Gallic acid-loaded chitosan nanoparticles: A preliminary study

2011 ◽  
Vol 22 ◽  
pp. S127
Author(s):  
Cigdem Yucel ◽  
Gokce Seker Karatoprak ◽  
Yesim Aktas ◽  
Muberra Kosar
Keyword(s):  
Gallic Acid ◽  
Chitosan Nanoparticles ◽  
Preliminary Study

Gallic acid loaded poloxamer gel as new adjuvant strategy for melanoma: A preliminary study

2020 ◽  
Vol 185 ◽  
pp. 110613 ◽  
Author(s):  
Maddalena Sguizzato ◽  
Giuseppe Valacchi ◽  
Alessandra Pecorelli ◽  
Paola Boldrini ◽  
Fanny Simelière ◽  
...  
Keyword(s):  
Gallic Acid ◽  
Preliminary Study ◽  
Poloxamer Gel

Improved Neuroprotective Effects of Gallic Acid-Loaded Chitosan Nanoparticles Against Ischemic Stroke

2020 ◽  
Vol 23 (4) ◽  
pp. 284-292 ◽  
Author(s):  
Yongmei Zhao ◽  
Duolu Li ◽  
Zhenfeng Zhu ◽  
Ya Sun
Keyword(s):  
Ischemic Stroke ◽  
Gallic Acid ◽  
Chitosan Nanoparticles ◽  
Neuroprotective Effects

scholarly journals Formulation and Characterization of gallic acid and quercetin chitosan nanoparticles for sustained release in treating Colorectal Cancer

2021 ◽  
Author(s):  
Poournima Patil ◽  
Suresh Killedar
Keyword(s):  
Colorectal Cancer ◽  
Gallic Acid ◽  
Chitosan Nanoparticles ◽  
Entrapment Efficiency ◽  
Aberrant Crypt Foci ◽  
Spectroscopic Techniques ◽  
X Ray Diffraction ◽  
Scanning Calorimetry

Abstract The current work was addressed to characterize gallic acid from amla fruit and quercetin from peels of pomegranate fruit and formulated into Chitosan (CS) nanoparticles and to evaluate their cytotoxicity towards human colorectal cancer (HCT 116) cell lines for the treatment of DMH induced colorectal cancer in Wistar rats. Identification of the biomolecules was performed by using different chromatographic and spectroscopic techniques, as 1H-NMR, GC-MS, LC-MS and HPTLC. Characterization of CS nanoparticles carried out by using X- ray diffraction (XRD) Differential scanning calorimetry (DSC), Scanning Electron Microscope (SEM), entrapment efficiency and In vitro drug release confirmed successful encapsulation of biomolecules into CS nanoparticles. A significant change in aberrant crypt foci (ACF) in CS nanoparticles compared to polyherbal extract were observed, with decrease in the colonic glutathione, catalase and superoxide dismutase levels and values differed significantly (P < 0.005).

scholarly journals A preliminary study of the incorparation of NPK fertilizer into chitosan nanoparticles

2010 ◽  
Vol 4 (8) ◽  
pp. 509-515 ◽  
Author(s):  
E. Corradini ◽  
M. R. de Moura ◽  
L. H. C. Mattoso
Keyword(s):  
Chitosan Nanoparticles ◽  
Npk Fertilizer ◽  
Preliminary Study

scholarly journals Chitosan Nanoparticles Stabilized with Gallic Acid, Never-Dried Bacterial Nanocellulose, and Alginate Have Biostimulant Potential for Plants

Proceedings ◽  
2019 ◽  
Vol 29 (1) ◽  
pp. 59
Author(s):  
Stefan-Ovidiu Dima ◽  
Anca-Andreea Turcanu ◽  
Sanda-Maria Doncea ◽  
Victor Faraon ◽  
Elena Radu ◽  
...  
Keyword(s):  
Plant Growth ◽  
Gallic Acid ◽  
Plant Development ◽  
Chitosan Nanoparticles ◽  
Field Monitoring ◽  
Bacterial Nanocellulose ◽  
Growth Trends ◽  
Advanced Analysis

Current plant growth trends coupled with advanced analysis and in-field monitoring are oriented towards new agricultural inputs that protect and stimulate plant development. [...]

Colon Available Bioactive Compounds Exhibits Anticancer Effect on In-Vitro Model of Colorectal Cancer

2021 ◽  
Author(s):  
Poounima Patil ◽  
Suresh Killedar
Keyword(s):  
Colorectal Cancer ◽  
Gallic Acid ◽  
Hct116 Cell ◽  
Chitosan Nanoparticles ◽  
Entrapment Efficiency ◽  
Spectroscopic Techniques ◽  
X Ray Diffraction ◽  
Hct 116 ◽  
Vitro Model

The current work was addressed to characterize gallic acid from amla fruit and quercetin from peels of pomegranate fruit and formulated into Chitosan (CS) nanoparticles and to evaluate their cytotoxicity towards human colorectal cancer (HCT 116) cell lines. Identification of the biomolecules was performed by chromatographic and spectroscopic techniques and characterization of gallic acid and quercetin loaded chitosan nanoparticles carried out by using FT-IR, X- ray diffraction, entrapment efficiency and loading content confirmed successful encapsulation of biomolecules into nanoparticles. In vitro drug release studies done by using simulated fluids at various pH (1.2, 4.5, 7.5, and 7.0) to mimic the GIT tract and achieved drug releases 77.56% for gallic acid 79.06% for quercetin at 24 hr. in a sustained manner. The human HCT116 cell line by MTT assay results inferred that the synthesized CS nanoparticles demonstrated shows more effective antiproliferative potential with IC50 value of 36.17 ug/ml than polyherbal extract 60.32ug/ml.

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