Prognostic value of lymphovascular invasion in women with lymph node negative invasive breast carcinoma

2006 ◽  
Vol 42 (3) ◽  
pp. 357-362 ◽  
Author(s):  
A.H.S. Lee ◽  
S.E. Pinder ◽  
R.D. Macmillan ◽  
M. Mitchell ◽  
I.O. Ellis ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Prognostic Value ◽  
Lymphovascular Invasion ◽  
Invasive Breast Carcinoma ◽  
Node Negative

scholarly journals The prognostic value of p53 and c-erb b-2 immunostaining is overrated for patients with lymph node negative breast carcinoma

Cancer ◽  
2000 ◽  
Vol 88 (4) ◽  
pp. 804-813 ◽  
Author(s):  
Wenche Reed ◽  
Einar Hannisdal ◽  
Per Johannes Boehler ◽  
Stein Gundersen ◽  
Herman Host ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Prognostic Value ◽  
Node Negative

scholarly journals Lymph node negative invasive breast carcinoma 1 centimeter or less in size (T1a,bN0M0)

Cancer ◽  
1997 ◽  
Vol 79 (4) ◽  
pp. 761-771 ◽  
Author(s):  
Arthur K.�C. Lee ◽  
Massimo Loda ◽  
Gasan Mackarem ◽  
Silvano Bosari ◽  
Ronald A. DeLellis ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Invasive Breast Carcinoma ◽  
Node Negative

scholarly journals ADAMTS8 Expression is a Potential Prognostic Biomarker for Postoperative Metastasis in Lymph Node-Negative Early-Stage Invasive Breast Carcinoma Patients

2021 ◽  
Vol Volume 14 ◽  
pp. 1701-1713
Author(s):  
Yao Li ◽  
Xin Yang ◽  
Jie Sun ◽  
Yangyang Zhao ◽  
Qi Zhou ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Prognostic Biomarker ◽  
Early Stage ◽  
Invasive Breast Carcinoma ◽  
Node Negative

Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma

2004 ◽  
Vol 88 (1) ◽  
pp. 75-85 ◽  
Author(s):  
He-cheng Li ◽  
Dao-cheng Cao ◽  
Yi Liu ◽  
Yi-feng Hou ◽  
Jiong Wu ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Matrix Metalloproteinases ◽  
Prognostic Value ◽  
Node Negative

scholarly journals Prognostic value of DNA cytometry in 281 premenopausal patients with lymph node negative breast carcinoma randomized in a control trial

Cancer ◽  
2000 ◽  
Vol 89 (8) ◽  
pp. 1748-1757 ◽  
Author(s):  
Anne Marie Mandard ◽  
Yves Denoux ◽  
Paulette Herlin ◽  
Fran�oise Duigou ◽  
Marc J. van de Vijver ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Prognostic Value ◽  
Dna Cytometry ◽  
Node Negative ◽  
Premenopausal Patients

scholarly journals DCBLD1 is associated with the integrin signaling pathway and has prognostic value in non-small cell lung and invasive breast carcinoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Guillaume B. Cardin ◽  
Monique Bernard ◽  
Francis Rodier ◽  
Apostolos Christopoulos
Keyword(s):  
Breast Carcinoma ◽  
Signaling Pathway ◽  
Prognostic Value ◽  
Colorectal Adenocarcinoma ◽  
Prostate Adenocarcinoma ◽  
Small Cell ◽  
Invasive Breast Carcinoma ◽  
Integrin Signaling ◽  
Small Cell Lung ◽  
And Function

AbstractGermline single nucleotide polymorphisms in the promoter region of the DCBLD1 gene are associated with non-smoking cases of both non-small cell lung carcinoma (NSCLC) and human papillomavirus-negative head and neck cancer. However the clinical relevance and function of DCBLD1 remain unclear. This multicenter retrospective study was designed to evaluate the prognostic value and function of DCBLD1 in the four main solid cancers: NSCLC, invasive breast carcinoma, colorectal adenocarcinoma and prostate adenocarcinoma. We included the following cohorts: GSE81089 NSCLC, METABRIC invasive breast carcinoma, GSE14333 colorectal adenocarcinoma, GSE70770 prostate adenocarcinoma and The Cancer Genome Atlas (TCGA) Firehose Legacy cohorts of all four cancers. DCBLD1 gene expression was associated with a worse overall survival in multivariate analyses for both NSCLC cohorts (TCGA: P = 0.03 and GSE81089: P = 0.04) and both invasive breast carcinoma cohorts (TCGA: P = 0.02 and METABRIC: P < 0.001). Patients with high DCBLD1 expression showed an upregulation of the integrin signaling pathway in comparison to those with low DCBLD1 expression in the TCGA NSCLC cohort (FDR = 5.16 × 10–14) and TCGA invasive breast carcinoma cohort (FDR = 1.94 × 10–05).

scholarly journals Prognostic Value of Gene Signatures and Proliferation in Lymph-Node-Negative Breast Cancer

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e90642 ◽  
Author(s):  
Kristin Jonsdottir ◽  
Jörg Assmus ◽  
Aida Slewa ◽  
Einar Gudlaugsson ◽  
Ivar Skaland ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Prognostic Value ◽  
Node Negative ◽  
Gene Signatures ◽  
Node Negative Breast Cancer

scholarly journals The Prognostic Value of Lymph Nodes Dissection Number on Survival of Patients with Lymph Node-Negative Gastric Cancer

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Wu Song ◽  
Yujie Yuan ◽  
Liang Wang ◽  
Weiling He ◽  
Xinhua Zhang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Overall Survival ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Tumor Invasion ◽  
Prognostic Value ◽  
Operation Time ◽  
Invasion Depth ◽  
Node Negative ◽  
Tumor Invasion Depth

Objective.The study was designed to explore the prognostic value of examined lymph node (LN) number on survival of gastric cancer patients without LN metastasis.Methods.Between August 1995 and January 2011, 300 patients who underwent gastrectomy with D2 lymphadenectomy for LN-negative gastric cancer were reviewed. Patients were assigned to various groups according to LN dissection number or tumor invasion depth. Some clinical outcomes, such as overall survival, operation time, length of stay, and postoperative complications, were compared among all groups.Results.The overall survival time of LN-negative GC patients was50.2±30.5months. Multivariate analysis indicated that LN dissection number(P<0.001)and tumor invasion depth(P<0.001)were independent prognostic factors of survival. The number of examined LNs was positively correlated with survival time(P<0.05)in patients with same tumor invasion depth but not correlated with T1 stage or examined LNs>30. Besides, it was not correlated with operation time, transfusion volume, length of postoperative stay, or postoperative complication incidence(P>0.05).Conclusions.The number of examined lymph nodes is an independent prognostic factor of survival for patients with lymph node-negative gastric cancer. Sufficient dissection of lymph nodes is recommended during surgery for such population.

Sign in / Sign up

Export Citation Format

Share Document