Vietnamese herbal medicine (TD0019) in the treatment of cervical radiculopathy: A double-blind phase-2 randomized controlled trial

2020 ◽  
Vol 36 ◽  
pp. 101060
Author(s):  
Nguyen Thi Thu Ha ◽  
Nguyen Lam Vuong ◽  
Trinh Thi Lua ◽  
Trang Thi Minh Nguyen ◽  
Duong Trong Nghia ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Herbal Medicine ◽  
Controlled Trial ◽  
Cervical Radiculopathy ◽  
Phase 2 ◽  
Double Blind ◽  
Randomized Controlled

scholarly journals Double-blinding of an acupuncture randomized controlled trial optimized with clinical translational science award resources

2020 ◽  
Vol 17 (5) ◽  
pp. 545-551
Author(s):  
Alana D Steffen ◽  
Larisa A Burke ◽  
Heather A Pauls ◽  
Marie L Suarez ◽  
Yingwei Yao ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Systematic Approach ◽  
Controlled Trial ◽  
Phase 2 ◽  
Double Blind ◽  
Randomized Controlled ◽  
Group Assignment ◽  
Trial Testing ◽  
Group Allocation ◽  
Over Time

Background Clinical trial articles often lack detailed descriptions of the methods used to randomize participants, conceal allocation, and blind subjects and investigators to group assignment. We describe our systematic approach to implement and measure blinding success in a double-blind phase 2 randomized controlled trial testing the efficacy of acupuncture for the treatment of vulvodynia. Methods Randomization stratified by vulvodynia subtype is managed by Research Electronic Data Capture software’s randomization module adapted to achieve complete masking of group allocation. Subject and acupuncturist blinding assessments are conducted multiple times to identify possible correlates of unblinding. Results At present, 48 subjects have been randomized and completed the protocol resulting in 87 subject and 206 acupuncturist blinding assessments. Discussion Our approach to blinding and blinding assessment has the potential to improve our understanding of unblinding over time in the presence of possible clinical improvement.

scholarly journals Postprandial effects of dark chocolate on portal hypertension in patients with cirrhosis: results of a phase 2, double-blind, randomized controlled trial

2012 ◽  
Vol 96 (3) ◽  
pp. 584-590 ◽  
Author(s):  
Andrea De Gottardi ◽  
Annalisa Berzigotti ◽  
Susana Seijo ◽  
Mario D'Amico ◽  
Wolfgang Thormann ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Portal Hypertension ◽  
Controlled Trial ◽  
Dark Chocolate ◽  
Phase 2 ◽  
Double Blind ◽  
Randomized Controlled
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