Do threshold values of ovarian volume and follicle number for diagnosing polycystic ovarian syndrome in Turkish women differ from western countries?

ABSTRACT Background Patients with polycystic ovarian syndrome (PCOS) are believed to have large ovaries due to increased stroma. They also have derangement in luteinizing hormone (LH) and testosterone levels and high insulin resistance. As insulin resistance is thought to be associated with androgen and stromal excess, correlation was expected between insulin resistance and stromal excess. Aim To assess if ovarian and stromal volumes in PCOS patients have any correlation with fasting and postprandial insulin levels. Materials and methods A prospective study of 153 subfertile patients was done over a period 18 months. After detailed history, clinical examination and informed consent of all patients were scanned by two-dimensional (2D) on day 3 of the cycle. Patients were divided into PCOS and non-PCOS groups according to Rotterdam criteria. Patients with hormonal derangements other than PCOS were excluded from the study. Patients were assessed by three-dimensional (3D) ultrasound (US) for ovarian and stromal volumes and fasting and postprandial insulin levels were checked on the same day. Results With Pearson correlation significance level of 0.354 (2 tailed) correlation for ovarian volume to fasting insulin was 0.588, for ovarian volume to postprandial insulin was 0.523, for stromal volume to fasting insulin was 0.601, and for stromal volume to postprandial insulin was 0.523. No correlation could be established in non-PCOS group. Conclusion In PCOS patients, a strong correlation was found between ovarian and stromal volume and fasting and post prandial insulin levels. How to cite this article Panchal S, Nagori CB. Correlation of Ovarian and Stromal Volumes to Fasting and Postprandial Insulin Levels in Polycystic Ovarian Syndrome Patients. Int J Infertil Fetal Med 2014;5(1):12-14.

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Is there relationship between serum Igf-1 and thyroid nodule, thyroid or ovarian volume in polycystic ovarian syndrome?

Endocrine Abstracts ◽

10.1530/endoabs.70.ep377 ◽

2020 ◽

Author(s):

Ömercan Topaloğlu ◽

Bahri Evren ◽

Mehmet Uzun ◽

Saim Yoloğlu ◽

Emek Güldoğan ◽

...

Keyword(s):

Thyroid Nodule ◽

Polycystic Ovarian Syndrome ◽

Ovarian Volume ◽

Ovarian Syndrome

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GnRH-agonist therapy in women with the polycystic ovarian syndrome: Effects on ovarian volume and on gonadotropin and sex steroid levels

Gynecological Endocrinology ◽

10.3109/09513598909152470 ◽

1989 ◽

Vol 3 (4) ◽

pp. 309-315 ◽

Cited By ~ 1

Author(s):

P. O. Dale ◽

T. Tanbo ◽

E. Haug ◽

T. Arbyholm

Keyword(s):

Gnrh Agonist ◽

Polycystic Ovarian Syndrome ◽

Sex Steroid ◽

Agonist Therapy ◽

Ovarian Volume ◽

Ovarian Syndrome

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Clinical, ultrasonographical and hormonal correlation in women with polycystic ovarian syndrome

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20184980 ◽

2018 ◽

Vol 7 (12) ◽

pp. 5134

Author(s):

Ashwini Sidhmalswamy G. ◽

Jyoti S. Ghongdemath ◽

Sreedhar Venkatesh

Keyword(s):

Testosterone Level ◽

Polycystic Ovarian Syndrome ◽

Free Testosterone ◽

Cross Sectional Study ◽

Obese Women ◽

Cross Sectional ◽

Ovarian Volume ◽

The Mean ◽

Free Testosterone Level ◽

Ovarian Syndrome

Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women of fertile age. The prevalence, time of onset and severity of clinical presentation vary among different ethnic and racial groups. Though there is significant reproductive, endocrine and metabolic morbidity of PCOS, very little is known about its different modes of presentation in Indian population. A cross sectional observational study. The objective To study the correlation between the clinical, ultrasonographical and hormonal features in women diagnosed as PCOS based on the revised diagnostic criteria, 2003.Methods: A cross-sectional study of 74 PCOS women who had oligo ovulatory cycles and polycystic ovarian morphology on ultrasound was done. Data about menstrual history and anthropometric measurements were collected. Clinical observations of acne and hirsutism were made. Transvaginal ultrasonography and biochemical analysis for free testosterone was done.Results: In all, 74 PCOS women were studied and analyzed. The mean age was 24.884.03, mean BMI was 25.48 ±3.75 and mean free testosterone was 3.81±4.05. Among the PCOS women 39.8% were hirsute, 10.1% were obese, 2.3% had acne and 38% were hyperandrogenemic. Of the hyperandrogenemic women 61.2% were hirsute, 53.22% were obese and 36.54% had acne. The association between BMI and free testosterone level was statistically significant (p=0.0023). BMI was moderately correlated with hyperandrogenemia (r=0.446). The mean left ovarian volume was higher in obese than in non-obese women, which was statistically significant (p=0.003). The mean left ovarian volume was high in hyperandrogenemic women which was statistically significant (p=0.00034).Conclusions: In the present study it was found that there is association between obesity and free testosterone level which was significant. There was statistically significant association between ovarian volume and obesity. Similarly, there was association between ovarian volume and hyperandrogenemia which was significant. Hirsutism and acne had no association with hyperandrogenemia.

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Differentiation Between Phenotypes of Polycystic Ovarian Syndrome With Sonography

Journal of Diagnostic Medical Sonography ◽

10.1177/8756479321996676 ◽

2021 ◽

pp. 875647932199667

Author(s):

Ahmed Abdel Khalek Abdel Razek ◽

Heba Abou Elatta

Keyword(s):

Polycystic Ovarian Syndrome ◽

Plate Thickness ◽

Area Under The Curve ◽

Serum Testosterone ◽

The Body ◽

Serum Testosterone Level ◽

Transvaginal Sonography ◽

Ovarian Volume ◽

Follicle Size ◽

Ovarian Syndrome

Objectives: To differentiate between the classic (A/B) from the nonclassic (C/D) phenotypes of the polycystic ovarian syndrome (PCOS) with sonography. Materials & Methods: Retrospective analysis was performed upon 72 female patients with PCOS. All patients underwent transvaginal sonography. The patients were classified into classic and nonclassic phenotypes of PCOS. Image analysis was performed for the ovarian volume, follicle counts, follicle size, and endometrial plate thickness. Results: There were significant differences in the ovarian volume ( P = .001), follicle counts ( P = .001), follicle size ( P = .001), and endometrial plate thickness ( P = .001) between classic and nonclassic phenotypes of PCOS. The threshold value for ovarian volume, follicle count, follicle size, and endometrial plate thickness used to differentiate classic from nonclassic phenotypes were 12.5, 10.5, 5.25, and 5.75, respectively, with an area under the curve of 0.79, 0.82, 0.83, 0.77 and an accuracy of 75%, 73.6%, 79.2%, and 68.1%, respectively. The serum testosterone level and the body mass index were significantly higher in patients with classic than nonclassic phenotypes of PCOS ( P = .001, .04), respectively. Conclusion: Sonography findings can differentiate classic from nonclassic phenotypes of PCOS.

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