ABT-888 and quinacrine induced apoptosis in metastatic breast cancer stem cells by inhibiting base excision repair via adenomatous polyposis coli

10.1016/j.dnarep.2016.05.034 ◽

2016 ◽

Vol 45 ◽

pp. 44-55 ◽

Author(s):

Sumit Siddharth ◽

Deepika Nayak ◽

Anmada Nayak ◽

Sarita Das ◽

Chanakya Nath Kundu

Keyword(s):

Breast Cancer ◽

Base Excision Repair ◽

Excision Repair ◽

Metastatic Breast ◽

Breast Cancer Stem Cells ◽

Adenomatous Polyposis ◽

Polyposis Coli ◽

Base Excision ◽

Induced Apoptosis

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Assembly of the Base Excision Repair Complex on Abasic DNA and Role of Adenomatous Polyposis Coli on Its Functional Activity

Biochemistry ◽

10.1021/bi102000q ◽

2011 ◽

Vol 50 (11) ◽

pp. 1901-1909 ◽

Author(s):

Aruna S. Jaiswal ◽

Satya Narayan

Keyword(s):

Adenomatous Polyposis Coli ◽

Base Excision Repair ◽

Functional Activity ◽

Excision Repair ◽

Adenomatous Polyposis ◽

Polyposis Coli ◽

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Molecular mechanism of adenomatous polyposis coli-induced blockade of base excision repair pathway in colorectal carcinogenesis

Life Sciences ◽

10.1016/j.lfs.2015.08.019 ◽

2015 ◽

Vol 139 ◽

pp. 145-152 ◽

Author(s):

Satya Narayan ◽

Ritika Sharma

Keyword(s):

Molecular Mechanism ◽

Adenomatous Polyposis Coli ◽

Base Excision Repair ◽

Excision Repair ◽

Colorectal Carcinogenesis ◽

Adenomatous Polyposis ◽

Repair Pathway ◽

Polyposis Coli ◽

Base Excision Repair Pathway ◽

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PARP inhibitor BMN-673 induced apoptosis by trapping PARP-1 and inhibiting base excision repair via modulation of Pol-β in chromatin of breast cancer cells

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2021.115860 ◽

2022 ◽

pp. 115860

Author(s):

Chinmayee Sethy ◽

Chanakya Nath Kundu

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Base Excision Repair ◽

Breast Cancer Cells ◽

Excision Repair ◽

Parp Inhibitor ◽

Base Excision ◽

Induced Apoptosis ◽

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Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: implication of base excision repair pathways

Carcinogenesis ◽

10.1093/carcin/bgm125 ◽

2007 ◽

Vol 28 (10) ◽

pp. 2089-2095 ◽

Author(s):

C. N. Kundu ◽

R. Balusu ◽

A. S. Jaiswal ◽

S. Narayan

Keyword(s):

Base Excision Repair ◽

Excision Repair ◽

Fibroblast Cell ◽

Mouse Embryonic Fibroblast ◽

Adenomatous Polyposis ◽

Polyposis Coli ◽

Mouse Embryonic Fibroblast Cell ◽

Base Excision ◽

Embryonic Fibroblast ◽

Fibroblast Cell Lines

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Structure/Function Analysis of the Interaction of Adenomatous Polyposis Coli with DNA Polymerase β and Its Implications for Base Excision Repair†

Biochemistry ◽

10.1021/bi701632e ◽

2007 ◽

Vol 46 (49) ◽

pp. 13961-13974 ◽

Author(s):

Ramesh Balusu ◽

Aruna S. Jaiswal ◽

Melissa L. Armas ◽

Chanakya N. Kundu ◽

Linda B. Bloom ◽

...

Keyword(s):

Structure Function ◽

Adenomatous Polyposis Coli ◽

Dna Polymerase ◽

Base Excision Repair ◽

Excision Repair ◽

Function Analysis ◽

Adenomatous Polyposis ◽

Polyposis Coli ◽

Dna Polymerase Β ◽

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Mechanism of Adenomatous Polyposis Coli (APC)-Mediated Blockage of Long-Patch Base Excision Repair†

Biochemistry ◽

10.1021/bi0607958 ◽

2006 ◽

Vol 45 (51) ◽

pp. 15903-15914 ◽

Author(s):

Aruna S. Jaiswal ◽

Ramesh Balusu ◽

Melissa L. Armas ◽

Chanakya N. Kundu ◽

Satya Narayan

Keyword(s):

Adenomatous Polyposis Coli ◽

Base Excision Repair ◽

Excision Repair ◽

Adenomatous Polyposis ◽

Polyposis Coli ◽

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5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway

10.1016/j.dnarep.2014.10.006 ◽

2014 ◽

Vol 24 ◽

pp. 15-25 ◽

Author(s):

Dipon Das ◽

Ranjan Preet ◽

Purusottam Mohapatra ◽

Shakti Ranjan Satapathy ◽

Sumit Siddharth ◽

...

Keyword(s):

Colon Cancer ◽

Base Excision Repair ◽

Excision Repair ◽

Adenomatous Polyposis ◽

Colon Cancer Cells ◽

Repair Pathway ◽

Polyposis Coli ◽

Anti Cancer ◽

Base Excision ◽

Cancer Activity

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Cigarette smoke condensate-induced level of adenomatous polyposis coli blocks long-patch base excision repair in breast epithelial cells

Oncogene ◽

10.1038/sj.onc.1209925 ◽

2006 ◽

Vol 26 (10) ◽

pp. 1428-1438 ◽

Author(s):

C N Kundu ◽

R Balusu ◽

A S Jaiswal ◽

C G Gairola ◽

S Narayan

Keyword(s):

Epithelial Cells ◽

Cigarette Smoke ◽

Adenomatous Polyposis Coli ◽

Base Excision Repair ◽

Excision Repair ◽

Adenomatous Polyposis ◽

Cigarette Smoke Condensate ◽

Polyposis Coli ◽

Breast Epithelial Cells ◽

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CLINICAL IMPACT OF BREAST CANCER STEM CELLS IN METASTATIC BREAST CANCER PATIENTS

10.1016/s0960-9776(19)30667-8 ◽

2019 ◽

Vol 48 ◽

pp. S42-S43

Author(s):

Mohamed Elbaiomy ◽

Tamer Akl ◽

Ahmed Elsayeid

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Cancer Stem Cells ◽

Cancer Patients ◽

Metastatic Breast ◽

Clinical Impact ◽

Breast Cancer Stem Cells ◽

Breast Cancer Patients

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Decrease in Abundance of Apurinic/Apyrimidinic Endonuclease Causes Failure of Base Excision Repair in Culture-Adapted Human Embryonic Stem Cells

10.1002/stem.1312 ◽

2013 ◽

Vol 31 (4) ◽

pp. 693-702 ◽

Author(s):

Miriama Krutá ◽

Lukáš Bálek ◽

Renata Hejnová ◽

Zuzana Dobšáková ◽

Livia Eiselleová ◽

...

Keyword(s):

Embryonic Stem Cells ◽

Base Excision Repair ◽

Human Embryonic Stem Cells ◽

Excision Repair ◽

Embryonic Stem ◽

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