scholarly journals Functional diagnosis of coronary stenosis using tissue tracking provides best sensitivity and specificity for left circumflex disease: experience from the MYDISE (myocardial Doppler in stress echocardiography) study

2005 ◽  
Vol 6 (1) ◽  
pp. 54-63 ◽  
Author(s):  
S SAHA ◽  
J NOWAK ◽  
C STORAA ◽  
C MADLER ◽  
A FRASER ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Coronary Stenosis ◽  
Stress Echocardiography ◽  
Functional Diagnosis ◽  
Tissue Tracking ◽  
Disease Experience

scholarly journals Stress Echocardiography with Adenosinethreephosphate and Atrial Pacing in Diagnosis of Late Coronary Shunts Stenosis

2021 ◽  
pp. 57-66
Author(s):  
A. V. Talanova ◽  
D. A. Lezhnev ◽  
N. N. Mikheev
Keyword(s):  
Coronary Angiography ◽  
Diagnostic Accuracy ◽  
Sensitivity And Specificity ◽  
Coronary Arteries ◽  
Coronary Stenosis ◽  
Stress Echocardiography ◽  
Atrial Pacing ◽  
Coronary Lesions

The aim of the study was to evaluate diagnostic accuracy of stress echocardiography (stress echoCG) with combination of high doze АТР and atrial pacing in diagnosis of late coronary shunts stenosis.48 men aged from 45 to 64 (48,4 ± 1,6 years), 36 patients undergone mammarocoronary shunting, 12 patients undergone auto venous shunting. Stress echoCG with combination of high doze ATP and atrial pacing suggested shunts lesions in 44 patients, in 8 cases previously intact coronary arteries, approved with coronary angiography. Coronary angiographies reviled no coronary lesions in 24 patients > 70 % shunts restenosis, in 22 coronary stenosis from 50 up to 70 %. Accuracy, sensitivity and specificity of stress- EchoCG with combination of stress-agents in coronary shunts restenosis, as well as stenosis of previously intact coronary arteries were 100 %.

DIAGNOSTICS OF THE ISCHEMIC HEART DISEASE WITH THE USE OF HEART RATE VARIABILITY AND DISPERSION MAPPING OF THE MYOCARDIUM DURING STRESS-ECHOCARDIOGRAPHY

2021 ◽  
Vol 55 (5) ◽  
pp. 53-58
Author(s):  
S.V. Zhuravlev ◽  
◽  
V.N. Ardashev ◽  
E.M. Novikov ◽  
O.M. Maslennikova ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Sensitivity And Specificity ◽  
Stress Echocardiography ◽  
Ischemic Heart ◽  
Diagnostic Tools ◽  
Heart Rate Variability Analysis ◽  
Variability Analysis

The authors present a stress-echocardiography (stress-echoECG) technique enhanced with dispersion mapping and heart rate variability analysis. This combination of diagnostic tools increases IHD diagnostics sensitivity and specificity to 96 and 89 % respectively.

scholarly journals Comparative efficiency of bicycle stresses-echocardiography and dopplerography of coronary arteries in diagnosis of the latent coronary insufficiency

2015 ◽  
Vol 14 (1) ◽  
pp. 32-40
Author(s):  
A. B. Trivozhenko ◽  
S. A. Iaroshuk ◽  
P. V. Struchkov
Keyword(s):  
Sensitivity And Specificity ◽  
Coronary Arteries ◽  
Stress Echocardiography ◽  
Roc Analysis ◽  
Combined Method ◽  
Coronary Insufficiency ◽  
Significant Stenosis ◽  
Comparative Efficiency ◽  
The Right ◽  
Combined Technique

Modern angiographic and stressful ultrasonic technologies possess the big possibilities in diagnostics of the latent coronary insufficiency. Purpose. To compare sensitivity and specificity of bicycle stress-echocardiography, dopplerography of coronary arteries and combined method in diagnostics of significant stenosis of coronary arteries were used. Design/methodology/approach. Two groups of patients were analyzed: 35 persons from more than 50 % stenosis of coronary arteries and 39 persons without significant stenosis. Dopplerography of coronary arteries and stress-echocardiography were performed in all patients. The ROC-analysis of sensitivity and specificity of each method and the combined technology in diagnostics of the general CAD, left anterior-descending CAD, and the right coronary CAD was spent. Findings. The dopplerography of coronary arteries has shown sensitivity of 77 %, specificity of 97 %, for LAD - 81 and 97 %, for RA - 50 and 98 %. The stress-echocardiography has shown sensitivity of 83 %, specificity of 95 %, for LAD - 89 and 95 %, for RA - 63 and 98 % The combined technique has shown sensitivity of 93 %, specificity - 95 %, for LAD - 96 and 94 %, for RA - 75 and 98 %. Conclusion. The combined technique is characterized by the robust reproducibility at the expense of revealing of loading infringements local contractility of myocardium in patients with not detected stenosis, and also at the expense of revealing of vascular narrowing in persons with well developed indemnification of deficiency of a blood-groove on the changed vessel.

scholarly journals Meta-Analysis of Diagnostic Performance of Contrast-Fractional Flow Reserve versus Quantitative Flow Ratio for Functional Assessment of Coronary Stenoses

