Fabrication of DNA electrochemical biosensor based on gold nanoparticles, locked nucleic acid modified hairpin DNA and enzymatic signal amplification

2012 ◽  
Vol 71 ◽  
pp. 233-238 ◽  
Author(s):  
Xiaomeng Meng ◽  
Minrong Xu ◽  
Jianying Zhu ◽  
Huanshun Yin ◽  
Shiyun Ai
Keyword(s):  
Gold Nanoparticles ◽  
Nucleic Acid ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Locked Nucleic Acid ◽  
Hairpin Dna ◽  
Dna Electrochemical Biosensor ◽  
Enzymatic Signal Amplification

Sensitive electrochemical biosensor for MicroRNAs based on duplex-specific nuclease-assisted target recycling followed with gold nanoparticles and enzymatic signal amplification

2019 ◽  
Vol 1064 ◽  
pp. 33-39 ◽  
Author(s):  
Hui Zhang ◽  
Mengxing Fan ◽  
Juqian Jiang ◽  
Qingming Shen ◽  
Chenxin Cai ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Target Recycling ◽  
Enzymatic Signal Amplification

A highly sensitive electrochemical microRNA-21 biosensor based on intercalating methylene blue signal amplification and a highly dispersed gold nanoparticles/graphene/polypyrrole composite

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Highly Sensitive ◽  
Highly Dispersed ◽  
Polypyrrole Composite ◽  
Amplification Strategy ◽  
Dispersed Gold ◽  
Potential Tool

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.

Ultrasensitive DNA electrochemical biosensor based on MnTBAP biomimetic catalyzed AGET ATRP signal amplification reaction

2020 ◽  
Vol 56 (49) ◽  
pp. 6636-6639
Author(s):  
Haobo Sun ◽  
Yunliang Qiu ◽  
Yajie Lu ◽  
Jinming Kong ◽  
Xueji Zhang
Keyword(s):  
Dna Sequences ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Aget Atrp ◽  
Dna Electrochemical Biosensor ◽  
Amplification Reaction

In this paper, an ultrasensitive, highly selective and green electrochemical biosensor for quantifying DNA sequences (aM DNA) based on a MnTBAP catalyst for AGET ATRP reaction is proposed.

A novel electrochemical biosensor for ultrasensitive Hg2+ detection via a triple signal amplification strategy

2021 ◽  
Author(s):  
Wang He ◽  
Bin Qiao ◽  
Fengzhen Li ◽  
Lisha Pan ◽  
Delun Chen ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Nucleic Acid ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Amplification Strategy

We report a novel electrochemical biosensor for the ultrasensitive Hg2+ detection via a signal amplification strategy. This strategy could be easily modified and extended to detect other hazardous heavy metals and nucleic acid.

scholarly journals Optimization of the Electrodeposition of Gold Nanoparticles for the Application of Highly Sensitive, Label-Free Biosensor

Biosensors ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 50 ◽  
Author(s):  
Hao-Chun Chiang ◽  
Yanyan Wang ◽  
Qi Zhang ◽  
Kalle Levon
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Aqueous Electrolyte ◽  
Label Free ◽  
Reduction Step ◽  
Glucose Biosensors ◽  
Highly Sensitive ◽  
Amperometric Glucose Biosensors ◽  
Aunp Surface

A highly sensitive electrochemical biosensor with a signal amplification platform of electrodeposited gold nanoparticle (AuNP) has been developed and characterized. The sizes of the synthesized AuNP were found to be critical for the performance of biosensor in which the sizes were dependent on HAuCl4 and acid concentrations; as well as on scan cycles and scan rates in the gold electro-reduction step. Systematic investigations of the adsorption of proteins with different sizes from aqueous electrolyte solution onto the electrodeposited AuNP surface were performed with a potentiometric method and calibrated by design of experiment (DOE). The resulting amperometric glucose biosensors was demonstrated to have a low detection limit (> 50 μM) and a wide linear range after optimization with AuNP electrodeposition.

A sensitive electrochemical biosensor for detection of protein kinase A activity and inhibitors based on Phos-tag and enzymatic signal amplification

2015 ◽  
Vol 63 ◽  
pp. 26-32 ◽  
Author(s):  
Huanshun Yin ◽  
Mo Wang ◽  
Bingchen Li ◽  
Zhiqing Yang ◽  
Yunlei Zhou ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Protein Kinase A ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Enzymatic Signal Amplification ◽  
Kinase A
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