Synthesis and characterization of new types of halogenated and alkylated imidazolidineiminothiones and a comparative study of their antitumor, antibacterial, and antifungal activities

2011 ◽  
Vol 46 (6) ◽  
pp. 2280-2289 ◽  
Author(s):  
Ziad Moussa ◽  
Marwa A.M.Sh. El-Sharief ◽  
Ahmed M.Sh. El-Sharief
2021 ◽  
pp. 3307-3322
Author(s):  
Muath Jabbar Tarfa Al-Abbasee ◽  
Ahmood khalaf Jebur ◽  
Afraa Sabir Shihab

    Some new tropylidene derivatives were prepared in this work and their in vitro antibacterial and antifungal activities were studied. All the prepared compounds were characterized by their physical properties, such as melting point and color, and chemical properties, using the techniques of FT-IR, 1H-NMR and 13C-NMR.


2011 ◽  
Vol 11 (2) ◽  
pp. 148-153
Author(s):  
Hemant Panwar ◽  
Shishupal Singh

3-Aryl-5H,13aH-quinolino(3,2-f)(1,2,4)triazolo(4,3-b)(1,2-diaza-4-sulpho)azepines [2a-i] have been prepared by the cyclisation of 5-aryl-4-amino-3-mercapto-1,2,4-triazole by reaction with 2-chloro-3-formylquinoline in catalytic presence of p-toluene sulphonic acid. All the synthesized compounds have been characterized by elemental and spectral (IR, 1H- NMR and Mass) analysis. Furthermore, all compounds were evaluated for their antibacterial and antifungal activities against selected panel of pathogenic strains. Ampicillin trihydrate and fluconazole were used as standard drugs for antibacterial and antifungal activity, respectively. 3-(2-Chloro)phenyl-5H,13aH-quinolino(3,2-f)(1,2,4)triazolo(4,3-b)(1,2-diaza-4-sulpho)azepine [2h] was found, one of the most potent with lesser toxicity among the all prepared thiazepine derivatives.


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