Origins of life: Encapsulating Darwinian evolution

2022 ◽  
Vol 32 (1) ◽  
pp. R44-R46
Author(s):  
Lorenzo Sebastianelli ◽  
Sheref S. Mansy
Keyword(s):  
Origins Of Life ◽  
Darwinian Evolution

scholarly journals Conceptualizing the origin of life in terms of evolution

2017 ◽  
Vol 375 (2109) ◽  
pp. 20160346 ◽  
Author(s):  
N. Takeuchi ◽  
P. Hogeweg ◽  
K. Kaneko
Keyword(s):  
Origin Of Life ◽  
Origins Of Life ◽  
Darwinian Evolution ◽  
Chemical System ◽  
Crucial Question ◽  
Opinion Piece ◽  
Ongoing Work ◽  
The Origin Of Life ◽  
Multi Level ◽  
Emergence Of Life

In this opinion piece, we discuss how to place evolution in the context of origin-of-life research. Our discussion starts with a popular definition: ‘life is a self-sustained chemical system capable of undergoing Darwinian evolution’. According to this definition, the origin of life is the same as the origin of evolution: evolution is the ‘end’ of the origin of life. This perspective, however, has a limitation, in that the ability of evolution in and of itself is insufficient to explain the origin of life as we know it, as indicated by Spiegelman’s and Lincoln and Joyce’s experiments. This limitation provokes a crucial question: What conditions are required for replicating systems to evolve into life? From this perspective, the origin of life includes the emergence of life through evolution: evolution is a ‘means’ of the origin of life. After reviewing Eigen’s pioneering work on this question, we mention our ongoing work suggesting that a key condition might be conflicting multi-level evolution. Taken together, there are thus two questions regarding the origin of life: how evolution gets started, and how evolution produces life. Evolution is, therefore, at the centre of the origin of life, where the two lines of enquiry must meet. This article is part of the themed issue ‘Reconceptualizing the origins of life’.

scholarly journals Critical events of the origins of life

2020 ◽  
Author(s):  
Caleb Deen Bastian ◽  
Herschel Rabitz
Keyword(s):  
Origins Of Life ◽  
Darwinian Evolution ◽  
Hitting Times ◽  
Sequence Specificity ◽  
Simulation Studies ◽  
Critical Events ◽  
Rna Molecules ◽  
Model And Simulation ◽  
Surface Chemistries ◽  
Directed Polymerization

AbstractWe discuss some critical events of the origins of life using a mathematical model and simulation studies. We find that for a replicating population of RNA molecules participating in template-directed polymerization, the hitting and establishment of a high-fidelity replicator depends critically on the polymerase fitness and sequence specificity landscapes and on genome dimension. Probability of hitting is dominated by polymerase landscape curvature, whereas hitting time is dominated by genome dimension. Surface chemistries, compartmentalization, and decay increase hitting times. These results suggest replication to be the first ‘privileged function’ marking the start of Darwinian evolution, possibly in conjunction with clay minerals or preceded by metabolism, whose dynamics evolved mostly during the final period of the search.

Chemical evolution of interstellar dust, comets and the origins of life

1989 ◽  
Vol 14 (2) ◽  
pp. 103-131 ◽  
Author(s):  
J. Mayo Greenberg ◽  
Nansheng Zhao ◽  
Joniek Hage
Keyword(s):  
Chemical Evolution ◽  
Interstellar Dust ◽  
Origins Of Life

Artificial Chemistry and Molecular Darwinian Evolution in silico

2003 ◽  
Vol 68 (1) ◽  
pp. 139-177 ◽  
Author(s):  
Vladimír Kvasnička ◽  
Jiří Pospíchal
Keyword(s):  
Graph Theory ◽  
Molecular Level ◽  
Stable State ◽  
Chemical Reactor ◽  
Darwinian Evolution ◽  
Simplified Model ◽  
Asymptotically Stable ◽  
Artificial Chemistry ◽  
Neutral Mutations ◽  
Binary Strings

A simplified model of Darwinian evolution at the molecular level is studied by applying the methods of artificial chemistry. A chemical reactor (chemostat) contains molecules that are represented by binary strings, the strings being capable of replication with a probability proportional to their fitness. Moreover, the process of replication is not fully precise, sporadic mutations may produce new offspring strings, which are slightly different from their parent templates. The dynamics of such an autoreplicating system is described by Eigen's differential equations. These equations have a unique asymptotically stable state, which corresponds to those strings that have the highest rate constants (fitness). Fitness of binary string is calculated as a graph-theory similarity between a folding (phenotype) of respective string and the so-called required folding. The presented method offers a detailed view of mechanisms of the molecular Darwinian evolution, in particular of the meaning and importance of neutral mutations.

