<b>Introduction: </b>Difficulty
achieving preset goals (e.g., ≥5% weight loss, ≥150 minutes of weekly physical
activity) in the yearlong National Diabetes Prevention Program (NDPP) can prompt dropout and diminish benefits. We piloted a more patient-centered NDPP adaptation
(NDPP-Flex) that promotes a variety of attainable and individually-tailored goals to reduce diabetes
risks, along with flexibility to adjust goals each
week as needed.
<p><b>Research Design and Methods: </b>Retention,
physical activity, weight, and HbA1c were evaluated among diverse participants
with diabetes risks who received our pilot of
NDPP-Flex beginning in January and July 2018 (<i>n</i>=95), with a planned
comparison to standard NDPP delivery in preceding cohorts that launched between
September 2016 and October 2017 (<i>n</i>=245).
Both the standard NDPP and NDPP-Flex interventions were one year in duration
and implemented in phases (i.e., non-randomized). </p>
<p><b>Results: </b>Average
adjusted retention (e.g., 158.90 ± 15.20 vs. 166.71 ± 9.38 days; <i>P</i>=.674),
physical activity (157.97 ± 11.91 vs. 175.64 ± 7.54 weekly minutes; <i>P</i>=.231),
and weight loss (1.46 ± 0.38% vs. 1.90 ± 0.24%; <i>P</i>=.396) were similar between
NDPP-Flex versus standard NDPP. However, NDPP-Flex
participants had greater HbA1c reduction on average (0.22 ± 0.05% vs. 0.06 ±
0.03%, <i>P</i>=.018) and were more likely to have normoglycemia at follow-up
(OR 4.62; <i>P</i>=.013; 95% CI 1.38-15.50) than participants in the standard
NDPP. </p>
<p><b>Conclusions: </b>An adapted, more patient-centered NDPP that focuses on flexible, self-selected
goals may be a promising strategy to improve glycemia even in the absence of substantial
weight loss.<b></b></p>
Effectiveness of Financial Incentives in a Worksite Diabetes Prevention Program
