Polyprodrug with ultra-high drug content for tumor intracellular acid-triggered degradation and drug delivery

2021 ◽  
pp. 110820
Author(s):  
Xinming Li ◽  
Xiaomei Zhao ◽  
Peng Liu
Keyword(s):  
Drug Delivery ◽  
High Drug ◽  
Drug Content ◽  
Intracellular Acid

Fully synthetic injectable depots with high drug content and tunable pharmacokinetics for long-acting drug delivery

2021 ◽  
Vol 329 ◽  
pp. 257-269
Author(s):  
Duy-Khiet Ho ◽  
Clare LeGuyader ◽  
Selvi Srinivasan ◽  
Debashish Roy ◽  
Vladimir Vlaskin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
High Drug ◽  
Drug Content ◽  
Long Acting

Biomimetic pseudopolyrotaxane prodrug micelles with high drug content for intracellular drug delivery

2013 ◽  
Vol 49 (64) ◽  
pp. 7123 ◽  
Author(s):  
Yin Wang ◽  
Haibo Wang ◽  
Yangjun Chen ◽  
Xiangsheng Liu ◽  
Qiao Jin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
High Drug ◽  
Drug Content ◽  
Intracellular Drug Delivery

Prodrugs Forming High Drug Loading Multifunctional Nanocapsules for Intracellular Cancer Drug Delivery

2010 ◽  
Vol 132 (12) ◽  
pp. 4259-4265 ◽  
Author(s):  
Youqing Shen ◽  
Erlei Jin ◽  
Bo Zhang ◽  
Caitlin J. Murphy ◽  
Meihua Sui ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Loading ◽  
Cancer Drug ◽  
High Drug ◽  
Cancer Drug Delivery ◽  
High Drug Loading

A novel high drug loading mussel-inspired polydopamine hybrid nanoparticle as a pH-sensitive vehicle for drug delivery

2017 ◽  
Vol 533 (1) ◽  
pp. 73-83 ◽  
Author(s):  
Jie Hou ◽  
Chunlei Guo ◽  
Yuzhi Shi ◽  
Ergang Liu ◽  
Weibing Dong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Loading ◽  
Ph Sensitive ◽  
High Drug ◽  
Hybrid Nanoparticle ◽  
High Drug Loading

Peptide-functionalized and high drug loaded novel nanoparticles as dual-targeting drug delivery system for modulated and controlled release of paclitaxel to brain glioma

2018 ◽  
Vol 553 (1-2) ◽  
pp. 169-185 ◽  
Author(s):  
Primiano Pio Di Mauro ◽  
Anna Cascante ◽  
Pau Brugada Vilà ◽  
Vanessa Gómez-Vallejo ◽  
Jordi Llop ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Brain Glioma ◽  
High Drug ◽  
Dual Targeting

scholarly journals A facile doxorubicin-dichloroacetate conjugate nanomedicine with high drug loading for safe drug delivery

2018 ◽  
Vol Volume 13 ◽  
pp. 1281-1293 ◽  
Author(s):  
Conglian Yang ◽  
Tingting Wu ◽  
Yuting Qin ◽  
Yan Qi ◽  
Yu Sun ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Loading ◽  
High Drug ◽  
High Drug Loading

A γ-cyclodextrin-based metal–organic framework embedded with graphene quantum dots and modified with PEGMA via SI-ATRP for anticancer drug delivery and therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (43) ◽  
pp. 20956-20967 ◽  
Author(s):  
Qiaojuan Jia ◽  
Zhenzhen Li ◽  
Chuanpan Guo ◽  
Xiaoyu Huang ◽  
Yingpan Song ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Drug Loading ◽  
Graphene Quantum Dots ◽  
Tumor Growth Inhibition ◽  
High Drug ◽  
Anticancer Drug Delivery ◽  
Metal Organic ◽  
High Drug Loading

A biocompatible γ-CD-MOF based DDS with high drug loading and full drug release was prepared and effective tumor growth inhibition was achieved in vivo.

Glutathione-Sensitive Hyaluronic Acid-SS-Mertansine Prodrug with a High Drug Content: Facile Synthesis and Targeted Breast Tumor Therapy

2016 ◽  
Vol 17 (11) ◽  
pp. 3602-3608 ◽  
Author(s):  
Ping Zhong ◽  
Jian Zhang ◽  
Chao Deng ◽  
Ru Cheng ◽  
Fenghua Meng ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Breast Tumor ◽  
Tumor Therapy ◽  
Facile Synthesis ◽  
High Drug ◽  
Drug Content

Supramolecular micellar drug delivery system based on multi-arm block copolymer for highly effective encapsulation and sustained-release chemotherapy

2019 ◽  
Vol 7 (37) ◽  
pp. 5677-5687 ◽  
Author(s):  
Li Zhang ◽  
Dongjian Shi ◽  
Chunling Shi ◽  
Tatsuo Kaneko ◽  
Mingqing Chen
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Sustained Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Loading ◽  
High Drug ◽  
Release Drug ◽  
Drug Loading Efficiency ◽  
High Drug Loading

A novel multi-arm polyphosphoester-based nanomaterial provides high drug loading efficiency and sustained-release drug delivery for effective chemotherapy.

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