scholarly journals The BAR Domain Protein Arfaptin-1 Controls Secretory Granule Biogenesis at the trans-Golgi Network

2012 ◽  
Vol 23 (4) ◽  
pp. 756-768 ◽  
Author(s):  
Helmuth Gehart ◽  
Alexander Goginashvili ◽  
Rainer Beck ◽  
Joëlle Morvan ◽  
Eric Erbs ◽  
...  
Keyword(s):  
Secretory Granule ◽  
Bar Domain ◽  
Trans Golgi Network ◽  
Domain Protein ◽  
Golgi Network

Dense-Core Secretory Granule Biogenesis

Physiology ◽  
2006 ◽  
Vol 21 (2) ◽  
pp. 124-133 ◽  
Author(s):  
Taeyoon Kim ◽  
Marjorie C. Gondré-Lewis ◽  
Irina Arnaoutova ◽  
Y. Peng Loh
Keyword(s):  
Secretory Granule ◽  
Endocrine Cells ◽  
Dense Core ◽  
Trans Golgi Network ◽  
Golgi Network

The dense-core secretory granule is a key organelle for secretion of hormones and neuropeptides in endocrine cells and neurons, in response to stimulation. Cholesterol and granins are critical for the assembly of these organelles at the trans-Golgi network, and their biogenesis is regulated quantitatively by posttranscriptional and posttranslational mechanisms.

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