Replacing single-view mediolateral oblique (MLO) digital mammography (DM) with synthesized mammography (SM) with digital breast tomosynthesis (DBT) images: Comparison of the diagnostic performance and radiation dose with two-view DM with or without MLO-DBT

2016 ◽  
Vol 85 (11) ◽  
pp. 2042-2048 ◽  
Author(s):  
Hyo-Jin Kang ◽  
Jung Min Chang ◽  
Joongyub Lee ◽  
Sung Eun Song ◽  
Sung Ui Shin ◽  
...  
Keyword(s):  
Radiation Dose ◽  
Digital Mammography ◽  
Diagnostic Performance ◽  
Digital Breast Tomosynthesis ◽  
Breast Tomosynthesis ◽  
Single View

Performance comparison of single-view digital breast tomosynthesis plus single-view digital mammography with two-view digital mammography

2012 ◽  
Vol 23 (3) ◽  
pp. 664-672 ◽  
Author(s):  
Gisella Gennaro ◽  
R. Edward Hendrick ◽  
Patricia Ruppel ◽  
Roberta Chersevani ◽  
Cosimo di Maggio ◽  
...  
Keyword(s):  
Digital Mammography ◽  
Digital Breast Tomosynthesis ◽  
Performance Comparison ◽  
Breast Tomosynthesis ◽  
Single View

scholarly journals One view or two views for wide-angle tomosynthesis with synthetic mammography in the assessment setting?

2021 ◽  
Author(s):  
Paola Clauser ◽  
Pascal A. T. Baltzer ◽  
Panagiotis Kapetas ◽  
Ramona Woitek ◽  
Michael Weber ◽  
...  
Keyword(s):  
Digital Mammography ◽  
Detection Rate ◽  
Diagnostic Performance ◽  
Digital Breast Tomosynthesis ◽  
Rate Sensitivity ◽  
Breast Lesions ◽  
Wide Angle ◽  
Breast Tomosynthesis ◽  
Lesion Type ◽  
Sensitivity Specificity

Abstract Objectives To evaluate the diagnostic performance in the assessment setting of three protocols: one-view wide-angle digital breast tomosynthesis (WA-DBT) with synthetic mammography (SM), two-view WA-DBT/SM, and two-view digital mammography (DM). Methods Included in this retrospective study were patients who underwent bilateral two-view DM and WA-DBT. SM were reconstructed from the WA-DBT data. The standard of reference was histology and/or 2 years follow-up. Included were 205 women with 179 lesions (89 malignant, 90 benign). Four blinded readers randomly evaluated images to assess density, lesion type, and level of suspicion according to BI-RADS. Three protocols were evaluated: two-view DM, one-view (mediolateral oblique) WA-DBT/SM, and two-view WA-DBT/SM. Detection rate, sensitivity, specificity, and accuracy were calculated and compared using multivariate analysis. Reading time was assessed. Results The detection rate was higher with two-view WA-DBT/SM (p = 0.063). Sensitivity was higher for two-view WA-DBT/SM compared to two-view DM (p = 0.001) and one-view WA-DBT/SM (p = 0.058). No significant differences in specificity were found. Accuracy was higher with both one-view WA-DBT/SM and two-view WA-DBT/SM compared to DM (p = 0.003 and > 0.001, respectively). Accuracy did not differ between one- and two-view WA-DBT/SM. Two-view WA-DBT/SM performed better for masses and asymmetries. Reading times were significantly longer when WA-DBT was evaluated. Conclusions One-view and two-view WA-DBT/SM can achieve a higher diagnostic performance compared to two-view DM. The detection rate and sensitivity were highest with two-view WA-DBT/SM. Two-view WA-DBT/SM appears to be the most appropriate tool for the assessment of breast lesions. Key Points • Detection rate with two-view wide-angle digital breast tomosynthesis (WA-DBT) is significantly higher than with two-view digital mammography in the assessment setting. • Diagnostic accuracy of one-view and two-view WA-DBT with synthetic mammography (SM) in the assessment setting is higher than that of two-view digital mammography. • Compared to one-view WA-DBT with SM, two-view WA-DBT with SM seems to be the most appropriate tool for the assessment of breast lesions.

Comparison of Microcalcifications Detection and Characterization in Digital Breast Tomosynthesis (DBT) With Synthesized 2D Mammography (SM) versus DBT with Full-Field Digital Mammography (FFDM)

2021 ◽  
Vol 104 (9) ◽  
pp. 1503-1510
Keyword(s):  
Radiation Dose ◽  
Sensitivity And Specificity ◽  
Digital Mammography ◽  
Digital Breast Tomosynthesis ◽  
Breast Tomosynthesis ◽  
Full Field ◽  
Full Field Digital Mammography

Background: Synthesized 2D mammography (SM) has been invented to help lower the radiation dose by circumventing the need for acquiring full-field digital mammography (FFDM) when digital breast tomosynthesis (DBT) is performed. Prior studies have compared microcalcifications detection and characterization in FFDM with SM or with DBT alone. Only few studies have compared DBT plus SM and DBT plus FFDM. Objective: To determine the performance of DBT with SM versus DBT with FFDM in detection and characterization of microcalcifications. Materials and Methods: Three hundred three paired examinations of 2D plus DBT images in the same session were performed. Fifty-five biopsyproven malignancy, 198 biopsy-proven benign microcalcifications, and 50 randomly selected negative screening studies were retrospectively reviewed by two radiologists. Comparison of sensitivity and specificity between the two modalities were performed. Results: From the 55 malignant microcalcifications, three cases were missed by DBT with FFDM but detected and correctly categorized as malignant by DBT with SM. Only one case of malignant microcalcifications was not detected by DBT with SM, and the present case was also miscategorized as benign by DBT with FFDM. There were no statistically significant differences in both detections (p=0.42), and characterization (p=0.65) of microcalcification between both modalities. In DBT with SM, the sensitivity was higher, and the specificity was lower for both detection and characterization of microcalcification when compared to DBT with FFDM. Conclusion: DBT in combination with SM is comparable to DBT in combination with FFDM for detection and characterization of microcalcifications. Keywords: Synthesized 2D mammography; Full-field digital mammography; Digital breast tomosynthesis; Microcalcifications detection and characterization

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