35. Association of robot-assisted rehabilitation and non-invasive brain stimulation to improve upper limb function in chronic stroke patients

Background. Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood.Objective. To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke patients.Methods. In a within-subject design, seven right-handed chronic stroke patients with upper limb paresis received 21 sessions (3 days/week) of the robot-assisted BAT. The outcomes were changes in score on the upper limb section of the Fugl-Meyer assessment (FM), Motricity Index (MI), and Modified Ashworth Scale (MAS) evaluated at the baseline (T0), posttraining (T1), and 1-month follow-up (T2). Event-related desynchronization/synchronization were calculated in the upper alpha and the beta frequency ranges.Results. Significant improvement in all outcomes was measured over the course of the study. Changes in FM were significant at T2, and in MAS at T1and T2. After training, desynchronization on the ipsilesional sensorimotor areas increased during passive and active movement, as compared with T0.Conclusions. A repetitive robotic-assisted BAT program may improve upper limb motor function and reduce spasticity in the chronically impaired paretic arm. Effects on spasticity were associated with EEG changes over the ipsilesional sensorimotor network.

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Effect of combined somatosensory stimulation and task specific training on upper limb function in chronic stroke patients

http://isrctn.org/> ◽

10.1186/isrctn05542931 ◽

2012 ◽

Author(s):

Jeroen Bergmann

Keyword(s):

Upper Limb ◽

Chronic Stroke ◽

Specific Training ◽

Stroke Patients ◽

Limb Function ◽

Somatosensory Stimulation ◽

Upper Limb Function ◽

And Task

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Recovery of upper-limb function due to enhanced use-dependent plasticity in chronic stroke patients

Brain ◽

10.1093/brain/awq193 ◽

2010 ◽

Vol 133 (11) ◽

pp. 3373-3384 ◽

Cited By ~ 40

Author(s):

S. Koganemaru ◽

T. Mima ◽

M. N. Thabit ◽

T. Ikkaku ◽

K. Shimada ◽

...

Keyword(s):

Upper Limb ◽

Chronic Stroke ◽

Stroke Patients ◽

Limb Function ◽

Dependent Plasticity ◽

Upper Limb Function

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Combining Robotic Training and Non-Invasive Brain Stimulation in Severe Upper Limb-Impaired Chronic Stroke Patients

Frontiers in Neuroscience ◽

10.3389/fnins.2016.00088 ◽

2016 ◽

Vol 10 ◽

Cited By ~ 11

Author(s):

Vincenzo Di Lazzaro ◽

Fioravante Capone ◽

Giovanni Di Pino ◽

Giovanni Pellegrino ◽

Lucia Florio ◽

...

Keyword(s):

Upper Limb ◽

Brain Stimulation ◽

Chronic Stroke ◽

Stroke Patients ◽

Robotic Training ◽

Non Invasive

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Primed Physical Therapy Enhances Recovery of Upper Limb Function in Chronic Stroke Patients

Neurorehabilitation and Neural Repair ◽

10.1177/1545968315595285 ◽

2015 ◽

Vol 30 (4) ◽

pp. 339-348 ◽

Cited By ~ 21

Author(s):

Suzanne J. Ackerley ◽

Winston D. Byblow ◽

P. Alan Barber ◽

Hayley MacDonald ◽

Andrew McIntyre-Robinson ◽

...

Keyword(s):

Physical Therapy ◽

Upper Limb ◽

Chronic Stroke ◽

Stroke Patients ◽

Limb Function ◽

Upper Limb Function

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Do core stability exercises improve upper limb function in chronic stroke patients?

The Egyptian Journal of Neurology Psychiatry and Neurosurgery ◽

10.1186/s41983-019-0087-6 ◽

2019 ◽

Vol 55 (1) ◽

Cited By ~ 2

Author(s):

H. El-Nashar ◽

A. ElWishy ◽

H. Helmy ◽

R. El-Rwainy

Keyword(s):

Upper Limb ◽

Chronic Stroke ◽

Core Stability ◽

Stroke Patients ◽

Limb Function ◽

Upper Limb Function

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Physiotherapy based on problem-solving in upper limb function and neuroplasticity in chronic stroke patients: A case series

Journal of Evaluation in Clinical Practice ◽

10.1111/jep.12921 ◽

2018 ◽

Vol 24 (3) ◽

pp. 552-560 ◽

Cited By ~ 4

Author(s):

Raquel Carvalho ◽

Elsa Azevedo ◽

Paulo Marques ◽

Nuno Dias ◽

João José Cerqueira

Keyword(s):

Problem Solving ◽

Upper Limb ◽

Case Series ◽

Chronic Stroke ◽

Stroke Patients ◽

Limb Function ◽

Upper Limb Function

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The Effect of Applying Robot-Assisted Task-Oriented Training Using Human-Robot Collaborative Interaction Force Control Technology on Upper Limb Function in Stroke Patients: Preliminary Findings

BioMed Research International ◽

10.1155/2021/9916492 ◽

2021 ◽

Vol 2021 ◽

pp. 1-8

Author(s):

Qingming Qu ◽

Yingnan Lin ◽

Zhijie He ◽

Jianghong Fu ◽

Fei Zou ◽

...

Keyword(s):

Upper Limb ◽

Force Control ◽

Interaction Force ◽

Control Technology ◽

Stroke Patients ◽

Robot Assisted ◽

Limb Function ◽

Upper Limb Function ◽

Collaborative Interaction ◽

Clinical Experiments

Stroke is one of the leading causes of death and the primary cause of acquired disability worldwide. Many stroke survivors have difficulty using their upper limbs, which have important functional roles in the performance of daily life activities. Consequently, the independence and quality of life of most stroke patients are reduced. Robot-assisted therapy is an effective intervention for improving the upper limb function of individuals with stroke. Human-robot collaborative interaction force control technology is critical for improving the flexibility and followability of the robot’s motion, thereby improving rehabilitation training outcomes. However, there are few reports on the effect of robot-assisted rehabilitative training on upper limb function. We applied this technology using a robot to assist patients with task-oriented training. Posttreatment changes in Fugl-Meyer and modified Barthel index (MBI) scores were assessed to determine whether this technology could improve the upper limb function of stroke patients. One healthy adult and five stroke patients, respectively, participated in functional and clinical experiments. The MBI and Fugl-Meyer scores of the five patients in the clinical experiments showed significant improvements after the intervention. The experimental results indicate that human-robot collaborative interaction force control technology is valuable for improving robots’ properties and patients’ recovery. This trial was registered in the Chinese clinical trial registry (ChiCTR2000038676).

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