Lack of estrogenic and anti-estrogenic activity of aromatic amines and their hydroxylated and acetylated metabolites on human breast cancer cells

2018 ◽  
Vol 33 (1) ◽  
pp. S66
Author(s):  
Linh Chi Bui ◽  
Kevin Cariou ◽  
Gautier Moroy ◽  
Jean-Marie Dupret ◽  
Fernando Rodrigues-Lima
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Aromatic Amines ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Estrogenic Activity ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Acetylated Metabolites

Estrogen Activities and the Cellular Effects of Natural Progesterone from Wild Yam Extract in MCF-7 Human Breast Cancer Cells

2009 ◽  
Vol 37 (01) ◽  
pp. 159-167 ◽  
Author(s):  
Mi-Kyung Park ◽  
Hyeok-Yi Kwon ◽  
Woong-Shick Ahn ◽  
Sumi Bae ◽  
Mee-Ra Rhyu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Estrogenic Activity ◽  
Mrna Levels ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Wild Yam ◽  
Mcf 7

We studied the estrogenic activity and cellular effect of wild yam extract in MCF-7 human breast cancer cells. The extract increased the activity of the progesterone receptor and pS2 genes at the mRNA levels in human breast cancer MCF-7 cells, although the effects were not as prominent as those of 17β-estradiol (E2). Western blot analysis showed that the level of estrogen receptor α protein was down-regulated after treatment with E2 or wild yam extract. Wild yam extract also inhibited proliferation of MCF-7 cells. These data indicate that wild yam extract acts as a weak phytoestrogen and protects against proliferation in human breast carcinoma MCF-7 cells.

scholarly journals Estrogenic Activity of Hyperforin in MCF-7 Human Breast Cancer Cells Transfected with Estrogen Receptor

Planta Medica ◽  
2016 ◽  
Vol 82 (16) ◽  
pp. 1425-1430 ◽  
Author(s):  
Joseph Kwon ◽  
Kyung Oh ◽  
Se-Young Cho ◽  
Mi Bang ◽  
Hwan Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Estrogenic Activity ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Mcf 7
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