Balancing Potency and Basicity by Incorporating Fluoropyridine Moieties: Discovery of a 1-Amino-3,4-dihydro-2,6-naphthyridine BACE1 Inhibitor That Affords Robust and Sustained Central Aβ Reduction
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2005 ◽
Vol 13
(23)
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pp. 6551-6555
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2010 ◽
Vol 114
(2)
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pp. 374-385
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2012 ◽
Vol 287
(49)
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pp. 41245-41257
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