The prevalence of undiagnosed type 2 diabetes and prediabetes in Eastern Mediterranean region (EMRO): A systematic review and meta-analysis

2020 ◽  
Vol 160 ◽  
pp. 107931 ◽  
Author(s):  
Alireza Mirahmadizadeh ◽  
Mohammad Fathalipour ◽  
Ali Mohammad Mokhtari ◽  
Shahryar Zeighami ◽  
Soheil Hassanipour ◽  
...  
2020 ◽  
Author(s):  
Reza Negarandeh ◽  
Shah Jahan Shayan ◽  
Rajab Nazari ◽  
BSc. Frank Kiwanuka ◽  
MSc. Sanaz Akhavan Rad

Abstract Background Recently, inappropriate use of antibiotics has been correlated with life-threatening side-effects such as adverse effects, increased cost of treatment, and the higher rate of microbial resistance. Besides, it leads to a waste of resources. Therefore, this review sought to determine the pooled prevalence of self-medication with antibiotics, self-medicated illness, reasons for self-medication, antibiotics used for self-medication, source of obtaining antibiotics, the inappropriate practice of antibiotics and suggested recommendations for talking self-medication with antibiotics in the Eastern Mediterranean Region of the World Health Organization (EMRWHO). Methods Review conforms to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement. Database search was conducted in PubMed, Scopus, Embase, and Web of Science using a combination of keywords which included; antimicrobial, antibacterial, antibiotic, self-medication, self-treatment, self-prescription, non-prescribed, irrational use, inappropriate use, misuse, abuse and Eastern Mediterranean Region of WHO countries. The lists of references of the selected articles were also hand-searched to obtained additional relevant articles. Studies published in English from 2000 to 2018 were included in the review. Results We report on data from 60 articles and 49629 participants in this review. The overall prevalence of self-medication with antibiotics in EMRWHO was 47.2% (95% CI 41.6% – 52.9%). Yemen has the highest pooled rate with a rate of 75.0% (95% CI 63.4% − 83.9%), whilst Lebanon has the lowest pooled rate with a prevalence of 28.7% (95% CI 18.4% − 41.8%). The most common illnesses implicated in antibiotic self-medication were upper-respiratory infections and the most common antibiotic was Amoxicillin-Clavulanic acid. The commonest reasons for antibiotic self-medication include: saving time and money. Pharmacies pointed out as the most common source of obtaining antibiotics for self-medication. Conclusion Self-medication with antibiotics is significantly high in the member states of EMRWHO. Intervention such as an educational program for communities’ members to change their behaviors, policy on the mechanism of distribution of antibiotics is called for in this area.


2019 ◽  
Vol 51 (10) ◽  
pp. 719-729
Author(s):  
Abdulbaset Maleknejad ◽  
Neda Dastyar ◽  
Mahin Badakhsh ◽  
Abbas Balouchi ◽  
Hosein Rafiemanesh ◽  
...  

Endocrine ◽  
2019 ◽  
Vol 65 (3) ◽  
pp. 505-514 ◽  
Author(s):  
Mahin Badakhsh ◽  
Fereshteh Daneshi ◽  
Mahnaz Abavisani ◽  
Hosien Rafiemanesh ◽  
Salehoddin Bouya ◽  
...  

2020 ◽  
Author(s):  
Hamid Ravaghi ◽  
Mahnaz Afshari ◽  
parvaneh Isfahani ◽  
Alireza Mahboubahari ◽  
Victoria D Belorgeot

Abstract Background: Recent rising costs and shortages of healthcare resources make it necessary to address the issue of hospital efficiency. Increasing the efficiency of hospitals can result in better and sustainable achievement of their organizational goals.The purpose of the present research is to examine hospital efficiency in the Eastern Mediterranean Region (EMR).Methods: This study is a systematic review and meta-analysis of all articles published on hospital efficiency in Eastern Mediterranean countries between January 1999 and May 2018, identified by searching three databases (PubMed through MEDLINE, Web of Science, and Embase) and two search engines (Google and Google Scholar). The reference lists of these articles were checked for additional relevant studies. Fifty articles were finally selected, and data was analyzed through the Comprehensive Meta-Analysis Software (v.2.2.064). Results: Using the random-effects model, the mean hospital efficiency in Eastern Mediterranean hospitals was 0.829 ± 0.026 at 95% CI. Three approaches were used to measure hospital efficiency: data envelope analysis (DEA), stochastic frontier analysis (SFA), and Pabón Lasso Analysis. Different mean and standard deviation values were obtained from DEA (0.428±0.024), DEA and Pabón Lasso Analysis (0.925±0.029), Pabón Lasso Analysis (0.790±0.086) and SFA (0.594±0.056), due to the different inputs and outputs used in these methods. Technical efficiency (TE) was higher in some countries such as Iraq (0.976±0.035), Oman (0.926 ± 0.032), Jordan (0.924±0.060) and Saudi Arabia (0.917±0.023). Conclusion: Efficiency plays a significant role in hospital growth and development. It is therefore important for healthcare managers and policymakers in the EMR to identify the causes of inefficiency, to improve TE and develop cost-effective strategies.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Razieh Zahedi ◽  
Hossein Molavi Vardanjani ◽  
Mohammad Reza Baneshi ◽  
Ali Akbar Haghdoost ◽  
Reza Malekpour Afshar ◽  
...  

2021 ◽  
Author(s):  
Shahryar Zeighami ◽  
Sonia Shaabani ◽  
Mohammad Moheb ◽  
Maryam Pakfetrat ◽  
Seyede Pegah Azarchehry ◽  
...  

Abstract Objectives: The high prevalence of diabetes leads to an increase in diabetic complications, and diabetic nephropathy as one them is a leading cause of end stage renal disease and renal replacement therapies. Individual studies on the prevalence diabetic nephropathy in Eastern Mediterranean region (EMR) showed the high prevalence of diabetic nephropathy. Therefore, we conducted a systematic review and meta-analysis of relevant studies to estimate nephropathy among type two diabetes patients in EMR. Method: We searched for the relevant keywords in title and abstract of Medline/PubMed, Scopus, Embase, and Web of knowledge, as well as Google Scholar and manual search to identify the published target studies from Jan 1st, 2000 to December 13, 2020. The two-step screening was carried out by two independent researchers and relevant data were extracted. Estimation of summary proportions, subgroup analysis, meta-regressions, and publication bias assessment were performed.Results: Amongst 3225 identified citations, 38 articles were entered into meta-analysis, involving 112,235 patients. We found that the prevalence of nephropathy in type two diabetes was 26.34% (95% confidence interval (CI)= 21.04%, 32%). Prevalence of nephropathy was 30.42% (95% CI= 23.38%, 37.94%) in males 22.1% (95% CI= 16.05%, 28.79%) in females. Low HDI countries and very high HDI countries had the lowest (21.17% (95% CI= 1.1%, 56.22%)) and the highest (30.93% (95% CI= 22.16%, 40.44%)) prevalence rates. The meta-regression analysis showed that HDI, publication year, mean duration of diabetes, mean age, and diagnostic test were not significant moderators (p = .3323, .7247, .2802, .2199, and .4680, respectively).Conclusions: We estimated a high prevalence of diabetic nephropathy in EMR. Our results implicate the importance of diabetes screening, on time and periodic examinations for nephropathy, diabetes care, and risk factor controls. Large-scale longitudinal studies should be conducted in EMR.


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