Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation

2021 ◽  
Vol 216 ◽  
pp. 113265
Author(s):  
Wei Yan ◽  
Lingtian Zhang ◽  
Fengping Lv ◽  
Marialuisa Moccia ◽  
Francesca Carlomagno ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Type Ii ◽  
Receptor Kinase ◽  
Design Synthesis ◽  
Trk Inhibitors ◽  
Synthesis And Biological Evaluation

Design, synthesis and biological evaluation of type-II VEGFR-2 inhibitors based on quinoxaline scaffold

2014 ◽  
Vol 56 ◽  
pp. 16-26 ◽  
Author(s):  
Mai I. Shahin ◽  
Dalal A. Abou El Ella ◽  
Nasser S.M. Ismail ◽  
Khaled A.M. Abouzid
Keyword(s):  
Biological Evaluation ◽  
Type Ii ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

scholarly journals Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors

2016 ◽  
Vol 59 (8) ◽  
pp. 3793-3807 ◽  
Author(s):  
Helen V. Waldschmidt ◽  
Kristoff T. Homan ◽  
Osvaldo Cruz-Rodríguez ◽  
Marilyn C. Cato ◽  
Jessica Waninger-Saroni ◽  
...  
Keyword(s):  
G Protein ◽  
Biological Evaluation ◽  
Receptor Kinase ◽  
G Protein Coupled Receptor ◽  
Design Synthesis ◽  
G Protein Coupled ◽  
Synthesis And Biological Evaluation

scholarly journals Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Jaideep B. Bharate ◽  
Nicholas McConnell ◽  
Gunaganti Naresh ◽  
Lingtian Zhang ◽  
Naga Rajiv Lakkaniga ◽  
...  
Keyword(s):  
Rational Design ◽  
Biological Evaluation ◽  
Type Ii ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation
Sign in / Sign up

Export Citation Format

Share Document