scholarly journals Evaluation of the new Beckman Coulter Access hsTnI: 99th percentile upper reference limits according to age and sex in the Korean population

2020 ◽  
Vol 79 ◽  
pp. 48-53 ◽  
Author(s):  
Sollip Kim ◽  
Soo Jin Yoo ◽  
Jongwoo Kim
2009 ◽  
Vol 401 (1-2) ◽  
pp. 162-164 ◽  
Author(s):  
M. Zaninotto ◽  
M.M. Mion ◽  
E. Novello ◽  
E. Delprete ◽  
M. Moretti ◽  
...  

2021 ◽  
Vol 9 ◽  
Author(s):  
Gwo-Tsann Chuang ◽  
I-Jung Tsai ◽  
Yong-Kwei Tsau

Objective: To assess age- and sex-specific serum creatinine levels in a pediatric population using a hospital-based database in Taiwan.Study Design: Data on serum creatinine levels were obtained from the National Taiwan University Hospital-integrated Medical Database (NTUH-iMD). Due to the possibility of having acute kidney injury or chronic kidney disease, individuals with multiple serum creatinine measurements were excluded, and outliers in each age- and sex-specific group were also subsequently removed. The remaining creatinine measurements in each group were analyzed, and 95% reference limits were established.Results: Serum creatinine data of individuals aged between 1 month and 18 years from May 2011 to January 2018 were retrieved. After applying the exclusion criteria, 27,911 individuals with a single corresponding serum creatinine measurement were enrolled. Creatinine level reference limits for each age- and sex-specific group were generated. The upper reference limits (URLs), which are particularly useful in clinical practice, followed the natural trend of increasing serum creatinine with age.Conclusion: We generated serum creatinine reference limits from a single hospital-integrated medical database in Taiwan for different age- and sex-specific groups of children. Our results will aid physicians in clinical practice regarding renal function evaluation, especially for patients without a recent baseline serum creatinine level.


2013 ◽  
Vol 47 (1) ◽  
pp. 76-82 ◽  
Author(s):  
Seung Ha Park ◽  
Nae Yun Heo ◽  
Chang Hoon Kim ◽  
Ki Tae Suk ◽  
Dong Joon Kim ◽  
...  

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Rainer Haeckel ◽  
Werner Wosniok ◽  
Antje Torge ◽  
Ralf Junker ◽  
_ _

AbstractA new model for the indirect estimation of reference limits (RLs) has been proposed recently and was coined TMC approach (truncated minimum chi-square estimation) which can be performed with R statistic. A spline function is applied to the RLs to get a continuous function if age is graphically presented vs. the RLs avoiding artificial “jumps” between different age groups. Most indirect models assume a power normal distribution and fail if this assumption is not fulfilled as e.g. if a relatively high percentage of measured values is below the detection limit and the data are distributed extremely skewed. This problem is handled by the TMC model. High-sensitive cardiac troponin T (hs cTnT) was chosen as an example. The hs cTnT concentration in serum or plasma is well accepted as a valuable marker in the diagnosis of acute myocardial infarction. Currently, the 99th percentile derived from a “healthy” subpopulation is the decision limit recommended by consensus groups. However, this decision limit is questioned by several authors for many reasons. In the present report, the 97.5th and the 99th percentile limits were reinvestigated by the TMC model with different subpopulations stratified according to age and sex and were finally compared to presently recommended decision limits. In summary, the generally recommended 99th percentile as a fixed decision limit should be reconsidered. It is suggested to apply more specific reference limits stratified for age and sex instead of a fixed decision limit.


2013 ◽  
Vol 6 (5) ◽  
pp. 692-699 ◽  
Author(s):  
Susan Cheng ◽  
Martin G. Larson ◽  
Elizabeth L. McCabe ◽  
Ewa Osypiuk ◽  
Birgitta T. Lehman ◽  
...  

2020 ◽  
Vol 42 ◽  
pp. 101646
Author(s):  
U-Young Lee ◽  
Hankyu Kim ◽  
Jin-Kyoung Song ◽  
Dong-Ho Kim ◽  
Kook-Jin Ahn ◽  
...  

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