Design, Synthesis and Biological Evaluation of Novel 1, 3, 4-Oxadiazole Bearing Pyridine Moiety
2019 ◽
pp. 300-307
Keyword(s):
Series of novel substituted Synthesis of N-{[5-(substituted)-1,3,4-oxadiazole-2-yl] carbamothioyl} derivatives containing 1,3,4-oxadiazole moiety were synthesized by microwave as a green chemistry method and conventional method by using pyridine 3- carboxylic acid as a starting material. The structures of the synthesized compounds were characterized by physicochemical data, IR, Mass spectra and 1HNMR. All the newly synthesized compound screened for their antimicrobial and In-vivo and In-vitro Anti-inflammatory studies. Anti-inflammatory studies revealed that compound 4f showed significant in-vivo and in-vitro anti-inflammatory activity as well potent antimicrobial activity.
2019 ◽
Vol 15
(5)
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pp. 521-536
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Keyword(s):
2022 ◽
Vol 227
◽
pp. 113888
2019 ◽
Vol 182
◽
pp. 111670
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2012 ◽
Vol 22
(21)
◽
pp. 6705-6711
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Keyword(s):