scholarly journals Design, synthesis and biological evaluation of hybrid nitroxide-based non-steroidal anti-inflammatory drugs

2018 ◽  
Vol 147 ◽  
pp. 34-47 ◽  
Author(s):  
Komba Thomas ◽  
Terry W. Moody ◽  
Robert T. Jensen ◽  
Jason Tong ◽  
Cassie L. Rayner ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation

scholarly journals Design, Synthesis and Biological Evaluation of Novel 1, 3, 4-Oxadiazole Bearing Pyridine Moiety

2019 ◽  
pp. 300-307
Author(s):  
Asma D. Ambekari ◽  
Shrinivas K. Mohite
Keyword(s):  
Antimicrobial Activity ◽  
Mass Spectra ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Pyridine Moiety ◽  
Anti Inflammatory ◽  
Physicochemical Data ◽  
Synthesis And Biological Evaluation

Series of novel substituted Synthesis of N-{[5-(substituted)-1,3,4-oxadiazole-2-yl] carbamothioyl} derivatives containing 1,3,4-oxadiazole moiety were synthesized by microwave as a green chemistry method and conventional method by using pyridine 3- carboxylic acid as a starting material. The structures of the synthesized compounds were characterized by physicochemical data, IR, Mass spectra and 1HNMR. All the newly synthesized compound screened for their antimicrobial and In-vivo and In-vitro Anti-inflammatory studies. Anti-inflammatory studies revealed that compound 4f showed significant in-vivo and in-vitro anti-inflammatory activity as well potent antimicrobial activity.

Design, synthesis and biological evaluation of alantolactone derivatives as potential anti-inflammatory agents

2019 ◽  
Vol 28 (6) ◽  
pp. 849-856 ◽  
Author(s):  
Chetan Kumar ◽  
Anil Kumar ◽  
Yedukondalu Nalli ◽  
Waseem I. Lone ◽  
Naresh K. Satti ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation

Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities

2020 ◽  
Vol 94 ◽  
pp. 103371 ◽  
Author(s):  
Khalid M. Attalah ◽  
Ashraf N. Abdalla ◽  
Akhmed Aslam ◽  
Muhammad Ahmed ◽  
Mohammed A.S. Abourehab ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ethyl Benzoate ◽  
Cytotoxic Activities ◽  
Design Synthesis ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation

Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents

2014 ◽  
Vol 62 ◽  
pp. 197-211 ◽  
Author(s):  
Ahmed H. Abdelazeem ◽  
Shaimaa A. Abdelatef ◽  
Mohammed T. El-Saadi ◽  
Hany A. Omar ◽  
Shabana I. Khan ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Anti Inflammatory ◽  
Synthesis And Biological Evaluation
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