Single-Walled-Carbon-Nanotube-Modified Pyrolytic Graphite Electrode Used as a Simple Sensor for the Determination of Salbutamol in Urine

A fast and sensitive voltammetric method has been proposed for the determination of salbutamol at single-walled-carbon-nanotube-modified edge-plane pyrolytic graphite electrode (SWNT/EPPGE) in human urine. The electrochemical response of salbutamol was determined by square wave voltammetry (SWV) in phosphate buffer solution (PBS) at physiological pH 7.2. The modified electrode showed improved voltammetric response towards the oxidation of salbutamol, and a well-defined anodic peak was observed at~600 mV with enhanced peak current in comparison to the bare electrode. Linear calibration plot using SWNT/EPPGE was obtained in the concentration range of 50 to 2500 ngml-1with sensitivity and detection limit of 2.15 nA/ngml-1and 4.31 ngml-1, respectively. The developed method has been successfully applied for the determination of salbutamol in commercial preparations and human body fluids. Fast analysis of salbutamol in human urine makes the proposed method of great interest for doping control purposes at the site of competitive games.

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Effect of single walled carbon nanotube–cetyltrimethyl ammonium bromide nanocomposite film modified pyrolytic graphite on the determination of betamethasone in human urine

Colloids and Surfaces B Biointerfaces ◽

10.1016/j.colsurfb.2010.01.024 ◽

2010 ◽

Vol 77 (2) ◽

pp. 200-205 ◽

Cited By ~ 11

Author(s):

Rajendra N. Goyal ◽

Sunita Bishnoi

Keyword(s):

Carbon Nanotube ◽

Human Urine ◽

Nanocomposite Film ◽

Pyrolytic Graphite ◽

Ammonium Bromide ◽

Cetyltrimethyl Ammonium Bromide ◽

Single Walled Carbon Nanotube ◽

Single Walled Carbon ◽

Cetyltrimethyl Ammonium

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Achievements of Mesoporous Carbon Solution and Single-Walled Carbon Nanotube Composite on the Sensitive Electrochemical Assay of Ivabradine

Analytica ◽

10.3390/analytica2040017 ◽

2021 ◽

Vol 2 (4) ◽

pp. 195-205

Author(s):

Merve Yence ◽

Leyla Karadurmus ◽

Goksu Ozcelikay ◽

Nurgul K. Bakirhan ◽

Sibel A. Ozkan

Keyword(s):

Carbon Nanotube ◽

Mesoporous Carbon ◽

Urine Analysis ◽

Calibration Plot ◽

Electrochemical Assay ◽

Experimental Conditions ◽

Single Walled Carbon Nanotube ◽

Single Walled Carbon ◽

Serum And Urine

In this study, the electrochemical determination of Ivabradine hydrochloride (IH) was studied in detail using a glassy carbon electrode (GCE) modified with mesoporous carbon solution (MCS) and carboxylated group linked single-walled carbon nanotube (SWCNT-COOH). The developed nanosensor showed a significant effect by remarkably increasing the IH signal compared with the bare GCE. Cyclic (CV) and differential pulse voltammetric (DPV) methods were applied to perform electrochemical analysis of IH in pH 3.0 BRB solutions. The calibration plot for IH with a detection limit of 1.47 × 10−7 M was obtained using the DPV technique in the range of 1–10 µM under optimum experimental conditions. The proposed method has been validated and applied for the detection of the IH tablet. The produced nanosensor was also performed for the determination of IH in serum and urine. Excellent recoveries of 98.4%, 98.0%, and 100.2% were achieved for tablet, serum, and urine analysis, respectively.

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