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2014 ◽  
Vol 87 ◽  
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Author(s):  
Goran Benedeković ◽  
Mirjana Popsavin ◽  
Jovana Francuz ◽  
Ivana Kovačević ◽  
Vesna Kojić ◽  
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Sar Analysis ◽  
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Triazine-Based Vanilloid 1 Receptor Open Channel Blockers: Design, Synthesis, Evaluation, and SAR Analysis

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Miquel Vidal-Mosquera ◽  
Asia Fernández-Carvajal ◽  
Alejandra Moure ◽  
Pierluigi Valente ◽  
Rosa Planells-Cases ◽  
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Open Channel ◽  
Channel Blockers ◽  
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Design, synthesis, and SAR analysis of cytotoxic sinapyl alcohol derivatives

2006 ◽  
Vol 14 (6) ◽  
pp. 2060-2071 ◽  
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Hong Bin Zou ◽  
Sheng Yi Dong ◽  
Chang Xin Zhou ◽  
Li Hong Hu ◽  
Yi Hang Wu ◽  
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Design Synthesis ◽  
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Design, synthesis, and SAR analysis of novel selective σ1 ligands

2007 ◽  
Vol 15 (2) ◽  
pp. 771-783 ◽  
Author(s):  
Simona Collina ◽  
Guya Loddo ◽  
Mariangela Urbano ◽  
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ChemInform Abstract: Design, Synthesis and Antiproliferative Activity of Styryl Lactones Related to (+)-Goniofufurone.

ChemInform ◽  
2010 ◽  
Vol 41 (42) ◽  
Author(s):  
Velimir Popsavin ◽  
Bojana Sreco ◽  
Goran Benedekovic ◽  
Jovana Francuz ◽  
Mirjana Popsavin ◽  
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Design, synthesis and SAR analysis of novel selective σ1 ligands (Part 2)

2010 ◽  
Vol 18 (3) ◽  
pp. 1204-1212 ◽  
Author(s):  
Daniela Rossi ◽  
Mariangela Urbano ◽  
Alice Pedrali ◽  
Massimo Serra ◽  
Daniele Zampieri ◽  
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Design Synthesis ◽  
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Design, synthesis and SAR analysis of potent BACE1 inhibitors: Possible lead drug candidates for Alzheimer's disease

2017 ◽  
Vol 125 ◽  
pp. 1213-1224 ◽  
Author(s):  
Hamadeh Tarazi ◽  
Raed Abu Odeh ◽  
Raed Al-Qawasmeh ◽  
Imad Abu Yousef ◽  
Wolfgang Voelter ◽  
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Alzheimer’S Disease ◽  
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Drug Candidates ◽  
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Discovery of imidazopyridines containing isoindoline-1,3-dione framework as a new class of BACE1 inhibitors: Design, synthesis and SAR analysis

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Sara Azimi ◽  
Afsaneh Zonouzi ◽  
Omidreza Firuzi ◽  
Aida Iraji ◽  
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Design Synthesis ◽  
New Class ◽  
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Discovery of novel quinazolinones and their acyclic analogues as multi-kinase inhibitors: design, synthesis, SAR analysis and biological evaluation

RSC Advances ◽  
2016 ◽  
Vol 6 (113) ◽  
pp. 111767-111786 ◽  
Author(s):  
Nehad A. El Sayed ◽  
Amal A. Eissa ◽  
Ghada F. El Masry ◽  
Mohamed M. Abdullah ◽  
Reem K. Arafa
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Biological Evaluation ◽  
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Sar Analysis ◽  
Mcf 7

MCF-7 IC50 = 0.000012 μM; MDA-MB-231 IC50 = 0.00010 μM; HS-578T IC50 = 0.00045 μM, ABL IC50 = 0.011 nM.

Head-to-head bisbenzazole derivatives as antiproliferative agents: design, synthesis, in vitro activity, and SAR analysis

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Tugba Ertan-Bolelli ◽  
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Design Synthesis ◽  
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