scholarly journals Effects of anterior thalamic nuclei stimulation on hippocampal activity: chronic recording in a patient with drug-resistant focal epilepsy

2021 ◽  
pp. 100467
Author(s):  
Alexander B. Silva ◽  
Ankit N. Khambhati ◽  
Benjamin A. Speidel ◽  
Edward F. Chang ◽  
Vikram R. Rao
Keyword(s):  
Focal Epilepsy ◽  
Drug Resistant ◽  
Thalamic Nuclei ◽  
Chronic Recording ◽  
Hippocampal Activity ◽  
Anterior Thalamic Nuclei

Headache Perception in an Epilepsy Patient with Neuromodulation by Anterior Thalamic Nuclei Deep Brain Stimulation: A Case Report

2020 ◽  
Vol 81 (04) ◽  
pp. 368-371
Author(s):  
Bogdan Pintea ◽  
Rainer Surges ◽  
Jan Boström
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Chronic Headache ◽  
Pain Perception ◽  
Focal Epilepsy ◽  
Thalamic Nuclei ◽  
Pain Anxiety ◽  
Anterior Thalamic Nuclei ◽  
Pain Anxiety Symptoms Scale ◽  
Deep Brain

Abstract Objective Headache disorders are frequently associated with epilepsy. Some neuromodulation techniques for refractory epilepsy have been reported to positively influence the associated chronic headache. However, the exact mechanism of action of vagus nerve stimulation (VNS) and anterior thalamic nuclei-deep brain stimulation (ANT-DBS) on pain perception is unclear. Method We report a structured assessment of pain perception in a patient who experienced headache relief after ANT-DBS for refractory focal epilepsy and compare it with pain perception of epilepsy patients with chronic headache who were treated with and without VNS. Results The pain-associated symptoms in the ANT-DBS case were on the Pain Anxiety Symptoms Scale (PASS-40) subscore “physiological anxiety” closer to the control collective, whereas in patients with VNS, this was more likely for the PASS-40 subscores “cognitive anxiety” or “escape and avoidance.” Conclusion ANT-DBS and VNS may influence epilepsy-associated chronic headache in different ways.

Eslicarbazepine acetate add-on therapy for drug-resistant focal epilepsy

2021 ◽  
Vol 2021 (6) ◽  
Author(s):  
Xian-Chao Chang ◽  
Hai Yuan ◽  
Yi Wang ◽  
Hui-Qin Xu ◽  
Wen-Ke Hong ◽  
...  
Keyword(s):  
Focal Epilepsy ◽  
Drug Resistant ◽  
Eslicarbazepine Acetate

Valproate add-on therapy for drug-resistant focal epilepsy

2021 ◽  
Vol 2021 (7) ◽  
Author(s):  
Myrsini Gianatsi ◽  
Rebecca Bresnahan ◽  
Ruaraidh A Hill ◽  
Sarah J Nevitt ◽  
Anthony G Marson ◽  
...  
Keyword(s):  
Focal Epilepsy ◽  
Drug Resistant

scholarly journals Molecular diagnostics in drug‐resistant focal epilepsy define new disease entities

2021 ◽  
Vol 31 (4) ◽  
Author(s):  
Katja Kobow ◽  
Stéphanie Baulac ◽  
Andreas Deimling ◽  
Jeong Ho Lee
Keyword(s):  
Molecular Diagnostics ◽  
Focal Epilepsy ◽  
Drug Resistant ◽  
New Disease ◽  
Disease Entities

scholarly journals Gabapentin add-on treatment for drug-resistant focal epilepsy

2021 ◽  
Author(s):  
Mariangela Panebianco ◽  
Sarah Al-Bachari ◽  
Jane L Hutton ◽  
Anthony G Marson
Keyword(s):  
Focal Epilepsy ◽  
Drug Resistant
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