Predictive Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer: A Monocentric Study of Salah Azaiez Institute

2020 ◽  
Vol 46 (2) ◽  
pp. e37-e38
Author(s):  
Imen Zawati ◽  
Sabrine Boukhris ◽  
Marwa Manai ◽  
Aida Goucha ◽  
Ilhem Bettaieb ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Predictive Markers ◽  
Response To Neoadjuvant Chemotherapy

scholarly journals Assessment of Predictive Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer

2010 ◽  
Vol 33 (4) ◽  
pp. 157-167 ◽  
Author(s):  
Mallika Tewari ◽  
Satyajit Pradhan ◽  
Usha Singh ◽  
Taj Bali Singh ◽  
Hari Shankar Shukla
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Predictive Markers ◽  
Response To Neoadjuvant Chemotherapy

scholarly journals Breast cancer response to neoadjuvant chemotherapy: predictive markers and relation with outcome

2003 ◽  
Vol 88 (3) ◽  
pp. 406-412 ◽  
Author(s):  
I F Faneyte ◽  
J G Schrama ◽  
J L Peterse ◽  
P L Remijnse ◽  
S Rodenhuis ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Predictive Markers ◽  
Response To Neoadjuvant Chemotherapy

Chemotherapy-induced amennorrhea: Predictive markers of response to neoadjuvant chemotherapy in breast cancer.

2011 ◽  
Vol 29 (27_suppl) ◽  
pp. 281-281
Author(s):  
S. K. Ahn ◽  
H. Moon ◽  
E. Ko ◽  
J. s. Kim ◽  
J. M. You ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Cancer Patients ◽  
Tumor Response ◽  
Locally Advanced Breast Cancer ◽  
Univariate Analysis ◽  
Locally Advanced ◽  
Predictive Markers ◽  
Breast Cancer Patients ◽  
Response To Neoadjuvant Chemotherapy

281 Background: There is controversy about the benefit of chemotherapy-induced amenorrhea (CIA) in breast cancer. We investigated significance of CIA after neoadjuvant chemotherapy for predicting response to neoadjuvant chemotherapy in breast cancer patients. Methods: We reviewed the records of 198 premenopausal patients with breast cancer treated with neoadjuvant chemotherapy between January 2005 and December 2010. Chemotherapy-induced amenorrhea (CIA) was defined as serum FSH level ≥40 IU/L after completion of all scheduled neoadjuvant chemotherapy and prior to definitive surgery. Results: Among 198 breast cancer patients, 132 pts (66.7%) developed CIA after neoadjuvant chemotherapy. 156 pts (78%) underwent DA chemotherapy. The age of CIA patients was older than non-CIA patients (41.55±5.55 vs. 38.27± 6.86 years, p=0.001). The incidence of CIA after neoadjuvant chemotherapy was significantly higher in responder group (responder vs. nonresponder: 87 pts (74.4%) vs. 45 pts (55.6%); p=0.006). Additionally, FSH level after all scheduled neoadjuvant chemotherapy was significantly higher in responder group (FSH 56.41±32.41 mIU/ml vs. 45.76±30.31 mIU/ml; p=0.021). In univariate analysis, CIA (p=0.006) and total number of chemotherapy cycle regardless of chemotherapy regimen (p=0.04) were significantly predictive of tumor response. CIA was only significant predictive factor for tumor response after neoadjuvant chemotherapy on multivariate analysis (p=0.012). Conclusions: CIA is independent predictive markers of response to neoadjuvant chemotherapy in locally advanced breast cancer.

Predictive markers of response to neoadjuvant chemotherapy in breast cancer

2008 ◽  
Vol 17 (4) ◽  
pp. 301-311 ◽  
Author(s):  
Mallika Tewari ◽  
Arvind Krishnamurthy ◽  
Hari S. Shukla
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Predictive Markers ◽  
Response To Neoadjuvant Chemotherapy

64P Mammographic density to predict response to neoadjuvant chemotherapy for breast cancer

2021 ◽  
Vol 32 ◽  
pp. S49
Author(s):  
S. Di Cosimo ◽  
C. Depretto ◽  
R. Miceli ◽  
P. Baili ◽  
M. Sant ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Mammographic Density ◽  
Response To Neoadjuvant Chemotherapy
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