the accuracy in voltage prediction by 17% when compared to composition based ML models. The first model directly learns the chemical reaction of electrodes and metal-ions to predict their average voltage, whereas the second model combines electrodes’ ML predicted formation energy (Eform) to compute their average voltage. Our models demonstrates improved accuracy in transferability from our subset of learned metal-ions to other metal-ions.

Assessment of risk factors in medical data using improved Binary Artificial Fish Swarm Algorithm with Classification upon Evaluation from F-Test

The objective of this research work is to effectively deploy improved Binary Artificial Fish Swarm optimization Algorithm (BAFSA) with the data classification techniques. The improvement has been made with accordance to the condition of visual scope and the movement of fish to update towards the central position and chasing behavior towards best point of movement has been modified among the given population. The experimental results show that feature selection by BAFSA and classification by Decision trees and Gaussian Naïve bayes algorithm provides an improved accuracy of about 89.6% for Pima Indian diabetic dataset, 91.1% for lenses dataset and 94.4% for heart disease dataset. Statistical analysis has also been made using Fisher’s F-Test for two sample variance and the selected risk factors such as glucose, insulin level, blood pressure for diabetics datasets, spectacle prescription, tear production rate for lenses dataset and trestbps, cholesterol level, thalach, chest pain type for heart disease dataset are found to be significant with R2&lt;0.001 respectively.