scholarly journals Surgical Thrombectomy After Large Vessel Ischaemic Stroke: A Case Report

2021 ◽  
Vol 50 ◽  
pp. 46-47
Author(s):  
João S. Peixoto ◽  
José P. Brandão ◽  
Clara Nogueira ◽  
Andreia Coelho ◽  
Rita Augusto ◽  
...  
BMJ Open ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. e043665
Author(s):  
Srinivasa Rao Kundeti ◽  
Manikanda Krishnan Vaidyanathan ◽  
Bharath Shivashankar ◽  
Sankar Prasad Gorthi

IntroductionThe use of artificial intelligence (AI) to support the diagnosis of acute ischaemic stroke (AIS) could improve patient outcomes and facilitate accurate tissue and vessel assessment. However, the evidence in published AI studies is inadequate and difficult to interpret which reduces the accountability of the diagnostic results in clinical settings. This study protocol describes a rigorous systematic review of the accuracy of AI in the diagnosis of AIS and detection of large-vessel occlusions (LVOs).Methods and analysisWe will perform a systematic review and meta-analysis of the performance of AI models for diagnosing AIS and detecting LVOs. We will adhere to the Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocols guidelines. Literature searches will be conducted in eight databases. For data screening and extraction, two reviewers will use a modified Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies checklist. We will assess the included studies using the Quality Assessment of Diagnostic Accuracy Studies guidelines. We will conduct a meta-analysis if sufficient data are available. We will use hierarchical summary receiver operating characteristic curves to estimate the summary operating points, including the pooled sensitivity and specificity, with 95% CIs, if pooling is appropriate. Furthermore, if sufficient data are available, we will use Grading of Recommendations, Assessment, Development and Evaluations profiler software to summarise the main findings of the systematic review, as a summary of results.Ethics and disseminationThere are no ethical considerations associated with this study protocol, as the systematic review focuses on the examination of secondary data. The systematic review results will be used to report on the accuracy, completeness and standard procedures of the included studies. We will disseminate our findings by publishing our analysis in a peer-reviewed journal and, if required, we will communicate with the stakeholders of the studies and bibliographic databases.PROSPERO registration numberCRD42020179652.


2017 ◽  
Vol 282 (6) ◽  
pp. 537-545 ◽  
Author(s):  
R. Motyer ◽  
H. K. Kok ◽  
H. Asadi ◽  
A. O'Hare ◽  
P. Brennan ◽  
...  

2007 ◽  
Vol 11 ◽  
pp. 66
Author(s):  
S. Lekka ◽  
A. Xaidara ◽  
H. Platokouki ◽  
S. Youroukos

2019 ◽  
Vol 49 (3) ◽  
pp. 345-351 ◽  
Author(s):  
Julian Maingard ◽  
Yasmin Shvarts ◽  
Ronan Motyer ◽  
Vincent Thijs ◽  
Paul Brennan ◽  
...  

Author(s):  
Tarali Devi ◽  
Subhash Sarma ◽  
Urmi Choudhury

<p>Cerebroprotein hydrolysate is a newer pharmacological neurotropic agent and considered as a promising therapeutic agent for dementia, Alzheimer’s disease, traumatic brain injury and acute ischaemic stroke. Studies revealed that most of the side effects are minor. Here, we reported a case of Systemic inflammatory response syndrome (SIRS) probably due to use of Cerebroprotein hydrolysate in a patient with acute ischaemic stroke.</p>


2006 ◽  
Vol 38 (9) ◽  
pp. 3135-3137 ◽  
Author(s):  
A. Gladysz-Polak ◽  
W.G. Polak ◽  
P. Jazwiec ◽  
P.J. Chudoba ◽  
A. Halon ◽  
...  

2018 ◽  
Vol 24 (5) ◽  
pp. 529-532 ◽  
Author(s):  
Manuel Bolognese ◽  
Alexander von Hessling ◽  
Martin Müller

Neurological complications of infective endocarditis are frequent, especially ischaemic strokes. As intravenous thrombolysis in infective endocarditis-related ischaemic stroke has a controversial benefit/risk ratio, alternative treatment regimens have to be considered. We present the case of a young patient with septic embolism of the middle cerebral artery who was successfully treated with mechanical thrombectomy, and give a short review of the existing literature.


2018 ◽  
Vol 46 (1-2) ◽  
pp. 24-32 ◽  
Author(s):  
Alexandre Gauthier ◽  
Patrick Gérardin ◽  
Pauline Renou ◽  
Sharmila Sagnier ◽  
Sabrina Debruxelles ◽  
...  

Background: Along with pharmacological and mechanical recanalization, improving cerebral perfusion through the recruitment of collateral vessels during the acute phase of ischaemic stroke (IS) is a clinical challenge. Our objective was to assess the effectiveness and safety of Trendelenburg positioning (TP), a procedure intended to increase cerebral blood flow, on the outcome of IS. Methods: Two cohorts of patients with an acute supratentorial IS related to a large artery occlusion were compared. In the first cohort (n = 119), we used standard positioning (0 to +30°); in the second cohort (n = 90), we used TP (0 to –15°). The primary outcome measure was the improvement of National Institutes of Health Stroke Scale (NIHSS) score between admission and day 2. Factors associated with an improvement ≥4 points of NIHSS score were assessed using multiple logistic regression and propensity score (PS) matching analyses. Results: TP was significantly associated with a greater improvement of NIHSS score within 48 h following stroke onset (4.0 ± 5.7 vs. 1.8 ± 5.9, p = 0.011) but also at discharge (p = 0.005). Multiple logistic regression analysis suggested that TP was an independent predictor of early neurological improvement (adjusted OR 1.81, 95% CI 1.00–3.27) in a model controlling recanalization and haemoglobin level. In addition, PS matching analysis confirmed the possible effectiveness of TP (unadjusted OR 1.99, 95% CI 1.04–3.82), especially in male subjects. The effect of TP was more pronounced in patients with admission mean arterial blood pressure ≥100 mm Hg, those exhibiting a good collateral vessel network on admission CT-angiography or experiencing an effective recanalization. Furthermore, TP was not associated with life-threatening complications. Conclusion: TP could be an effective and safe strategy in patients with large IS resulting from the proximal occlusion of a large vessel.


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