A novel electrochemical biosensor for ultrasensitive Hg2+ detection via a triple signal amplification strategy

2021 ◽  
Author(s):  
Wang He ◽  
Bin Qiao ◽  
Fengzhen Li ◽  
Lisha Pan ◽  
Delun Chen ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Nucleic Acid ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Amplification Strategy

We report a novel electrochemical biosensor for the ultrasensitive Hg2+ detection via a signal amplification strategy. This strategy could be easily modified and extended to detect other hazardous heavy metals and nucleic acid.

A highly sensitive electrochemical microRNA-21 biosensor based on intercalating methylene blue signal amplification and a highly dispersed gold nanoparticles/graphene/polypyrrole composite

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Highly Sensitive ◽  
Highly Dispersed ◽  
Polypyrrole Composite ◽  
Amplification Strategy ◽  
Dispersed Gold ◽  
Potential Tool

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.

scholarly journals Target-activated transcription for the amplified sensing of protease biomarkers

2020 ◽  
Vol 11 (11) ◽  
pp. 2993-2998 ◽  
Author(s):  
Fang Liu ◽  
Min Yang ◽  
Wenlu Song ◽  
Xingyu Luo ◽  
Rui Tang ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Signal Amplification ◽  
Amplification Strategy

A transcription-inspired signal amplification strategy that amplifies proteolysis into nucleic acid outputs is presented for the ultrasensitive sensing of protease biomarkers.

A “signal-on” electrochemical biosensor based on DNAzyme-driven bipedal DNA walkers and TdT-mediated cascade signal amplification strategy

2020 ◽  
Vol 1100 ◽  
pp. 40-46 ◽  
Author(s):  
Sheng Lei ◽  
Zi Liu ◽  
Lingling Xu ◽  
Lina Zou ◽  
Gaiping Li ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Dna Walkers ◽  
Amplification Strategy

Recent advance in exonuclease Ⅲ-assisted target signal amplification strategy for nucleic acid detection

2021 ◽  
Author(s):  
hongyu liu ◽  
Yuhao You ◽  
Youzhuo Zhu ◽  
Heng Zheng
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Molecular Diagnostics ◽  
Mutation Analysis ◽  
Signal Amplification ◽  
Nucleic Acid Detection ◽  
Target Signal ◽  
Forensic Investigations ◽  
Exo Iii ◽  
Amplification Strategy

Detection of nucleic acids have become significantly important in molecular diagnostics, genetics therapy, mutation analysis, forensic investigations and biomedical development, and so on. In recent years, exonuclease Ⅲ (Exo III)...

Ligase chain reaction-based electrochemical biosensor for the ultrasensitive and specific detection of single nucleotide polymorphisms

2019 ◽  
Vol 43 (36) ◽  
pp. 14327-14335 ◽  
Author(s):  
Wancun Zhang ◽  
Fang Hu ◽  
Xianwei Zhang ◽  
Wei Meng ◽  
Yaodong Zhang ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Nucleotide Polymorphisms ◽  
Specific Detection ◽  
Chain Reaction ◽  
Single Nucleotide ◽  
Ligase Chain Reaction ◽  
Amplification Strategy

In this study, a sensitive electrochemical biosensor for universally, robustly, specifically, and sensitively detecting SNPs was developed by using LCR as a signal amplification strategy.

An ATP-fueled nucleic acid signal amplification strategy for highly sensitive microRNA detection

2018 ◽  
Vol 54 (77) ◽  
pp. 10897-10900 ◽  
Author(s):  
Zhi-Bin Wen ◽  
Wen-Bin Liang ◽  
Ying Zhuo ◽  
Cheng-Yi Xiong ◽  
Ying-Ning Zheng ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Nucleic Acid ◽  
Signal Amplification ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Strand Displacement ◽  
Microrna Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Amplification Strategy

Herein, an adenosine triphosphate (ATP)-fueled nucleic acid signal amplification strategy based on toehold-mediated strand displacement (TMSD) and fluorescence resonance energy transfer (FRET) was proposed for highly sensitive detection of microRNA-21.

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