Efficacy and Safety Results From a Phase II, Placebo-Controlled Study of Onartuzumab Plus First-Line Platinum-Doublet Chemotherapy for Advanced Squamous Cell Non–Small-Cell Lung Cancer

Fred R. Hirsch; Ramaswamy Govindan; Zanete Zvirbule; Fadi Braiteh; Achim Rittmeyer; Cristóbal Belda-Iniesta; Dolores Isla; Thomas Cosgriff; Michelle Boyer; Masamichi Ueda; See Phan; David R. Gandara

doi:10.1016/j.cllc.2016.05.011

Efficacy and Safety Results From a Phase II, Placebo-Controlled Study of Onartuzumab Plus First-Line Platinum-Doublet Chemotherapy for Advanced Squamous Cell Non–Small-Cell Lung Cancer

Clinical Lung Cancer ◽

10.1016/j.cllc.2016.05.011 ◽

2017 ◽

Vol 18 (1) ◽

pp. 43-49 ◽

Cited By ~ 16

Author(s):

Fred R. Hirsch ◽

Ramaswamy Govindan ◽

Zanete Zvirbule ◽

Fadi Braiteh ◽

Achim Rittmeyer ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Phase Ii ◽

Small Cell ◽

Controlled Study ◽

Efficacy And Safety ◽

Small Cell Lung ◽

First Line ◽

Doublet Chemotherapy ◽

Platinum Doublet

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Efficacy and Safety Results From a Phase 2, Placebo-Controlled Study of Onartuzumab Plus First-Line Platinum-Doublet Chemotherapy in Advanced Squamous-Cell Non-Small Cell Lung Cancer (sq NSCLC)

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2014.08.215 ◽

2014 ◽

Vol 90 (5) ◽

pp. S37 ◽

Cited By ~ 2

Author(s):

F.R. Hirsch ◽

R. Govindan ◽

Z. Zvirbule ◽

F. Braiteh ◽

A. Rittmeyer ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Small Cell ◽

Controlled Study ◽

Phase 2 ◽

Efficacy And Safety ◽

Small Cell Lung ◽

First Line ◽

Doublet Chemotherapy ◽

Platinum Doublet

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A randomized, phase II study of vandetanib maintenance for advanced or metastatic non-small-cell lung cancer following first-line platinum-doublet chemotherapy

Lung Cancer ◽

10.1016/j.lungcan.2013.08.027 ◽

2013 ◽

Vol 82 (3) ◽

pp. 455-460 ◽

Cited By ~ 25

Author(s):

Jin Seok Ahn ◽

Ki Hyeong Lee ◽

Jong-Mu Sun ◽

Keunchil Park ◽

Eun-Suk Kang ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Randomized Phase Ii ◽

Doublet Chemotherapy ◽

Platinum Doublet

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Efficacy and Safety of Onartuzumab in Combination With First-Line Bevacizumab- or Pemetrexed-Based Chemotherapy Regimens in Advanced Nonsquamous Non-Small Cell Lung Cancer (nsNSCLC): Results From a Phase 2, Placebo-Controlled Study (GO27821)

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2014.08.216 ◽

2014 ◽

Vol 90 (5) ◽

pp. S37-S38 ◽

Cited By ~ 2

Author(s):

H.A. Wakelee ◽

Z. Zvirbule ◽

F. De Braud ◽

C.D. Kingsley ◽

T. Mekhail ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Controlled Study ◽

Phase 2 ◽

Efficacy And Safety ◽

Small Cell Lung ◽

First Line

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Non-small cell lung cancer patients with brain metastases treated with first-line platinum-doublet chemotherapy: Analysis from the European FRAME study

Lung Cancer ◽

10.1016/j.lungcan.2015.11.011 ◽

2015 ◽

Vol 90 (3) ◽

pp. 427-432 ◽

Cited By ~ 29

Author(s):

Denis Moro-Sibilot ◽

Egbert Smit ◽

Javier de Castro Carpeño ◽

Krzysztof Lesniewski-Kmak ◽

Joachim G. Aerts ◽

...

