Genetic polymorphisms and HPV infection in oral squamous cell carcinomas

2015 ◽  
Vol 14 ◽  
pp. 1-6 ◽  
Author(s):  
Yan Sun ◽  
Yang Zhang ◽  
Limei Liu ◽  
Xicheng Song ◽  
Guojun Li
2006 ◽  
Vol 20 (1) ◽  
pp. 21-24 ◽  
Author(s):  
Elena Riet Correa Rivero ◽  
Fabio Daumas Nunes

Human Papilomaviruses (HPV) are a group of viruses associated with benign and malignant lesions of cutaneous and mucosal epithelia. Some "high risk" HPV types, especially HPV 16 and 18, are strongly correlated with cervical and anogenital cancers and are also related to the genesis of oral squamous cell carcinomas (OSCC). The aim of this work was to investigate the incidence of HPV infection in 40 paraffin-embedded or fresh specimens of OSCC, using PCR amplification of the viral DNA. Literature based primers (GP5+/GP6+) were used in order to amplify HPV DNA from the L1 gene, present in more than 22 types of HPV. A condyloma case with HPV 16 and 18 detected by in situ hybridization was used as a positive control. Amplification of HPV was observed only in the positive control. No squamous cell carcinoma cases showed DNA viral amplification. Absence of HPV DNA amplification by PCR in the analyzed specimens of OSCCs suggests that this virus not always plays a role in the carcinogenesis process. Discrepancy with some studies found in the literature may be related to methodology or population differences.


2007 ◽  
Vol 27 (6) ◽  
pp. 243-248 ◽  
Author(s):  
Yong-Kie Wong ◽  
Tsung-Yun Liu ◽  
Kuo-Wei Chang ◽  
Shu-Chun Lin ◽  
Tsurn-Waan Chao ◽  
...  

2019 ◽  
Vol 132 ◽  
pp. 38
Author(s):  
R. Waldram ◽  
A. Taylor ◽  
R. Prestwich ◽  
S. Whittam ◽  
L. Murray ◽  
...  

2000 ◽  
Vol 29 (4) ◽  
pp. 167-172 ◽  
Author(s):  
King Y. Lam ◽  
Irene O. L. Ng ◽  
Anthony P. W. Yuen ◽  
Dora L. W. Kwong ◽  
William Wei

2014 ◽  
Vol 44 (9) ◽  
pp. 693-698 ◽  
Author(s):  
Cho Ming Ho ◽  
Fang-Wei Hu ◽  
Shiuan-Shinn Lee ◽  
Tzong-Ming Shieh ◽  
Chuan-Hang Yu ◽  
...  

2017 ◽  
Vol 75 (6) ◽  
pp. 442-445 ◽  
Author(s):  
Hellevi M. A. Ruokonen ◽  
Aino Juurikivi ◽  
Timo Kauppila ◽  
Anna Maria Heikkinen ◽  
Riitta Seppänen-Kaijansinkko

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