Local anesthetic versus forced coughing at colposcopic-guided biopsy: a prospective study

Abstract Objective To evaluate the accuracy and safety of contrast-enhanced ultrasound (CEUS) guided biopsy in the diagnosis of radiologically determined pleural based lesions. Method A prospective study was conducted on patients with radiologically determined pleural based lesions. Patients who met the inclusion criteria received pleural biopsy guided by CEUS to obtain specimens, followed by histomathological and microbiological examinations. After treatment and follow-up, surgical thoracoscopy was performed on cases with undefinite diagnosis. Result A total of 460 patients were finally included. CEUS showed internal necrosis in 72.17% cases and obvious peripheral vessels in 55.43% cases, both of which were significantly higher than the conventional ultrasound imaged (p < 0.05). The diagnostic accuracy through CEUS guided biopsy sampling was 98.91% (455/460). The microbiological diagnostic yield achieved 71.88% (225/313) in infectious lesions. In 330 cases combined pleural effusion, CEUS guided biopsy increased the diagnostic yield from 60.30% (199 /330) to 98.36% (325 /330) in all cases (p < 0.05), from 15.56% (14/90) to 94.44% (85/90) in malignant lesions (p < 0.01) and from 77.08% (185/240) to 100% (240/240) in infectious lesions (p < 0.05). No serious adverse events occurred. Conclusion CEUS guided biopsy provides a minimally invasive, effective and safe diagnostic biopsy method for pleural lesions. Clinical Trials Registration: Chinese Clinical Trial Registry ChiCTR2000029749 (ChiCTR, www.chictr.org.cn).

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A prospective study on pain score with transperineal prostatic gold seed fiducial implantation under local anesthetic alone

Canadian Urological Association Journal ◽

10.5489/cuaj.11225 ◽

2012 ◽

pp. 1-5

Author(s):

Colin. I. Tang ◽

Perakaa Sethukavalan ◽

Patrick Cheung ◽

Gerard Morton ◽

Geordi Pang ◽

...

Keyword(s):

Prospective Study ◽

Pain Score ◽

Local Anesthetic ◽

Gold Seed ◽

A Prospective Study

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Contrast-Enhanced Ultrasound Guided Pleural Biopsy Improves Diagnostic Confidence in Multidisciplinary Diagnosis of Pleural Lesions: A 3-year Prospective Study

10.21203/rs.3.rs-424800/v1 ◽

2021 ◽

Author(s):

Wenwen Sun ◽

Yiming Zhou ◽

Cong Yang ◽

Zhengwei Dong ◽

ZheMin Zhang ◽

...

Keyword(s):

Prospective Study ◽

Diagnostic Yield ◽

Contrast Enhanced Ultrasound ◽

Clinical Trial Registry ◽

Pleural Biopsy ◽

Serious Adverse Events ◽

Guided Biopsy ◽

Contrast Enhanced ◽

Diagnostic Biopsy ◽

A Prospective Study

Abstract Objective: To evaluate the accuracy and safety of contrast-enhanced ultrasound (CEUS) guided biopsy in the diagnosis of pleural lesions.Method: A prospective study was conducted on patients with undiagnosed pleural lesions. Patients who met the inclusion criteria received pleural biopsy guided by CEUS to obtain specimens, followed by histomathological and etiological examinations. After treatment and follow-up, surgical thoracoscopy was performed for cases of undefinite diagnosis.Result: A total of 460 patients were finally included. CEUS showed internal necrosis in 72.17% cases and peripheral obvious vessels 55.43% cases , both of which were significantly higher than the conventional ultrasound imaged (P 0.00). The diagnostic accuracy through CEUS guided biopsy sampling was 98.91% (455/460). The etiological diagnostic yield achieved 88.82% (278/313) in infectious lesions. In 330 cases combined pleural effusion, CEUS guided biopsy increased the diagnostic yield from 60.30 % (199 /330 ) to 98.36 % (325 /330) in all cases (P 0.00）, from 15.56 % (14/90) to 94.44% (85/90) in malignant lesions ( P 0.00）and from 77.08 %（185/240）to 100%（240/240, P 0.00) in infectious lesions. No serious adverse events occurred. Conclusion: CEUS guided biopsy provides a minimally invasive、 effective and safe diagnostic biopsy method for pleural lesions.Clinical Trials Registration: Chinese Clinical Trial Registry ChiCTR2000029749 ( ChiCTR, www.chictr.org.cn )

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Sub-Tenon Anesthesia

Anesthesiology ◽

10.1097/00000542-200304000-00025 ◽

2003 ◽

Vol 98 (4) ◽

pp. 964-968 ◽

Cited By ~ 83

Author(s):

Philip A. Guise

Keyword(s):

New Zealand ◽

Pilot Study ◽

Prospective Study ◽

Local Anesthetic ◽

Sufficient Data ◽

Patient Acceptability ◽

A Prospective Study ◽

Made In ◽

Auckland Hospital ◽

Sharp Needle

Background An initial pilot study of 300 sub-Tenon local anesthetic blocks (STBs) for intraocular surgery established the effectiveness and patient acceptability of the technique. Following this, a decision was made in 1995 to change from sharp needle techniques to STB for all eye surgeries performed during local anesthesia at Auckland Hospital (Auckland, New Zealand) by reeducation of anesthetists and surgeons. At this point, sufficient data were not available to confirm that STB would avoid the complications associated with the passage of sharp needles into the orbit or would cause a different set of serious complications. Methods A prospective study of the next 6,000 consecutive STBs performed at Auckland Hospital was carried out over a period of 6 yr (from 1995 to 2000). Results Sub-Tenon block is very effective, with a surgeon and patient acceptability rate of 98.8%. Insertion of the sub-Tenon cannula and administration of the anesthetic produces minimal discomfort, being completely painless in 68.8% of cases. There were no serious block-related complications in this series, supporting the safety of the sub-Tenon technique. Conclusion The experience at Auckland Hospital provides further support for the avoidance of passing sharp needles into the orbit.

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