Hemodynamic Assessment of Celiaco-mesenteric Anastomosis in Patients with Pancreaticoduodenal Artery Aneurysm Concomitant with Celiac Artery Occlusion using Flow-sensitive Four-dimensional Magnetic Resonance Imaging

A pancreaticoduodenal artery (PDA) aneurysm develops due to increased flow through the pancreaticoduodenal arcade in the setting of celiac or superior mesenteric artery occlusion. Additionally, there is no evidence on the computed tomography scan or angiography images that the dissection process extends to the PDA arcade. Moreover, the optimal treatment protocols for PDA aneurysms with celiac artery obstruction and for celiac artery dissection are controversial. We report 2 cases of ruptured PDA aneurysms caused by celiac artery obstruction due to celiac artery dissection in which the aneurysm was excluded, but celiac artery revascularization was not performed successfully. Our cases indicate that endovascular management for ruptured PDA aneurysms and conservative management for celiac artery obstruction due to celiac artery dissection are feasible as first-line treatment in such cases.

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In vivo tracking of human adipose-derived stem cells labeled with ferumoxytol in rats with middle cerebral artery occlusion by magnetic resonance imaging

Neural Regeneration Research ◽

10.4103/1673-5374.158355 ◽

2015 ◽

Vol 10 (6) ◽

pp. 909 ◽

Cited By ~ 8

Author(s):

Chang-bin Jiang ◽

Jing Liu ◽

Yan Yin ◽

Xiang Zhou ◽

Xin Guan ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Stem Cells ◽

Magnetic Resonance ◽

Middle Cerebral Artery ◽

Middle Cerebral Artery Occlusion ◽

Artery Occlusion ◽

Adipose Derived Stem Cells ◽

Resonance Imaging ◽

Cerebral Artery Occlusion

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Spectacular Shrinking Deficit: Insights from Multimodal Magnetic Resonance Imaging after Embolic Middle Cerebral Artery Occlusion in Sprague—Dawley Rats

Journal of Cerebral Blood Flow & Metabolism ◽

10.1038/sj.jcbfm.9600477 ◽

2007 ◽

Vol 27 (10) ◽

pp. 1756-1763 ◽

Cited By ~ 11

Author(s):

Nils Henninger ◽

Kenneth M Sicard ◽

Marc Fisher

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Functional Magnetic Resonance Imaging ◽

Middle Cerebral Artery ◽

Artery Occlusion ◽

Functional Magnetic Resonance ◽

Resonance Imaging ◽

Sprague Dawley ◽

Sprague Dawley Rats ◽

Cerebral Artery Occlusion

Almost no data is available on the serial changes in the brain after spectacular shrinking deficit (SSD) that may help understand this relatively rare clinical phenomenon. Quantitative diffusion-(DWI), perfusion-(PWI), T1-(T1WI), T2-weighted (T2WI), and functional magnetic resonance imaging (fMRI) were performed before, during, and up to 7 days after embolic middle cerebral artery occlusion (eMCAO) in male Sprague—Dawley rats ( n = 9). Region of interest (ROI) analysis was used to evaluate structural and functional MR signal changes within three ROIs defined by the apparent diffusion coefficient (ADC), cerebral blood flow (CBF) signatures, and final tissue viability. DWI, PWI, and T2WI lesion volumes were calculated using previously established viability thresholds and final infarct volumes ascertained with 2,3,5-triphenyltetrazolium chloride (TTC) staining. Serial MRI demonstrated spontaneous reperfusion of initially hypoperfused MCA regions accompanied by substantial reduction of initial ADC and CBF lesions and gradual recovery of neurological outcome. Recovery rates of CBF/ADC abnormalities differed among ROIs. Functional magnetic resonance imaging showed persistent tissue dysfunction after the recovery of the CBF/ADC lesions. This study may facilitate our understanding of the pathophysiological mechanisms by which early, spontaneous reperfusion affects tissue fate and neurological function.

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Hemodynamic Analysis to Assist Treatment Strategies in Complex Visceral Arterial Pathologies: Case Reports and discussion from Pancreaticoduodenal Artery Aneurysm with Superior Mesenteric Artery Occlusion

Annals of Vascular Surgery ◽

10.1016/j.avsg.2019.02.049 ◽

2019 ◽

Vol 59 ◽

pp. 308.e1-308.e8

Author(s):

Da Li ◽

Jinman Ma ◽

Chijun Wei ◽

Jichun Zhao ◽

Ding Yuan ◽

...

Keyword(s):

Superior Mesenteric Artery ◽

Mesenteric Artery ◽

Case Reports ◽

Treatment Strategies ◽

Artery Aneurysm ◽

Artery Occlusion ◽

Pancreaticoduodenal Artery ◽

Superior Mesenteric Artery Occlusion ◽

Pancreaticoduodenal Artery Aneurysm ◽

Mesenteric Artery Occlusion

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Sodium-23 Magnetic Resonance Imaging Has Potential for Improving Penumbra Detection but Not for Estimating Stroke Onset Time

Journal of Cerebral Blood Flow & Metabolism ◽

10.1038/jcbfm.2014.174 ◽

2014 ◽

Vol 35 (1) ◽

pp. 103-110 ◽

Cited By ~ 9

Author(s):

Friedrich Wetterling ◽

Lindsay Gallagher ◽

Jim Mullin ◽

William M Holmes ◽

Chris McCabe ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Onset Time ◽

Sodium Concentration ◽

Artery Occlusion ◽

Stroke Onset ◽

Resonance Imaging ◽

Sodium Mri ◽

The Core ◽

Tissue Sodium

Tissue sodium concentration increases in irreversibly damaged (core) tissue following ischemic stroke and can potentially help to differentiate the core from the adjacent hypoperfused but viable penumbra. To test this, multinuclear hydrogen-1/sodium-23 magnetic resonance imaging (MRI) was used to measure the changing sodium signal and hydrogen-apparent diffusion coefficient (ADC) in the ischemic core and penumbra after rat middle cerebral artery occlusion (MCAO). Penumbra and core were defined from perfusion imaging and histologically defined irreversibly damaged tissue. The sodium signal in the core increased linearly with time, whereas the ADC rapidly decreased by >30% within 20 minutes of stroke onset, with very little change thereafter (0.5–6 hours after MCAO). Previous reports suggest that the time point at which tissue sodium signal starts to rise above normal (onset of elevated tissue sodium, OETS) represents stroke onset time (SOT). However, extrapolating core data back in time resulted in a delay of 72±24 minutes in OETS compared with actual SOT. At the OETS in the core, penumbra sodium signal was significantly decreased (88±6%, P=0.0008), whereas penumbra ADC was not significantly different (92±18%, P=0.2) from contralateral tissue. In conclusion, reduced sodium-MRI signal may serve as a viability marker for penumbra detection and can complement hydrogen ADC and perfusion MRI in the time-independent assessment of tissue fate in acute stroke patients.

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