Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship

Carbonic Anhydrase Ix ◽

Activity Relationship ◽

Quantitative structure–activity relationship (QSAR) studies on a series of 1,3,4-thiadiazole-2-thione derivatives as tumor-associated carbonic anhydrase IX inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756360802361514 ◽

2008 ◽

Vol 24 (3) ◽

pp. 722-729 ◽

Cited By ~ 5

Author(s):

Mohammed K. Abdel-Hamid ◽

Atef A. Abdel-Hafez ◽

Nawal A. El-Koussi ◽

Nadia M. Mahfouz

Keyword(s):

Carbonic Anhydrase ◽

Carbonic Anhydrase Ix ◽

Activity Relationship ◽

Quantitative Structure ◽

Qsar Studies ◽

Convergent synthesis of carbonic anhydrase inhibiting bi‐heterocyclic benzamides: Structure–activity relationship and mechanistic explorations through enzyme inhibition, kinetics, and computational studies

Journal of Heterocyclic Chemistry ◽

10.1002/jhet.4240 ◽

2021 ◽

Author(s):

Farhan M. Khan ◽

Muhammad A. Abbasi ◽

Aziz‐ur‐Rehman ◽

Sabahat Z. Siddiqui ◽

Abdul R. Sadiq Butt ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Enzyme Inhibition ◽

Activity Relationship ◽

Computational Studies ◽

Inhibition Kinetics ◽

Convergent Synthesis ◽

Structure Activity ◽

Enzyme Inhibition Kinetics

Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2020.1722121 ◽

2020 ◽

Vol 35 (1) ◽

pp. 598-609 ◽

Cited By ~ 4

Author(s):

Adel S. El-Azab ◽

Alaa A.-M. Abdel-Aziz ◽

Hany E. A. Ahmed ◽

Sivia Bua ◽

Alessio Nocentini ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Activity Relationship ◽

Structure Activity ◽

Human Carbonic Anhydrase ◽

Relationship Of

Development of Quantitative Structure−Activity Relationship and Classification Models for a Set of Carbonic Anhydrase Inhibitors

Journal of Chemical Information and Computer Sciences ◽

10.1021/ci0100696 ◽

2001 ◽

Vol 42 (1) ◽

pp. 94-102 ◽

Cited By ~ 27

Author(s):

Brian E. Mattioni ◽

Peter C. Jurs

Keyword(s):

Carbonic Anhydrase ◽

Activity Relationship ◽

Classification Models ◽

Quantitative Structure ◽

Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.111638 ◽

2019 ◽

Vol 182 ◽

pp. 111638 ◽

Cited By ~ 11

Author(s):

Davide Moi ◽

Alessio Nocentini ◽

Alessandro Deplano ◽

Gianfranco Balboni ◽

Claudiu T. Supuran ◽

...

Keyword(s):

Carbonic Anhydrase ◽

Synthesis And Biological Evaluation

Biological Evaluation ◽

Activity Relationship ◽

Structure Activity ◽

Diarylsulfonamides and their bioisosteres as dual inhibitors of alkaline phosphatase and carbonic anhydrase: Structure activity relationship and molecular modelling studies

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2015.03.054 ◽

2015 ◽

Vol 23 (10) ◽

pp. 2435-2444 ◽

Cited By ~ 26

Author(s):

Mariya al-Rashida ◽

Syeda Abida Ejaz ◽

Sharafat Ali ◽

Aisha Shaukat ◽

Mehwish Hamayoun ◽

...

Keyword(s):

Alkaline Phosphatase ◽

Carbonic Anhydrase ◽

Molecular Modelling ◽

Activity Relationship ◽

Structure Activity ◽

Molecular Modelling Studies ◽

Modelling Studies ◽

Dual Inhibitors

A quantitative structure–activity relationship study on some aromatic/heterocyclic sulfonamides and their charged derivatives acting as carbonic anhydrase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756360500067439 ◽

2005 ◽

Vol 20 (3) ◽

pp. 251-259 ◽

Cited By ~ 5

Author(s):

S. P. Gupta ◽

S. Kumaran

Keyword(s):

Carbonic Anhydrase ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Study ◽

Aromatic Heterocyclic

Carbonic anhydrase inhibitors. Part 24. A quantitative structure-activity relationship study of positively charged sulfonamide inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/0223-5234(96)88286-9 ◽

1995 ◽

Vol 30 (9) ◽

pp. 687-696 ◽

Cited By ~ 47

Author(s):

CT Supuran ◽

BW Clare

Keyword(s):

Carbonic Anhydrase ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Study ◽

Positively Charged

ChemInform Abstract: Development of Quantitative Structure-Activity Relationship and Classification Models for a Set of Carbonic Anhydrase Inhibitors.

ChemInform ◽

10.1002/chin.200221211 ◽

2010 ◽

Vol 33 (21) ◽

pp. no-no

Author(s):

Brian E. Mattioni ◽

Peter C. Jurs

Keyword(s):

Carbonic Anhydrase ◽

Activity Relationship ◽

Classification Models ◽

Quantitative Structure ◽

Structure–activity relationship of human carbonic anhydrase C and sulfonamide drugs: a molecular mechanics approach

Acta Crystallographica Section A Foundations of Crystallography ◽

10.1107/s0108767384087055 ◽

1984 ◽

Vol 40 (a1) ◽

pp. C439-C439

Author(s):

E. F. Meyer Jr ◽

A. Vedani

Keyword(s):

Carbonic Anhydrase ◽

Molecular Mechanics ◽

Activity Relationship ◽

Structure Activity ◽

Human Carbonic Anhydrase ◽

Relationship Of