Validity of gradient-echo three-dimensional delayed gadolinium-enhanced magnetic resonance imaging of hip joint cartilage: A histologically controlled study

2013 ◽  
Vol 82 (2) ◽  
pp. e81-e86 ◽  
Author(s):  
Christoph Zilkens ◽  
Falk Miese ◽  
Monika Herten ◽  
Sabine Kurzidem ◽  
Marcus Jäger ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hip Joint ◽  
Three Dimensional ◽  
Controlled Study ◽  
Joint Cartilage ◽  
Resonance Imaging ◽  
Gradient Echo

Three-dimensional delayed gadolinium-enhanced magnetic resonance imaging of hip joint cartilage at 3T: A prospective controlled study

2012 ◽  
Vol 81 (11) ◽  
pp. 3420-3425 ◽  
Author(s):  
Christoph Zilkens ◽  
Falk Miese ◽  
Young-Jo Kim ◽  
Harish Hosalkar ◽  
Gerald Antoch ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hip Joint ◽  
Three Dimensional ◽  
Controlled Study ◽  
Joint Cartilage ◽  
Resonance Imaging ◽  
Prospective Controlled Study

3D double-echo steady-state sequence assessment of hip joint cartilage and labrum at 3 Tesla: comparative analysis of magnetic resonance imaging and intraoperative data

2017 ◽  
Vol 27 (10) ◽  
pp. 4360-4371 ◽  
Author(s):  
Christoph Schleich ◽  
Tobias Hesper ◽  
Harish S. Hosalkar ◽  
Fanni Rettegi ◽  
Christoph Zilkens ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Steady State ◽  
Comparative Analysis ◽  
Magnetic Resonance ◽  
Hip Joint ◽  
3 Tesla ◽  
Joint Cartilage ◽  
Resonance Imaging ◽  
State Sequence

scholarly journals Automatic Cartilage Segmentation for Delayed Gadolinium-Enhanced Magnetic Resonance Imaging of Hip Joint Cartilage: A Feasibility Study

Cartilage ◽  
2018 ◽  
Vol 11 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Tobias Hesper ◽  
Bernd Bittersohl ◽  
Christoph Schleich ◽  
Harish Hosalkar ◽  
Rüdiger Krauspe ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Femoral Head ◽  
Hip Joint ◽  
Rank Correlation ◽  
Joint Cartilage ◽  
Resonance Imaging ◽  
Femoral Head Cartilage ◽  
Processing Software ◽  
Joint Assessment

Objective Automatic segmentation for biochemical cartilage evaluation holds promise for an efficient and reader-independent analysis. This pilot study aims to investigate the feasibility and to compare delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) hip joint assessment with manual segmentation of acetabular and femoral head cartilage and dGEMRIC hip joint assessment using automatic surface and volume processing software at 3 Tesla. Design Three-dimensional (3D) dGEMRIC data sets of 6 patients with hip-related pathology were assessed (1) manually including multiplanar image reformatting and regions of interest (ROI) analysis and (2) automated by using a combined surface and volume processing software. For both techniques, T1Gd values were obtained in acetabular and femoral head cartilage at 7 regions (anterior, anterior-superior, superior-anterior, superior, superior-posterior, posterior-superior, and posterior) in central and peripheral portions. Correlation between both techniques was calculated utilizing Spearman’s rank correlation coefficient. Results A high correlation between both techniques was observed for acetabular (ρ = 0.897; P < 0.001) and femoral head (ρ = 0.894; P < 0.001) cartilage in all analyzed regions of the hip joint (ρ between 0.755 and 0.955; P < 0.001). Conclusions Automatic cartilage segmentation with dGEMRIC assessment for hip joint cartilage evaluation seems feasible providing high to excellent correlation with manually performed ROI analysis. This technique is feasible for an objective, reader-independant and reliable assessment of biochemical cartilage status.

scholarly journals Delayed gadolinium-enhanced magnetic resonance imaging of hip joint cartilage (dGEMRIC): pearls and pitfalls

2011 ◽  
Vol 3 (2) ◽  
pp. 11 ◽  
Author(s):  
Bernd Bittersohl
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hip Joint ◽  
Cartilage Damage ◽  
Mr Arthrography ◽  
Image Resolution ◽  
Current Status ◽  
Joint Cartilage ◽  
Resonance Imaging ◽  
Joint Preservation

With the increasing advances in hip joint preservation surgery, accurate diagnosis and assessment of femoral head and acetabular cartilage status is becoming increasingly important. Magnetic resonance imaging (MRI) of the hip does present technical difficulties. The fairly thin cartilage lining necessitates high image resolution and high contrast-to-noise ratio (CNR). With MR arthrography (MRA) using intraarticular injected gadolinium, labral tears and cartilage clefts may be better identified through the contrast medium filling into the clefts. However, the ability of MRA to detect varying grades of cartilage damage is fairly limited and early histological and biochemical changes in the beginning of osteoarthritis (OA) cannot be accurately delineated. Traditional MRI thus lacks the ability to analyze the biological status of cartilage degeneration. The technique of delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is sensitive to the charge density of cartilage contributed by glycosaminoglycans (GAGs), which are lost early in the process of OA. Therefore, the dGEMRIC technique has a potential to detect early cartilage damage that is obviously critical for decision-making regarding time and extent of intervention for joint-preservation. In the last decade, cartilage imaging with dGEMRIC has been established as an accurate and reliable tool for assessment of cartilage status in the knee and hip joint. This review outlines the current status of dGEMRIC for assessment of hip joint cartilage. Practical modifications of the standard technique including three-dimensional (3D) dGEMRIC and dGEMRIC after intra-articular gadolinium instead of iv-dGEMRIC will also be addressed.

scholarly journals Delayed gadolinium-enhanced magnetic resonance imaging (dGEMRIC) of hip joint cartilage in femoroacetabular impingement (FAI): Are pre- and postcontrast imaging both necessary?

2009 ◽  
Vol 62 (6) ◽  
pp. 1362-1367 ◽  
Author(s):  
Bernd Bittersohl ◽  
Harish S. Hosalkar ◽  
Young-Jo Kim ◽  
Stefan Werlen ◽  
Klaus A. Siebenrock ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Femoroacetabular Impingement ◽  
Hip Joint ◽  
Joint Cartilage ◽  
Resonance Imaging
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