scholarly journals Examining health-related quality of life in pediatric cancer patients with febrile neutropenia: Factors predicting poor recovery in children and their parents

2021 ◽  
pp. 101095
Author(s):  
Anna Crothers ◽  
Gabrielle M Haeusler ◽  
Monica A Slavin ◽  
Franz E Babl ◽  
Francoise Mechinaud ◽  
...  
Author(s):  
Amal Hegazy ◽  
Hussain Al Bar ◽  
Sultan H. Alamri ◽  
Fatimah Ahmad Almahmoudi ◽  
Wafa Saleh Al Ghamdi ◽  
...  

Background: In recent years the survival rates for children diagnosed with cancer has increased as result of successful treatment. Evaluation of health related quality of life during the process of treatments is important for recognition of acute dysfunction related to therapy and disease. Aim: Aim of the study is to identify the health-related quality of life in pediatric cancer patients and to detect the potential predictors of a total quality of life and its domains. Materials and Methods: It is a cross-sectional study done on convenient sample of pediatric cancer patients. Their diagnosis was confirmed at pediatric hematology clinic and day care unit at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Results: A total number of 51 children participated in this study, their age ranging from 8-15 years with mean 10.15± 2.52. Hematological malignancies represented 70.5% of the sample, with the highest percentage for acute lymphocytic leukemia (45%). The mean value of the total quality of life is 73.48, which is referred to as a good quality of life. The best scores of subscales were cognitive problems (92.54), communication (82.67), and nausea (76.86), otherwise poorer score was detected. Although the value of total quality of life was relatively good however visiting the hospital more than 3 times per month, male gender, duration of therapy and duration of diagnosis more associated with more pain and hurt, great worry and treatment anxiety. Conclusion: Higher frequency of hospital visits, male gender, longer duration of diagnosis, longer duration of therapy, and increased intensity of therapy were all associated with more pain and hurt, great worry, nausea, and treatment anxiety which reflect a poor quality of life among the study group.


2003 ◽  
Vol 32 (3) ◽  
pp. 215-232 ◽  
Author(s):  
Maru Barrera ◽  
Leigh-Ann Wayland ◽  
Norma M. D'Agostino ◽  
Julie Gibson ◽  
Rosanna Weksberg ◽  
...  

Author(s):  
Hester.R. Trompetter ◽  
Cynthia S. Bonhof ◽  
Lonneke V. van de Poll-Franse ◽  
Gerard Vreugdenhil ◽  
Floortje Mols

Abstract Purpose Chemotherapy-induced peripheral neuropathy ((CI)PN) becomes chronic in 30% of cancer patients. Knowledge of predictors of chronic (CI)PN and related impairments in health-related quality of life (HRQoL) is lacking. We examined the role of optimism in chronic (CI)PN severity and associated HRQoL in colorectal cancer (CRC) patients up to two years after diagnosis. Methods CRC patients from a prospective cohort study participated, with sensory peripheral neuropathy (SPN) 1 year after diagnosis (n = 142). Multivariable regression analyses examined the cross-sectional association between optimism (measured by the LOT-R) and SPN severity/HRQoL (measured by the EORTC QLQ-CIPN20 and QLQ-C30), as well as the prospective association in a subsample that completed measures 2 years after diagnosis and still experienced SPN (n = 86). Results At 1-year follow-up, higher optimism was associated with better global HRQoL, and better physical, role, emotional, cognitive, and social functioning (all p < .01). Optimism at year one was also prospectively associated with better global HRQoL (p < .05), and emotional and cognitive functioning at 2-year follow-up (both p < .01). Optimism was not related to self-reported SPN severity. Significant associations were retained when controlling for demographic/clinical variables, and became non-significant after controlling for depressive and anxiety symptoms. Conclusions Optimism and depressive and anxiety symptoms are associated with HRQoL in CRC patients with chronic (CI)PN. Future research may illuminate the mechanisms that these factors share, like the use of (non)adaptive coping styles such as avoidance and acceptance that may inform the design of targeted interventions to help patients to adapt to chronic (CI)PN.


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