Design, synthesis, and biological evaluation of nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation

2021 ◽  
Vol 217 ◽  
pp. 113359
Author(s):  
Shuai-Jiang Liu ◽  
Qian Zhao ◽  
Cheng Peng ◽  
Qing Mao ◽  
Fengbo Wu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Glutathione Peroxidase ◽  
Biological Evaluation ◽  
Breast Adenocarcinoma ◽  
Design Synthesis ◽  
Adenocarcinoma Cell ◽  
Mouse Double Minute ◽  
Double Minute ◽  
Dual Inhibitors ◽  
Synthesis And Biological Evaluation

scholarly journals Design, Synthesis and Biological Evaluation of Novel Phenylsulfonylurea Derivatives as PI3K/mTOR Dual Inhibitors

Molecules ◽  
2018 ◽  
Vol 23 (7) ◽  
pp. 1553
Author(s):  
Bingbing Zhao ◽  
Fei Lei ◽  
Caolin Wang ◽  
Binliang Zhang ◽  
Zunhua Yang ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Dual Inhibitors ◽  
Synthesis And Biological Evaluation

scholarly journals Correction: Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation

RSC Advances ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 4927-4927
Author(s):  
Vegard Torp Lien ◽  
Margrethe Konstanse Kristiansen ◽  
Solveig Pettersen ◽  
Mads Haugland Haugen ◽  
Stefan Krauss ◽  
...  
Keyword(s):  
Wnt Signaling ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Dual Inhibitors ◽  
Synthesis And Biological Evaluation

Correction for ‘Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation’ by Vegard Torp Lien et al., RSC Adv., 2019, 9, 37092–37100.

Design, synthesis and biological evaluation of 2-amino-N-(2-aminophenyl)thiazole-5-carboxamide derivatives as novel Bcr-Abl and histone deacetylase dual inhibitors

RSC Advances ◽  
2016 ◽  
Vol 6 (105) ◽  
pp. 103178-103184 ◽  
Author(s):  
Xin Chen ◽  
Shuang Zhao ◽  
Yichao Wu ◽  
Yadong Chen ◽  
Tao Lu ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Inhibitory Activity ◽  
Biological Evaluation ◽  
Design Approach ◽  
Design Synthesis ◽  
Dual Inhibitors ◽  
Synthesis And Biological Evaluation ◽  
Novel Design

A novel design approach: combination of Bcr-Abl and HDAC inhibitory activity in one molecule to produce dual inhibitors.

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