A gap-junction-mediated, calcium-signaling network controls blood progenitor fate decisions in hematopoiesis

2021 ◽  
Author(s):  
Kevin Y.L. Ho ◽  
Rohan J. Khadilkar ◽  
Rosalyn L. Carr ◽  
Guy Tanentzapf
Keyword(s):  
Calcium Signaling ◽  
Gap Junction ◽  
Signaling Network

scholarly journals Intercellular calcium signaling via gap junction in connexin-43-transfected cells.

1998 ◽  
Vol 273 (35) ◽  
pp. 22856
Author(s):  
Toshihiko Toyofuku ◽  
Masanori Yabuki ◽  
Kinya Otsu ◽  
Tsunehiko Kuzuya ◽  
Masatsugu Hori ◽  
...  
Keyword(s):  
Calcium Signaling ◽  
Gap Junction ◽  
Connexin 43 ◽  
Transfected Cells

Emerging roles of the CBL-CIPK calcium signaling network as key regulatory hub in plant nutrition

2021 ◽  
Vol 257 ◽  
pp. 153335
Author(s):  
Qiuyan Dong ◽  
Bowen Bai ◽  
Bader O. Almutairi ◽  
Jörg Kudla
Keyword(s):  
Calcium Signaling ◽  
Plant Nutrition ◽  
Signaling Network

Calcium Signaling Is Involved in EthanolInduced Volume Decrease and Gap Junction Closure in Cultured Rat Gastric Mucosal Cells

2005 ◽  
Vol 50 (1) ◽  
pp. 103-110 ◽  
Author(s):  
Harri Mustonen ◽  
Tuula Kiviluoto ◽  
Hannu Paimela ◽  
Pauli Puolakkainen ◽  
Eero Kivilaakso
Keyword(s):  
Calcium Signaling ◽  
Gap Junction ◽  
Gastric Mucosal Cells ◽  
Mucosal Cells ◽  
Volume Decrease

scholarly journals Intercellular calcium signaling in a gap junction-coupled cell network establishes asymmetric neuronal fates in C. elegans

Development ◽  
2012 ◽  
Vol 139 (22) ◽  
pp. 4191-4201 ◽  
Author(s):  
J. A. Schumacher ◽  
Y.-W. Hsieh ◽  
S. Chen ◽  
J. K. Pirri ◽  
M. J. Alkema ◽  
...  
Keyword(s):  
Calcium Signaling ◽  
Gap Junction ◽  
C Elegans ◽  
Cell Network

scholarly journals Intercellular Calcium Signaling via Gap Junction in Connexin-43-transfected Cells

1998 ◽  
Vol 273 (3) ◽  
pp. 1519-1528 ◽  
Author(s):  
Toshihiko Toyofuku ◽  
Masanori Yabuki ◽  
Kinya Otsu ◽  
Tsunehiko Kuzuya ◽  
Masatsugu Hori ◽  
...  
Keyword(s):  
Calcium Signaling ◽  
Gap Junction ◽  
Connexin 43 ◽  
Transfected Cells

scholarly journals Activation of L-type Calcium Channels Is Required for Gap Junction-mediated Intercellular Calcium Signaling in Osteoblastic Cells

2002 ◽  
Vol 278 (6) ◽  
pp. 4082-4086 ◽  
Author(s):  
Niklas Rye Jørgensen ◽  
Stefan Cuoni Teilmann ◽  
Zanne Henriksen ◽  
Roberto Civitelli ◽  
Ole Helmer Sørensen ◽  
...  
Keyword(s):  
Calcium Channels ◽  
Calcium Signaling ◽  
Gap Junction ◽  
Osteoblastic Cells

scholarly journals Functional implications of calcium permeability of the channel formed by pannexin 1

2006 ◽  
Vol 174 (4) ◽  
pp. 535-546 ◽  
Author(s):  
Fabien Vanden Abeele ◽  
Gabriel Bidaux ◽  
Dmitri Gordienko ◽  
Benjamin Beck ◽  
Yuri V. Panchin ◽  
...  
Keyword(s):  
Calcium Signaling ◽  
Gap Junction ◽  
Gap Junction Channels ◽  
Pannexin 1 ◽  
Signaling Mechanisms ◽  
Junction Molecules ◽  
Calcium Permeability ◽  
New Protein ◽  
Insight Into ◽  
Molecular Nature

Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca2+-permeable gap junction channels between adjacent cells, thus, allowing direct intercellular Ca2+ diffusion and facilitating intercellular Ca2+ wave propagation. More intriguingly, our results strongly suggest that PanX1 may also form Ca2+-permeable channels in the endoplasmic reticulum (ER). These channels contribute to the ER Ca2+ leak and thereby affect the ER Ca2+ load. Because leakage remains the most enigmatic of those processes involved in intracellular calcium homeostasis, and the molecular nature of the leak channels is as yet unknown, the results of this work provide new insight into calcium signaling mechanisms. These results imply that for vertebrates, a new protein family, referred to as pannexins, may not simply duplicate the connexin function but may also provide additional pathways for intra- and intercellular calcium signaling and homeostasis.

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