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Ruitao Zhang ◽  
Jianwei Zhang ◽  
Lijun Guo
Keyword(s):  
Sensitivity And Specificity ◽  
Fractional Flow Reserve ◽  
Coronary Stenosis ◽  
Diagnostic Performance ◽  
Meta Analysis ◽  
Flow Ratio ◽  
Fractional Flow ◽  
Flow Reserve ◽  
Quantitative Flow Ratio ◽  
Quantitative Flow

Background. Use of the fractional flow reserve (FFR) technique is recommended to evaluate coronary stenosis severity and guide revascularization. However, its high cost, time to administer, and the side effects of adenosine reduce its clinical utility. Two novel adenosine-free indices, contrast-FFR (cFFR) and quantitative flow ratio (QFR), can simplify the functional evaluation of coronary stenosis. This study aimed to analyze the diagnostic performance of cFFR and QFR using FFR as a reference index. Methods. We conducted a systematic review and meta-analysis of observational studies in which cFFR or QFR was compared to FFR. A bivariate model was applied to pool diagnostic parameters. Cochran’s Q test and the I2 index were used to assess heterogeneity and identify the potential source of heterogeneity by metaregression and sensitivity analysis. Results. Overall, 2220 and 3000 coronary lesions from 20 studies were evaluated by cFFR and QFR, respectively. The pooled sensitivity and specificity were 0.87 (95% CI: 0.81, 0.91) and 0.92 (95% CI: 0.88, 0.94) for cFFR and 0.87 (95% CI: 0.82, 0.91) and 0.91 (95% CI: 0.87, 0.93) for QFR, respectively. No statistical significance of sensitivity and specificity for cFFR and QFR were observed in the bivariate analysis (P=0.8406 and 0.4397, resp.). The area under summary receiver-operating curve of cFFR and QFR was 0.95 (95% CI: 0.93, 0.97) for cFFR and 0.95 (95% CI: 0.93, 0.97). Conclusion. Both cFFR and QFR have good diagnostic performance in detecting functional severity of coronary arteries and showed similar diagnostic parameters.

scholarly journals A new CFD based non-invasive method for functional diagnosis of coronary stenosis

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Xinzhou Xie ◽  
Minwen Zheng ◽  
Didi Wen ◽  
Yabing Li ◽  
Songyun Xie
Keyword(s):  
Coronary Stenosis ◽  
Functional Diagnosis ◽  
Non Invasive ◽  
Invasive Method

Abstract 2688: Can Stress Echocardiography With Tissue Characterization Evaluate Noncritical Coronary Stenosis? A Validation Study Against Simultaneous Measurement of Fractional Flow Reserve

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Tudor Poerner ◽  
Sisi Vilardi ◽  
Björn Goebel ◽  
Hans R Figulla ◽  
Tim Süselbeck
Keyword(s):  
Myocardial Ischemia ◽  
Strain Rate ◽  
Fractional Flow Reserve ◽  
Coronary Stenosis ◽  
Stress Echocardiography ◽  
Tissue Characterization ◽  
Fractional Flow ◽  
Balloon Inflation ◽  
Exercise Tests ◽  
Flow Reserve

Aim of this study was to evaluate the ability of different echocardiographic modalities to detect myocardial ischemia due to non-critical coronary stenosis, compared to the fractional flow reserve (FFR) as gold standard. Material and Methods: We investigated 22 consecutive patients presenting with stable angina, negative exercise tests and coronary 1-vessel disease with 50–75% diameter stenosis. TDE/SRI was performed at baseline and at peak hyperemia during 0.14 mg/kg/min adenosine infusion simultaneously with intracoronary FFR measurements. Angioplasty was carried out if FFR < 0.75, repeating TDE/SRI during first balloon inflation. Visual wall motion score, peak systolic values for myocardial velocity (Vs), strain rate (SRs), strain (Ss) and peak overall strain (Smax) were determined in the region of interest. Postsystolic shortening (PSS), accepted as typical marker of acute myocardial ischemia, was defined as (Smax-Ss)/Smax > 0.3, with reduced Ss < 15%. Results: Pathologic FFR < 0.75 was found in 11 patients (Table 1 ), who underwent angioplasty. Myocardial contractility reflected by SRs increased during hyperemia only in the patient group with FFR > 0.75 and decreased markedly during balloon inflation. Hyperemic SRs variation correlated with FFR (r = 0.5, p = 0.018) and predicted significantly pathologic FFR with an area under ROC curve of 0.86 (p <0.01). PSS was identified in 10 of 11 patients during vessel occlusion, but had a low sensitivity (2 of 11 patients with FFR < 0.75) for the more subtle changes during hyperemia. Conclusion: Functional assessment of moderate-to-severe coronary stenosis remains a diagnostic challenge. PSS occurrence cannot serve as a reliable noninvasive alternative to FFR. However, the blunted hyperemic variation of systolic strain rate was able to predict a pathologic FFR, even in this small group of patients. Therefore, TDE/SRI emerges as a promising tool to enhance the diagnostic accuracy of adenosine stress echocardiography. Table 1

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