Local synchronization indices for rotors detection in atrial fibrillation: A simulation study

2021 ◽  
Vol 94 ◽  
pp. 105548
Author(s):  
Andrés Orozco-Duque ◽  
Juan P. Ugarte ◽  
Catalina Tobón
Keyword(s):  
Atrial Fibrillation ◽  
Simulation Study ◽  
Local Synchronization

scholarly journals P797Effect of sodium channel blockade on the 3-dimensional substrate of atrial fibrillation: a simulation study

EP Europace ◽  
2018 ◽  
Vol 20 (suppl_1) ◽  
pp. i142-i142
Author(s):  
A Gharaviri ◽  
M Potse ◽  
R Krause ◽  
A Auricchio ◽  
U Schotten
Keyword(s):  
Atrial Fibrillation ◽  
Sodium Channel ◽  
Simulation Study ◽  
Channel Blockade ◽  
3 Dimensional

scholarly journals Characterization of Electrograms from Multipolar Diagnostic Catheters during Atrial Fibrillation

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Prasanth Ganesan ◽  
Elizabeth M. Cherry ◽  
Arkady M. Pertsov ◽  
Behnaz Ghoraani
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Simulation Study ◽  
Cycle Length ◽  
Human Subject ◽  
Conduction Delay ◽  
Ablation Procedure ◽  
Endocardial Surface ◽  
Diagnostic Catheter

Atrial fibrillation (AF) is the most common arrhythmia in USA with more than 2.3 million people affected annually. Catheter ablation procedure is a method for treatment of AF, which involves 3D electroanatomic mapping of the patient's left atrium (LA) by maneuvering a conventional multipolar diagnostic catheter (MPDC) along the LA endocardial surface after which pulmonary vein (PV) isolation is performed, thus eliminating the AF triggers originating from the PVs. However, it remains unclear how to effectively utilize the information provided by the MPDC to locate the AF-sustaining sites, known as sustained rotor-like activities (RotAs). In this study, we use computer modeling to investigate the variations in the characteristics of the MPDC electrograms, namely, total conduction delay (TCD) and average cycle length (CL), as the MPDC moves towards a RotA source. Subsequently, a study with a human subject was performed in order to verify the predictions of the simulation study. The conclusions from this study may be used to iteratively direct an MPDC towards RotA sources thus allowing the RotAs to be localized for customized and improved AF ablation.

scholarly journals Effects of Electrical and Structural Remodeling on Atrial Fibrillation Maintenance: A Simulation Study

2012 ◽  
Vol 8 (2) ◽  
pp. e1002390 ◽  
Author(s):  
Trine Krogh-Madsen ◽  
Geoffrey W. Abbott ◽  
David J. Christini
Keyword(s):  
Atrial Fibrillation ◽  
Simulation Study ◽  
Structural Remodeling
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