Solitary Peutz–Jeghers type hamartomatous polyp in the transverse colon of an adolescent with ulcerative colitis

Barium enema and colonoscopy are contraindicated in severe attacks of ulcerative colitis because of the possibility of toxic megacolon and perforation. The authors have assessed abdominal ultrasound in 38 patients with severe ulcerative colitis. Ultrasound revealed bowel wall thicknesses ranging from 3.9 to 9.2 mm (mean 7.7) extending the whole length of the colon, to the transverse colon, and to the descending colon, respectively, in 18, 10 and eight patients. The degree of bowel thickening was related to the severity of inflammation based on clinical, sigmoidoscopic and histological evaluation. In two patients, ultrasound showed a thin bowel wall distended without motility, suggesting the diagnosis of toxic megacolon (confirmed radiologically). An excellent correlation (95%) was found between ultrasound and technetium-99 scanning. Ultrasound might be a reasonable first investigation in the assessment of patients with severe ulcerative colitis.

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A Rare Case of Signet Cell Carcinoma of Transverse Colon in a Young Patient With Ulcerative Colitis

Journal of Medical Cases ◽

10.14740/jmc3469 ◽

2020 ◽

Vol 11 (5) ◽

pp. 135-139

Author(s):

Mujtaba Mohamed ◽

Alsadiq Al Hillan ◽

Eugene Zurkovsky ◽

Min Zheng ◽

Arif Asif ◽

...

Keyword(s):

Ulcerative Colitis ◽

Cell Carcinoma ◽

Young Patient ◽

Transverse Colon ◽

Rare Case ◽

Signet Cell

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Two Cases of Severe Ulcerative Colitis with Colonic Dilatation Resolved with Tacrolimus Therapy

Case Reports in Gastroenterology ◽

10.1159/000438784 ◽

2015 ◽

Vol 9 (2) ◽

pp. 272-277

Author(s):

Ryohei Hayashi ◽

Yoshitaka Ueno ◽

Shinji Tanaka ◽

Shintaro Sagami ◽

Kenta Nagai ◽

...

Keyword(s):

Ulcerative Colitis ◽

Abdominal Pain ◽

Corticosteroid Therapy ◽

Transverse Colon ◽

Intestinal Tract ◽

Rescue Therapy ◽

Severe Ulcerative Colitis ◽

X Ray ◽

Emergency Colectomy ◽

Tacrolimus Therapy

We report 2 cases of ulcerative colitis (UC) with intestinal tract dilatation treated with tacrolimus. They were 53- and 64-year-old males, who had been admitted to local hospitals for increasing severity of their UC symptoms. Treatment for severe UC was immediately started, but both cases were refractory to corticosteroid therapy; they were then transferred to our hospital. When they were referred to our hospital, they had frequent bloody diarrhea, fever, severe abdominal pain, and even dilatation of the transverse colon on abdominal X-ray test. They were treated with oral tacrolimus medication, and their symptoms improved immediately. Dilatation of the transverse colon was improved on plain X-ray at 2 weeks after starting therapy, and emergency colectomy could be avoided. These 2 cases may suggest that tacrolimus is effective for UC with colonic dilatation as a rescue therapy.

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Colon

Mayo Clinic General Surgery ◽

10.1093/med/9780190650506.003.0005 ◽

2020 ◽

pp. 61-76

Author(s):

Jad M. Abdelsattar ◽

Moustafa M. El Khatib ◽

T. K. Pandian ◽

Samuel J. Allen ◽

David R. Farley

Keyword(s):

Colorectal Cancer ◽

Ulcerative Colitis ◽

Differential Diagnosis ◽

Diverticular Disease ◽

Surgical Resection ◽

Crohn Disease ◽

Transverse Colon ◽

Postoperative Bleeding ◽

Disease Treatment ◽

Ileocecal Junction

The colon is made up of the midgut which includes the proximal two-thirds of the transverse colon, and the hindgut, which includes the distal one-third of the transverse colon. The ileocecal junction to the anus is a distance of 1.5 m. Digested food (chyme) passes into the colon and is converted to feces by bacteria. The differential diagnosis of colonic masses includes cancer, carcinoid, lipoma, diverticular disease, ulcerative colitis, polyps, and Crohn disease. Treatment of colorectal cancer and symptomatic inflammatory colon disease usually involves wide surgical resection. Complications after surgery may include postoperative bleeding, leakage, and ileus.

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