Selective determination of L-dopa in the presence of uric acid and ascorbic acid at a gold nanoparticle self-assembled carbon nanotube-modified pyrolytic graphite electrode

2010 ◽  
Vol 55 (16) ◽  
pp. 4711-4716 ◽  
Author(s):  
Guangzhi Hu ◽  
Long Chen ◽  
Yong Guo ◽  
Xiaolai Wang ◽  
Shijun Shao
2011 ◽  
Vol 81 (2) ◽  
pp. 104-108 ◽  
Author(s):  
Malledevaru Mallesha ◽  
Revanasiddappa Manjunatha ◽  
C. Nethravathi ◽  
Gurukar Shivappa Suresh ◽  
Michael Rajamathi ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Rajendra N. Goyal ◽  
Sunita Bishnoi ◽  
Bharati Agrawal

A fast and sensitive voltammetric method has been proposed for the determination of salbutamol at single-walled-carbon-nanotube-modified edge-plane pyrolytic graphite electrode (SWNT/EPPGE) in human urine. The electrochemical response of salbutamol was determined by square wave voltammetry (SWV) in phosphate buffer solution (PBS) at physiological pH 7.2. The modified electrode showed improved voltammetric response towards the oxidation of salbutamol, and a well-defined anodic peak was observed at~600 mV with enhanced peak current in comparison to the bare electrode. Linear calibration plot using SWNT/EPPGE was obtained in the concentration range of 50 to 2500 ngml-1with sensitivity and detection limit of 2.15 nA/ngml-1and 4.31 ngml-1, respectively. The developed method has been successfully applied for the determination of salbutamol in commercial preparations and human body fluids. Fast analysis of salbutamol in human urine makes the proposed method of great interest for doping control purposes at the site of competitive games.


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