Polydopamine/carboxylic graphene oxide-composited polypyrrole films for promoting adhesion and alignment of Schwann cells

2020 ◽  
Vol 191 ◽  
pp. 110972 ◽  
Author(s):  
Ya Li ◽  
Zhongbing Huang ◽  
Ximing Pu ◽  
Xianchun Chen ◽  
Guangfu Yin ◽  
...  
Author(s):  
Zhiqiang Huang ◽  
Manman Sun ◽  
Yanyi Li ◽  
Zhenzhao Guo ◽  
Hong Li

A conductive fibrous scaffold with typical aligned topography is beneficial for the adhesion, proliferation, NGF secretion and migration of Schwann cells under electrical stimulation.


2018 ◽  
Vol 106 (7) ◽  
pp. 1951-1964 ◽  
Author(s):  
Yinxin Zhao ◽  
Yingjie Wang ◽  
Changmei Niu ◽  
Luzhong Zhang ◽  
Guicai Li ◽  
...  

2015 ◽  
Vol 5 (6) ◽  
pp. 472-478
Author(s):  
Luzhong Zhang ◽  
Fan Liu ◽  
Yahong Zhao ◽  
Guicai Li ◽  
Youlang Zhou ◽  
...  
Keyword(s):  

2016 ◽  
Vol 143 ◽  
pp. 547-556 ◽  
Author(s):  
Guicai Li ◽  
Yinxin Zhao ◽  
Luzhong Zhang ◽  
Ming Gao ◽  
Yan Kong ◽  
...  

Author(s):  
Å. Thureson-Klein

Giant mitochondria of various shapes and with different internal structures and matrix density have been observed in a great number of tissues including nerves. In most instances, the presence of giant mitochondria has been associated with a known disease or with abnormal physiological conditions such as anoxia or exposure to cytotoxic compounds. In these cases degenerative changes occurred in other cell organelles and, therefore the giant mitochondria also were believed to be induced structural abnormalities.Schwann cells ensheating unmyelinated axons of bovine splenic nerve regularly contain giant mitochondria in addition to the conventional smaller type (Fig. 1). These nerves come from healthy inspected animals presumed not to have been exposed to noxious agents. As there are no drastic changes in the small mitochondria and because other cell components also appear reasonably well preserved, it is believed that the giant mitochondria are normally present jin vivo and have not formed as a post-mortem artifact.


Author(s):  
R.L. Martuza ◽  
T. Liszczak ◽  
A. Okun ◽  
T-Y Wang

Neurofibromatosis (NF) is an autosomal dominant genetic disorder with a prevalence of 1/3,000 births. The NF mutation causes multiple abnormalities of various cells of neural crest origin. Schwann cell tumors (neurofibromas, acoustic neuromas) are the most common feature of neurofibromatosis although meningiomas, gliomas, and other neoplasms may be seen. The schwann cell tumors commonly develop from the schwann cells associated with sensory or sympathetic nerves or their ganglia. Schwann cell tumors on ventral spinal roots or motor cranial nerves are much less common. Since the sensory neuron membrane is known to contain a mitogenic factor for schwann cells, we have postulated that neurofibromatosis may be due to an abnormal interaction between the nerve and the schwann cell and that this interaction may be hormonally modulated. To test this possibility a system has been developed in which an enriched schwannoma cell culture can be obtained and co-cultured with pure neurons.


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