Chinese herbal medicine Dengzhan Xixin injection for acute ischemic stroke: A systematic review and meta-analysis of randomised controlled trials

2017 ◽  
Vol 34 ◽  
pp. 74-85 ◽  
Author(s):  
Jin-gen Li ◽  
Li-qiong Wang ◽  
Xiao-ying Yang ◽  
Zhuo Chen ◽  
Lily Y.W. Lai ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-10
Author(s):  
Wenxiu Guo ◽  
Xiaoguang Lu ◽  
Dalong Wang ◽  
Tuo Chen ◽  
Zhiwei Fan ◽  
...  

Introduction. Although Chinese herbal medicine (CHM) treatment combined with conventional western therapy has been widely used and reported in many clinical trials in China, there is uncertainty about the efficacy of this combination in the treatment of patients after cardiopulmonary resuscitation (CPR). This systematic review aimed to assess whether the risk of mortality has decreased comparing the combination of CHM treatment with conventional western therapy.Methods. To identify relevant studies, the literature search was conducted in Medline, Embase, the Cochrane Library, CBM, CNKI, VIP, and Wanfang database. We included all randomized controlled trials (RCTs) that compared outcomes of patients after CPR taking combination of CHM treatment with those taking just conventional western therapy.Results. This meta-analysis showed that patients randomly assigned to combined CHM treatment group had a statistically significant 23% reduction in mortality compared with those randomly assigned to conventional western therapy group (RR: 0.77; 95% CI: 0.70–0.84).Conclusions. This meta-analysis provides evidence suggesting that a combined CHM therapy is associated with a decreased risk of mortality compared with conventional western therapy in patients after CPR. Further studies are needed to provide more evidence to prove or refute our conclusion and identify reasons for the reduction of mortality.


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