Advances in tetrahydropyrido[1,2- a ]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors

Cyclin Dependent Kinase ◽

Differential Cellular Phosphorylation of Neurofilament Heavy Side-Arms by Glycogen Synthase Kinase-3 and Cyclin-Dependent Kinase-5

Journal of Neurochemistry ◽

10.1046/j.1471-4159.1996.66041698.x ◽

2002 ◽

Vol 66 (4) ◽

pp. 1698-1706 ◽

Cited By ~ 82

Author(s):

Sonia Guidato ◽

Li-Huei Tsai ◽

Jim Woodgett ◽

Christopher C. J. Miller

Keyword(s):

Glycogen Synthase ◽

Cyclin Dependent Kinase ◽

The Roles of Cyclin-dependent Kinase 5 and Glycogen Synthase Kinase 3 in Tau Hyperphosphorylation

Journal of Biological Chemistry ◽

10.1074/jbc.m603469200 ◽

2006 ◽

Vol 281 (35) ◽

pp. 25457-25465 ◽

Cited By ~ 229

Author(s):

Florian Plattner ◽

Marco Angelo ◽

K. Peter Giese

Keyword(s):

Glycogen Synthase ◽

Tau Hyperphosphorylation ◽

Cyclin Dependent Kinase ◽

Faculty Opinions recommendation of Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1105273.561481 ◽

2008 ◽

Author(s):

Riqiang Yan

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Tau Phosphorylation ◽

Protein Processing ◽

Precursor Protein ◽

Amyloid Precursor Protein Processing ◽

Cyclin Dependent Kinase ◽

Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways

Brain Research Bulletin ◽

10.1016/j.brainresbull.2011.03.006 ◽

2011 ◽

Vol 85 (3-4) ◽

pp. 194-200 ◽

Cited By ~ 26

Author(s):

Jiang-Ping Hu ◽

Jing-Wei Xie ◽

Chun-Yan Wang ◽

Tao Wang ◽

Xu Wang ◽

...

Keyword(s):

Signaling Pathways ◽

Glycogen Synthase ◽

Tau Phosphorylation ◽

Cyclin Dependent Kinase ◽

Regulation of phosphorylation of tau by cyclin-dependent kinase 5 and glycogen synthase kinase-3 at substrate level

FEBS Letters ◽

10.1016/j.febslet.2006.09.060 ◽

2006 ◽

Vol 580 (25) ◽

pp. 5925-5933 ◽

Cited By ~ 41

Author(s):

Amitabha Sengupta ◽

Michal Novak ◽

Inge Grundke-Iqbal ◽

Khalid Iqbal

Keyword(s):

Glycogen Synthase ◽

Cyclin Dependent Kinase ◽

Substrate Level ◽

Testosterone prevents the heat shock-induced overactivation of glycogen synthase kinase-3 but not of cyclin-dependent kinase 5 and c-Jun NH2-terminal kinase and concomitantly abolishes hyperphosphorylation of : Implications for Alzheimer's disease

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.032646799 ◽

2002 ◽

Vol 99 (3) ◽

pp. 1140-1145 ◽

Cited By ~ 52

Author(s):

S. C. Papasozomenos ◽

A. Shanavas

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Heat Shock ◽

Glycogen Synthase ◽

Cyclin Dependent Kinase ◽

Interplay between Cyclin-Dependent Kinase 5 and Glycogen Synthase Kinase 3 Mediated by Neuregulin Signaling Leads to Differential Effects on Tau Phosphorylation and Amyloid Precursor Protein Processing

Journal of Neuroscience ◽

10.1523/jneurosci.5245-07.2008 ◽

2008 ◽

Vol 28 (10) ◽

pp. 2624-2632 ◽

Cited By ~ 91

Author(s):

Y. Wen ◽

E. Planel ◽

M. Herman ◽

H. Y. Figueroa ◽

L. Wang ◽

...

Keyword(s):

Amyloid Precursor Protein ◽

Glycogen Synthase ◽

Tau Phosphorylation ◽

Protein Processing ◽

Precursor Protein ◽

Amyloid Precursor Protein Processing ◽

Cyclin Dependent Kinase ◽

Phosphorylation of Neurofilament Heavy-Chain Side-Arm Fragments by Cyclin-Dependent Kinase-5 and Glycogen Synthase Kinase-3α in Transfected Cells

Journal of Neurochemistry ◽

10.1046/j.1471-4159.1997.69020737.x ◽

2002 ◽

Vol 69 (2) ◽

pp. 737-743 ◽

Cited By ~ 29

Author(s):

Narinder P. S. Bajaj ◽

Christopher C. J. Miller

Keyword(s):

Heavy Chain ◽

Glycogen Synthase ◽

Cyclin Dependent Kinase ◽

Transfected Cells ◽

Hippocampal Glycogen Synthase Kinase 3β is Critical for the Antidepressant Effect of Cyclin-Dependent Kinase 5 Inhibitor in Rats

Journal of Molecular Neuroscience ◽

10.1007/s12031-014-0254-2 ◽

2014 ◽

Vol 54 (1) ◽

pp. 92-99 ◽

Cited By ~ 10

Author(s):

Gang Li ◽

Ting Liu ◽

Xiangqian Kong ◽

Lei Wang ◽

Xing Jin

Keyword(s):

Glycogen Synthase ◽

Antidepressant Effect ◽

Cyclin Dependent Kinase ◽

Glycogen Synthase Kinase 3Β ◽

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3β and cyclin-dependent kinase 5, a component of TPK II

Acta Neuropathologica ◽

10.1007/s004010050513 ◽

1996 ◽

Vol 92 (3) ◽

pp. 232-241 ◽

Cited By ~ 168

Author(s):

Haruyasu Yamaguchi ◽

Koichi Ishiguro ◽

Tsuneko Uchida ◽

Akihiko Takashima ◽

Cynthia A. Lemere ◽

...

Keyword(s):

Protein Kinase ◽

Neurofibrillary Tangles ◽

Tau Protein ◽

Glycogen Synthase ◽

Cyclin Dependent Kinase ◽

Glycogen Synthase Kinase 3Β ◽

Tau Protein Kinase ◽

Cyclin Dependent Kinase 5 ◽

Alzheimer Neurofibrillary Tangles