Keyword(s):

Lung Cancer ◽

Brain Metastases ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Lung Cancer Patients ◽

Doublet Chemotherapy ◽

Platinum Doublet

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OA03.02 Nivolumab (NIVO) + ipilimumab (IPI) + 2 Cycles of Platinum-Doublet Chemotherapy (Chemo) vs. 4 Cycles Chemo as First-Line (1L) Treatment) for Stage IV/Recurrent Non-Small Cell Lung Cancer (NSCLC): CheckMate 9LA

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2020.10.022 ◽

2021 ◽

Vol 16 (1) ◽

pp. S2

Author(s):

M. Reck ◽

T.-E. Ciuleanu ◽

M.C. Dols ◽

M. Schenker ◽

B. Zurawski ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Stage Iv ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Doublet Chemotherapy ◽

Platinum Doublet

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Is Gefitinib Combined With Platinum-Doublet Chemotherapy a Counterpart to Osimertinib Monotherapy in Advanced EGFR-Mutated Non–Small-Cell Lung Cancer in the First-Line Setting?

Journal of Clinical Oncology ◽

10.1200/jco.19.02509 ◽

2020 ◽

Vol 38 (8) ◽

pp. 843-844 ◽

Cited By ~ 1

Author(s):

Tomohiro Tanaka ◽

Hiroto Ishiki ◽

Emi Kubo ◽

Sayuri Yokota ◽

Masaki Shimizu ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Line Setting ◽

Egfr Mutated ◽

Doublet Chemotherapy ◽

Platinum Doublet

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A Study of the Efficacy and Safety of RO7198457 in Combination With Atezolizumab Versus Atezolizumab Alone Following Adjuvant Platinum-Doublet Chemotherapy in Participants Who Are ctDNA Positive After Surgical Resection of Stage II-III Non-Small Cell Lung Cancer

Case Medical Research ◽

10.31525/ct1-nct04267237 ◽

2020 ◽

Author(s):

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Surgical Resection ◽

Cell Lung Cancer ◽

Small Cell ◽

Stage Ii ◽

Efficacy And Safety ◽

Small Cell Lung ◽

Doublet Chemotherapy ◽

Platinum Doublet

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378MO EMPOWER-Lung 1: Phase III first-line (1L) cemiplimab monotherapy vs platinum-doublet chemotherapy (chemo) in advanced non-small cell lung cancer (NSCLC) with programmed cell death-ligand 1 (PD-L1) ≥50%

Annals of Oncology ◽

10.1016/j.annonc.2020.10.372 ◽

2020 ◽

Vol 31 ◽

pp. S1388

Author(s):

A. Sezer ◽

S. Kilickap ◽

M. Gümüş ◽

I. Bondarenko ◽

M. Özgüroğlu ◽

...

Keyword(s):

Lung Cancer ◽

Cell Death ◽

Programmed Cell Death ◽

Small Cell Lung Cancer ◽

Small Cell ◽

Phase Iii ◽

Small Cell Lung ◽

First Line ◽

Doublet Chemotherapy ◽

Platinum Doublet

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LBA3 Nivolumab (NIVO) + platinum-doublet chemotherapy (chemo) vs chemo as first-line (1L) treatment (tx) for advanced non-small cell lung cancer (aNSCLC): CheckMate 227 - part 2 final analysis

Annals of Oncology ◽

10.1093/annonc/mdz453.004 ◽

2019 ◽

Vol 30 ◽

pp. xi67-xi68 ◽

Cited By ~ 8

Author(s):

L. Paz-Ares ◽

T.E. Ciuleanu ◽

X. Yu ◽

P. Salman ◽

A. Pluzanski ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Final Analysis ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Doublet Chemotherapy ◽

Platinum Doublet

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OA03.03 Nivolumab (NIVO) + ipilimumab (IPI) Versus Platinum-Doublet Chemotherapy (Chemo) as First-Line (1L) Treatment for Advanced Non-Small Cell Lung Cancer (aNSCLC): 3-year Update from CheckMate 227 Part 1

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2020.10.023 ◽

2021 ◽

Vol 16 (1) ◽

pp. S2-S3

Author(s):

S.S. Ramalingam ◽

T.E. Ciuleanu ◽

A. Pluzanski ◽

J.-S. Lee ◽

M. Schenker ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

First Line ◽

Doublet Chemotherapy ◽

Platinum Doublet

Download Full-text