The Modernity of Kinship

2018 ◽  
Author(s):  
Hans Hummer
Keyword(s):  
Nineteenth Century ◽  
Building Block ◽  
Darwinian Evolution ◽  
Evolutionary Development ◽  
European Studies ◽  
The West ◽  
Elemental Form

Chapter 1 explores the modern values that have animated kinship studies since their emergence in the nineteenth century. It examines the sudden invention of kinship by Johann Bachofen, Henry Maine, John Ferguson McLennan, Numa Denis Fustel de Coulanges, and Lewis Henry Morgan in the 1860s, and the internal and external developments in the West that prompted their discoveries: revolutionary agitation, the engagement with “primitives” around the globe, industrialization and the disintegration of old solidarities, and intellectual revolutions in the study of prehistory, especially Indo-European studies and Darwinian evolution. Social theorists transformed kinship into an elemental form of human sociality and evolutionary development, and a building block of the emerging liberal order as the West coped with the ontological sea change wrought by the desacralization and industrialization of society.

Prebiotic studies on the interaction of zirconia nanoparticles and ribose nucleotides and their role in chemical evolution

2021 ◽  
Vol 20 (2) ◽  
pp. 142-149
Author(s):  
Avnish Kumar Arora ◽  
Pankaj Kumar
Keyword(s):  
Electron Microscopy ◽  
Metal Oxide ◽  
Metal Oxides ◽  
Chemical Evolution ◽  
Ribonucleic Acid ◽  
Zirconium Oxide ◽  
Origins Of Life ◽  
Neutral Ph ◽  
Interaction Studies

AbstractStudies on the interaction of biomolecules with inorganic compounds, mainly mineral surfaces, are of great concern in identifying their role in chemical evolution and origins of life. Metal oxides are the major constituents of earth and earth-like planets. Hence, studies on the interaction of biomolecules with these minerals are the point of concern for the study of the emergence of life on different planets. Zirconium oxide is one of the metal oxides present in earth's crust as it is a part of several types of rocks found in sandy areas such as beaches and riverbeds, e.g. pebbles of baddeleyite. Different metal oxides have been studied for their role in chemical evolution but no studies have been reported about the role of zirconium oxide in chemical evolution and origins of life. Therefore, studies were carried out on the interaction of ribonucleic acid constituents, 5′-CMP (cytidine monophosphate), 5′-UMP (uridine monophosphate), 5′-GMP (guanosine monophosphate) and 5′-AMP (adenosine monophosphate), with zirconium oxide. Synthesized zirconium oxide particles were characterized by using vibrating sample magnetometer, X-Ray Diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy. Zirconia particles were in the nanometre range, from 14 to 27 nm. The interaction of zirconium oxide with ribonucleic acid constituents was performed in the concentration range of 5 × 10−5–300 × 10−5 M. Interaction studies were carried out in three mediums; acidic (pH 4.0), neutral (pH 7.0) and basic (pH 9.0). At neutral pH, maximum interaction was observed. The interaction of zirconium oxide with 5′-UMP was 49.45% and with 5′-CMP 67.98%, while with others it was in between. Interaction studies were Langmurian in nature. Xm and KL values were calculated. Infrared spectral studies of ribonucleotides, metal oxide and ribonucleotide–metal oxide adducts were carried out to find out the interactive sites. It was observed that the nitrogen base and phosphate moiety of ribonucleotides interact with the positive charge surface of metal oxide. SEM was also carried out to study the adsorption. The results of the present study favour the important role of zirconium oxide in concentrating the organic molecules from their dilute aqueous solutions in primeval seas.

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